Stephen Curry has scored the most points in a game versus Deandre Ayton, with 50 points against the Suns on November 16, 2022.

Interpreted as:

highest scoring by a player regular-season games vs ayton

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Stephen Curry S. Curry	50	11/16/2022	GSW	@	PHX	36	9	6	0	1	17	28	60.7	7	11	63.6	9	9	100.0	78.2	0	9	3	2	-14
2	Giannis Antetokounmpo G. Antetokounmpo	47	2/10/2021	MIL	@	PHX	38	11	5	1	0	15	23	65.2	0	4	0.0	17	21	81.0	72.9	2	9	2	2	-3
3	Kyrie Irving K. Irving	46	12/28/2024	DAL	@	POR	39	2	2	2	1	16	26	61.5	5	12	41.7	9	9	100.0	76.8	1	1	4	1	-17
4	Jamal Murray J. Murray	46	12/29/2018	DEN	@	PHX	40	6	8	0	1	16	24	66.7	9	11	81.8	5	6	83.3	86.3	0	6	5	2	+6
5	Jalen Brunson J. Brunson	45	3/14/2024	NYK	@	POR	38	1	4	1	1	14	30	46.7	2	10	20.0	15	17	88.2	60.0	1	0	5	0	+17
6	Khris Middleton K. Middleton	44	3/6/2022	MIL	vs	PHX	36	8	5	1	0	16	27	59.3	5	9	55.6	7	7	100.0	73.1	0	8	3	2	+21
7	James Harden J. Harden	44	2/4/2019	HOU	@	PHX	38	8	6	3	1	15	26	57.7	5	13	38.5	9	11	81.8	71.3	0	8	3	3	+19
8	Cam Thomas C. Thomas	43	2/7/2023	BKN	vs	PHX	39	5	3	1	1	11	23	47.8	3	9	33.3	18	20	90.0	67.6	0	5	3	2	-4
9	Trae Young T. Young	43	2/3/2022	ATL	vs	PHX	36	0	5	1	0	16	25	64.0	6	10	60.0	5	7	71.4	76.6	0	0	4	1	+3
10	Gary Trent Jr. G. Trent Jr.	42	3/11/2022	TOR	@	PHX	40	8	1	0	0	13	21	61.9	8	11	72.7	8	8	100.0	85.6	1	7	2	2	+20
11	Anthony Davis A. Davis	42	5/9/2021	LAL	vs	PHX	41	12	5	3	3	13	27	48.1	1	5	20.0	15	17	88.2	60.9	3	9	3	1	+26
12	Anthony Edwards A. Edwards	42	3/18/2021	MIN	@	PHX	38	7	3	2	0	15	31	48.4	4	13	30.8	8	13	61.5	57.2	3	4	2	2	+9
13	Joel Embiid J. Embiid	42	1/2/2019	PHI	@	PHX	36	18	2	3	2	12	23	52.2	1	1	100.0	17	19	89.5	67.0	4	14	4	3	+6
14	Anthony Edwards A. Edwards	41	2/13/2024	MIN	@	POR	34	4	2	2	1	16	27	59.3	4	8	50.0	5	5	100.0	70.2	0	4	2	1	+16
15	Nikola Jokić N. Jokić	41	12/25/2022	DEN	vs	PHX	44	15	15	0	1	16	25	64.0	2	4	50.0	7	9	77.8	70.8	4	11	3	4	+12
16	Damian Lillard D. Lillard	41	10/21/2022	POR	vs	PHX	43	7	3	0	1	12	25	48.0	5	12	41.7	12	12	100.0	67.7	1	6	4	2	-2
17	Donovan Mitchell D. Mitchell	41	4/7/2021	UTA	@	PHX	41	8	3	0	0	16	35	45.7	4	12	33.3	5	7	71.4	53.8	0	8	1	5	-11
18	Karl-Anthony Towns K. Towns	41	3/18/2021	MIN	@	PHX	36	10	8	1	0	15	24	62.5	5	7	71.4	6	7	85.7	75.7	3	7	4	1	+4
19	James Harden J. Harden	41	3/15/2019	HOU	vs	PHX	42	9	11	6	3	12	25	48.0	3	11	27.3	14	17	82.4	63.1	0	9	6	3	+3
20	Nikola Jokić N. Jokić	40	2/10/2025	DEN	vs	POR	31	7	8	3	1	15	22	68.2	2	7	28.6	8	8	100.0	78.4	1	6	5	2	+22
21	Dejounte Murray D. Murray	40	3/13/2024	ATL	@	POR	43	4	3	2	1	15	29	51.7	6	13	46.2	4	5	80.0	64.1	1	3	5	5	-13
22	Kevin Durant K. Durant	40	12/19/2023	PHX	@	POR	38	4	5	2	0	16	28	57.1	1	3	33.3	7	8	87.5	63.5	0	4	5	1	+8
23	Luka Dončić L. Dončić	40	12/16/2023	DAL	@	POR	37	12	10	1	0	15	28	53.6	4	12	33.3	6	6	100.0	65.3	2	10	4	3	-4
24	Luka Dončić L. Dončić	40	8/2/2020	DAL	@	PHX	38	8	11	0	0	11	20	55.0	0	3	0.0	18	19	94.7	70.5	0	8	6	4	+3
25	Russell Westbrook R. Westbrook	40	12/28/2018	OKC	@	PHX	39	12	8	0	0	17	29	58.6	3	7	42.9	3	6	50.0	63.2	2	10	6	3	+6