LeBron James has put up the most career points per game versus Kobe Bryant, with 28.2 per game.

highest scoring average when going up against kobe bryant

Interpreted as:

highest scoring by a player average when going up against Kobe Bryant

NAME	PPG	GP	MPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
LeBron James	28.2	22	40.3	7.4	7.3	1.9	0.7	3.4	10.3	22.0	46.9	1.4	4.2	32.3	6.2	8.9	69.4	887	620	163	161	42	16	74	53	+70
Devin Booker	28.0	1	41.1	3.0	7.0	1.0	1.0	2.0	12.0	22.0	54.5	1.0	4.0	25.0	3.0	4.0	75.0	41	28	3	7	1	1	2	4	+22
Dominique Wilkins	28.0	3	32.7	10.0	2.3	1.0	0.7	2.3	9.3	18.3	50.9	3.3	7.0	47.6	6.0	7.7	78.3	98	84	30	7	3	2	7	5	+31
Kevin Durant	27.3	25	38.4	6.1	3.6	1.3	1.0	3.1	9.5	20.1	47.4	1.6	4.8	33.3	6.7	7.4	90.8	959	683	152	89	32	26	78	59	+101
Damian Lillard	26.6	7	36.8	2.9	8.0	1.1	0.3	2.7	9.6	20.6	46.5	3.0	7.6	39.6	4.4	4.7	93.9	257	186	20	56	8	2	19	12	+46
Allen Iverson	25.3	29	41.4	3.5	7.1	2.2	0.3	3.4	8.8	22.2	39.5	0.9	3.2	28.0	6.8	8.8	77.6	1,201	733	101	206	65	10	100	50	-48
CJ McCollum	25.0	3	33.4	3.0	3.0	1.3	0.7	2.0	10.7	18.0	59.3	3.7	6.7	55.0	0.0	0.0		100	75	9	9	4	2	6	7	+23
Mitch Richmond	24.9	8	39.6	3.1	3.4	1.4	0.0	3.1	8.4	19.3	43.5	2.0	5.5	36.4	6.1	6.9	89.1	317	199	25	27	11	0	25	21	-30
Karl Malone	24.6	25	36.4	8.1	3.4	0.9	0.6	2.9	8.1	16.5	48.9	0.1	0.2	40.0	8.3	10.0	83.5	910	614	202	84	23	14	73	81	+47
Kyrie Irving	24.5	6	35.1	2.5	6.8	1.7	0.3	3.2	10.2	18.7	54.5	2.0	4.8	41.4	2.2	2.7	81.3	210	147	15	41	10	2	19	17	+10
Michael Jordan	24.5	8	35.4	4.3	3.6	1.1	0.5	2.0	8.9	20.4	43.6	0.4	1.3	30.0	6.4	8.5	75.0	283	196	34	29	9	4	16	14	-29
Dwyane Wade	24.3	20	36.9	4.6	6.5	1.9	1.1	3.9	8.7	19.0	45.5	0.5	1.7	27.3	6.6	8.3	79.4	738	486	92	130	37	22	77	56	+52
Gilbert Arenas	24.2	16	38.2	4.8	4.9	1.1	0.3	3.4	7.4	18.3	40.6	2.1	6.8	31.5	7.2	8.6	83.9	610	387	76	78	17	5	54	49	-58
Brook Lopez	23.7	9	37.2	9.6	2.0	0.7	1.7	2.6	8.9	17.7	50.3	0.0	0.1	0.0	5.9	7.4	79.1	335	213	86	18	6	15	23	28	-95
Anthony Davis	23.6	7	31.5	8.6	0.7	1.7	2.3	1.4	9.9	15.4	63.9	0.0	0.3	0.0	3.9	5.6	69.2	221	165	60	5	12	16	10	19	+58
Derrick Rose	23.6	9	35.6	4.2	6.4	0.3	0.2	2.8	9.6	18.8	50.9	1.1	2.3	47.6	3.3	4.0	83.3	320	212	38	58	3	2	25	12	-10
Carmelo Anthony	23.5	29	36.0	6.3	3.3	1.2	0.4	3.2	8.6	18.7	46.1	0.8	2.8	27.5	5.5	6.5	84.6	1,045	681	182	96	36	12	94	98	-16
Stephon Marbury	23.2	26	38.7	3.0	8.3	1.2	0.1	3.6	8.0	18.4	43.6	1.5	4.4	34.8	5.6	7.2	77.1	1,006	603	78	215	30	3	93	69	-197
Robert Covington	23.0	1	34.5	5.0	4.0	0.0	2.0	3.0	8.0	16.0	50.0	5.0	11.0	45.5	2.0	4.0	50.0	34	23	5	4	0	2	3	3	+18
J.R. Bremer	23.0	1	41.0	5.0	4.0	0.0	0.0	3.0	7.0	17.0	41.2	4.0	12.0	33.3	5.0	6.0	83.3	41	23	5	4	0	0	3	2	-8
Stephen Curry	22.9	15	34.5	4.9	7.3	1.5	0.1	1.9	8.3	18.7	44.6	3.2	8.3	38.4	3.1	3.3	93.9	517	344	74	109	22	2	29	36	+31
Dirk Nowitzki	22.8	49	37.0	10.0	2.5	0.9	0.9	1.8	7.8	17.2	45.5	1.2	3.2	36.9	5.9	7.1	83.6	1,812	1,116	489	121	44	43	87	137	-1
Russell Westbrook	22.5	22	36.0	6.1	8.2	1.5	0.2	3.4	8.0	19.2	41.7	0.8	3.3	25.0	5.7	7.0	81.8	791	496	134	181	32	5	74	57	+92
Paul Pierce	22.5	26	36.0	5.2	3.8	1.3	0.3	3.3	7.4	16.3	45.2	2.1	5.2	40.7	5.6	7.2	77.5	937	584	136	98	35	9	87	88	+38
Charles Barkley	22.3	7	37.4	13.6	3.3	0.4	1.1	2.4	7.6	14.9	51.0	0.9	2.0	42.9	6.3	8.1	77.2	262	156	95	23	3	8	17	11	-27