Luka Dončić has the most points by an active guard in a game, with 73 points versus the Hawks on January 26, 2024.

Interpreted as:

highest points in a regular-season game current guards

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Luka Dončić L. Dončić	73	1/26/2024	DAL	@	ATL	45	10	7	1	0	25	33	75.8	8	13	61.5	15	16	93.8	91.2	0	10	4	1	+13
2	Damian Lillard D. Lillard	71	2/26/2023	POR	vs	HOU	39	6	6	0	0	22	38	57.9	13	22	59.1	14	14	100.0	80.4	1	5	2	0	+21
3	Donovan Mitchell D. Mitchell	71	1/2/2023	CLE	vs	CHI	50	8	11	0	1	22	34	64.7	7	15	46.7	20	25	80.0	78.9	3	5	4	3	+19
4	Devin Booker D. Booker	70	3/24/2017	PHX	@	BOS	45	8	6	3	1	21	40	52.5	4	11	36.4	24	26	92.3	68.0	2	6	5	3	-6
5	Devin Booker D. Booker	62	1/26/2024	PHX	@	IND	38	5	4	1	2	22	37	59.5	6	12	50.0	12	13	92.3	72.6	0	5	4	2	+1
6	Stephen Curry S. Curry	62	1/3/2021	GSW	vs	POR	36	5	4	0	0	18	31	58.1	8	16	50.0	18	19	94.7	78.8	1	4	5	0	+20
7	Jalen Brunson J. Brunson	61	3/29/2024	NYK	@	SAS	43	4	6	1	0	25	47	53.2	5	13	38.5	6	6	100.0	61.4	1	3	1	2	+20
8	Damian Lillard D. Lillard	61	8/11/2020	POR	@	DAL	41	5	8	1	0	17	32	53.1	9	17	52.9	18	18	100.0	76.4	2	3	3	2	+8
9	Damian Lillard D. Lillard	61	1/20/2020	POR	vs	GSW	45	10	7	1	0	17	37	45.9	11	20	55.0	16	16	100.0	69.3	0	10	2	1	+13
10	James Harden J. Harden	61	3/22/2019	HOU	vs	SAS	37	7	1	3	0	19	34	55.9	9	13	69.2	14	17	82.4	73.5	2	5	3	3	+18
11	James Harden J. Harden	61	1/23/2019	HOU	@	NYK	40	15	4	5	0	17	38	44.7	5	20	25.0	22	25	88.0	62.2	6	9	5	3	+19
12	De'Aaron Fox D. Fox	60	11/15/2024	SAC	vs	MIN	44	3	7	3	1	22	35	62.9	6	10	60.0	10	11	90.9	75.3	2	1	6	3	+1
13	Stephen Curry S. Curry	60	2/3/2024	GSW	@	ATL	41	6	4	0	1	22	38	57.9	10	23	43.5	6	6	100.0	73.8	1	5	2	1	-1
14	Damian Lillard D. Lillard	60	1/25/2023	POR	vs	UTA	40	7	8	3	0	21	29	72.4	9	15	60.0	9	10	90.0	89.8	0	7	4	1	+11
15	Luka Dončić L. Dončić	60	12/27/2022	DAL	vs	NYK	47	21	10	2	1	21	31	67.7	2	6	33.3	16	22	72.7	73.7	5	16	4	5	+7
16	Kyrie Irving K. Irving	60	3/15/2022	BKN	@	ORL	35	6	4	4	1	20	31	64.5	8	12	66.7	12	13	92.3	81.7	2	4	1	3	+36
17	Bradley Beal B. Beal	60	1/6/2021	WAS	@	PHI	38	7	5	1	0	20	35	57.1	7	10	70.0	13	15	86.7	72.1	4	3	4	3	-9
18	James Harden J. Harden	60	11/30/2019	HOU	vs	ATL	31	3	8	3	1	16	24	66.7	8	14	57.1	20	23	87.0	87.9	0	3	5	3	+50
19	Damian Lillard D. Lillard	60	11/8/2019	POR	vs	BKN	40	4	5	0	0	19	33	57.6	7	16	43.8	15	15	100.0	75.8	0	4	2	1	+4
20	James Harden J. Harden	60	1/30/2018	HOU	vs	ORL	46	10	11	4	1	19	30	63.3	5	14	35.7	17	18	94.4	79.1	2	8	5	2	+7
21	Klay Thompson K. Thompson	60	12/5/2016	GSW	vs	IND	29	2	1	0	0	21	33	63.6	8	14	57.1	10	11	90.9	79.3	0	2	0	0	+37
22	James Harden J. Harden	59	10/30/2019	HOU	@	WAS	38	3	9	1	0	18	32	56.3	6	14	42.9	17	18	94.4	73.9	1	2	4	3	+6
23	Devin Booker D. Booker	59	3/25/2019	PHX	@	UTA	41	4	4	1	0	19	34	55.9	5	8	62.5	16	17	94.1	71.1	1	3	6	5	-13
24	Damian Lillard D. Lillard	59	4/8/2017	POR	vs	UTA	42	6	5	1	1	18	34	52.9	9	14	64.3	14	16	87.5	71.9	0	6	0	0	+19
25	Devin Booker D. Booker	58	12/17/2022	PHX	vs	NOP	42	6	5	0	0	21	35	60.0	6	12	50.0	10	15	66.7	69.7	1	5	2	3	+11