LeBron James has scored the most career points per game versus Kobe Bryant, with 28.2 per game.

highest scoring average when going up against kobe bryant
Interpreted as:
highest scoring by a player average when going up against Kobe Bryant
JamesBookerWilkinsDurantLillardIversonMcCollumRichmondMaloneIrvingJordanWadeArenasLopezDavisRoseAnthonyMarburyCovingtonBremerCurryNowitzki28.228.028.027.326.625.325.024.924.624.524.524.324.223.723.623.623.523.223.023.022.922.8
NAMEGPPPGMPGRPGAPGSPGBPGTPGFGMFGAFG%3PM3PA3P%FTMFTAFT%MINPTSREBASTSTLBLKTOVPF+/-
LeBron JamesLeBron James2228.240.37.47.31.90.73.410.322.046.91.44.232.36.28.969.488762016316142167453+70
Devin BookerDevin Booker128.041.13.07.01.01.02.012.022.054.51.04.025.03.04.075.04128371124+22
Dominique WilkinsDominique Wilkins328.032.710.02.31.00.72.39.318.350.93.37.047.66.07.778.398843073275+31
Kevin DurantKevin Durant2527.338.46.13.61.31.03.19.520.147.41.64.833.36.77.490.89596831528932267859+101
Damian LillardDamian Lillard726.636.82.98.01.10.32.79.620.646.53.07.639.64.44.793.92571862056821912+46
Allen IversonAllen Iverson2925.341.43.57.12.20.33.48.822.239.50.93.228.06.88.877.61,201733101206651010050-48
CJ McCollumCJ McCollum325.033.43.03.01.30.72.010.718.059.33.76.755.00.00.010075994267+23
Mitch RichmondMitch Richmond824.939.63.13.41.40.03.18.419.343.52.05.536.46.16.989.131719925271102521-30
Karl MaloneKarl Malone2524.636.48.13.40.90.62.98.116.548.90.10.240.08.310.083.59106142028423147381+47
Kyrie IrvingKyrie Irving624.535.12.56.81.70.33.210.218.754.52.04.841.42.22.781.321014715411021917+10
Michael JordanMichael Jordan824.535.44.33.61.10.52.08.920.443.60.41.330.06.48.575.02831963429941614-29
Dwyane WadeDwyane Wade2024.336.94.66.51.91.13.98.719.045.50.51.727.36.68.379.47384869213037227756+52
Gilbert ArenasGilbert Arenas1624.238.24.84.91.10.33.47.418.340.62.16.831.57.28.683.961038776781755449-58
Brook LopezBrook Lopez923.737.29.62.00.71.72.68.917.750.30.00.10.05.97.479.133521386186152328-95
Anthony DavisAnthony Davis723.631.58.60.71.72.31.49.915.463.90.00.30.03.95.669.222116560512161019+58
Derrick RoseDerrick Rose923.635.64.26.40.30.22.89.618.850.91.12.347.63.34.083.33202123858322512-10
Carmelo AnthonyCarmelo Anthony2923.536.06.33.31.20.43.28.618.746.10.82.827.55.56.584.61,0456811829636129498-16
Stephon MarburyStephon Marbury2623.238.73.08.31.20.13.68.018.443.61.54.434.85.67.277.11,006603782153039369-197
Robert CovingtonRobert Covington123.034.55.04.00.02.03.08.016.050.05.011.045.52.04.050.03423540233+18
J.R. BremerJ.R. Bremer123.041.05.04.00.00.03.07.017.041.24.012.033.35.06.083.34123540032-8
Stephen CurryStephen Curry1522.934.54.97.31.50.11.98.318.744.63.28.338.43.13.393.9517344741092222936+31
Dirk NowitzkiDirk Nowitzki4922.837.010.02.50.90.91.87.817.245.51.23.236.95.97.183.61,8121,116489121444387137-1
Russell WestbrookRussell Westbrook2222.536.06.18.21.50.23.48.019.241.70.83.325.05.77.081.87914961341813257457+92
Paul PiercePaul Pierce2622.536.05.23.81.30.33.37.416.345.22.15.240.75.67.277.5937584136983598788+38
Charles BarkleyCharles Barkley722.337.413.63.30.41.12.47.614.951.00.92.042.96.38.177.22621569523381711-27