The Chicago Bulls have the highest point differential by a team in a game 6, with a 54 point differential in Game 6 of the 2015 First Round against the Bucks.

	TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Bulls	54	4/30/2015	CHI	@	MIL	W 120-66	240	120	50	31	7	2	46	90	51.1	15	30	50.0	13	16	81.3	61.8	10	40	12	14
2	Timberwolves	45	5/16/2024	MIN	vs	DEN	W 115-70	240	115	62	26	9	4	40	86	46.5	15	40	37.5	20	24	83.3	59.5	11	51	6	14
3	Lakers	40	4/28/2023	LAL	vs	MEM	W 125-85	240	125	52	33	6	15	49	91	53.8	15	44	34.1	12	15	80.0	64.0	9	43	13	16
4	Lakers	40	4/5/1969	LAL	@	SFW	W 118-78	240	118	69	28			48	98	49.0				22	30	73.3	53.1				18
5	Spurs	39	5/11/2017	SAS	@	HOU	W 114-75	240	114	60	32	8	9	51	96	53.1	5	22	22.7	7	13	53.8	56.0	14	46	7	21
6	Celtics	39	6/17/2008	BOS	vs	LAL	W 131-92	240	131	48	33	18	4	43	87	49.4	13	26	50.0	32	37	86.5	63.4	14	34	7	25
7	Knicks	38	5/16/2025	NYK	vs	BOS	W 119-81	240	119	55	25	7	6	42	91	46.2	16	45	35.6	19	21	90.5	59.4	15	40	14	23
8	76ers	35	4/28/2022	PHI	@	TOR	W 132-97	240	132	47	32	4	4	47	81	58.0	16	40	40.0	22	23	95.7	72.4	10	37	11	22
9	Jazz	35	5/30/1996	UTA	vs	SEA	W 118-83	240	118	37	35	15	7	44	73	60.3	6	15	40.0	24	30	80.0	68.4	7	30	11	25
10	Bullets	35	6/4/1978	WAS	vs	SEA	W 117-82	240	117	69	26	12	10	46	103	44.7				25	34	73.5	49.6	25	44	21	25
11	Pacers	34	4/27/2018	IND	vs	CLE	W 121-87	240	121	45	27	9	1	49	87	56.3	15	30	50.0	8	14	57.1	64.9	9	36	7	18
12	Celtics	31	5/15/1992	BOS	vs	CLE	W 122-91	240	122	44	41	11	6	52	88	59.1	0	6	0.0	18	22	81.8	62.4	12	32	9	17
13	Warriors	29	5/26/2018	GSW	vs	HOU	W 115-86	240	115	47	26	11	10	43	87	49.4	16	38	42.1	13	19	68.4	60.3	13	34	12	17
14	Spurs	28	5/15/2003	SAS	@	LAL	W 110-82	240	110	44	21	9	4	44	79	55.7	6	9	66.7	16	23	69.6	61.7	13	31	10	19
15	Jazz	28	5/19/1988	UTA	vs	LAL	W 108-80	240	108	41	27	11	4	38	80	47.5	3	4	75.0	29	36	80.6	56.3	11	30	10	22
16	Bucks	28	4/30/1978	MIL	vs	DEN	W 119-91	240	119	63	35	10	10	53	114	46.5				13	18	72.2	48.8	22	41	17	18
17	Hawks	28	4/12/1964	STL	vs	SFW	W 123-95	240	123	54	30			49	99	49.5				25	33	75.8	54.2				28
18	Mavericks	27	5/12/2022	DAL	vs	PHX	W 113-86	240	113	39	18	16	4	35	77	45.5	16	39	41.0	27	36	75.0	60.9	7	32	6	23
19	Suns	27	6/30/2021	PHX	@	LAC	W 130-103	240	130	47	27	5	4	53	94	56.4	17	31	54.8	7	11	63.6	65.8	10	37	9	21
20	Lakers	27	5/29/2009	LAL	@	DEN	W 119-92	240	119	38	28	6	4	43	75	57.3	9	16	56.3	24	24	100.0	69.5	9	29	13	19
21	Jazz	27	5/16/1996	UTA	vs	SAS	W 108-81	240	108	47	29	3	7	41	79	51.9	7	13	53.8	19	25	76.0	60.0	15	32	10	26
22	Pacers	27	6/2/1995	IND	vs	ORL	W 123-96	240	123	54	34	7	2	47	84	56.0	9	18	50.0	20	27	74.1	64.1	13	41	12	24
23	Cavaliers	26	5/27/2016	CLE	@	TOR	W 113-87	240	113	38	22	6	6	40	74	54.1	17	31	54.8	16	21	76.2	67.9	4	34	10	18
24	Heat	26	5/1/2009	MIA	vs	ATL	W 98-72	240	98	47	12	5	5	35	74	47.3	7	21	33.3	21	24	87.5	57.9	12	35	11	21
25	Nuggets	25	5/11/2023	DEN	@	PHX	W 125-100	240	125	41	24	10	3	44	82	53.7	8	22	36.4	29	31	93.5	65.3	7	34	10	22