Kawhi Leonard has averaged his most career points per game against the Spurs, with 24.9 per game.

kawhi leonard highest career ppg by opponent

OPP	PPG	GP	MPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
Spurs	24.9	14	31.7	4.9	5.2	2.1	0.4	1.7	9.4	17.6	53.4	1.6	3.9	40.7	4.4	4.8	92.5	444	348	68	73	30	6	24	22	+144
Wizards	24.4	17	32.3	7.3	2.9	1.9	0.4	1.5	9.2	17.6	52.5	1.9	5.2	36.0	4.0	4.8	82.9	549	414	124	50	32	6	25	27	+150
Bulls	23.8	17	35.2	6.5	2.8	1.9	0.5	1.4	8.9	16.8	53.3	1.7	4.1	42.0	4.2	4.8	87.8	599	405	111	48	32	9	24	18	+153
Cavaliers	23.5	19	32.7	7.4	3.0	1.4	1.1	2.2	8.4	15.7	53.5	1.8	4.9	37.6	4.8	5.6	85.0	621	446	141	57	27	20	41	31	+177
Heat	23.1	16	33.7	7.6	3.7	2.1	0.8	1.8	7.9	16.8	47.4	2.4	5.8	42.4	4.8	5.6	84.4	540	369	122	59	34	12	28	23	+174
Celtics	22.3	18	33.7	7.4	3.2	1.9	0.6	2.0	8.1	16.6	48.7	1.6	4.8	32.6	4.6	5.2	89.2	606	401	134	58	34	11	36	28	+126
Thunder	21.9	26	33.8	6.3	3.3	2.1	0.6	2.1	8.3	16.0	51.6	1.7	4.3	39.6	3.7	4.4	82.6	878	569	163	86	55	15	55	54	+138
Hawks	21.8	16	33.5	5.7	3.4	1.9	0.8	1.9	7.3	14.3	51.3	2.1	4.7	45.3	5.1	5.6	90.0	535	349	91	54	31	12	30	31	+105
Knicks	21.4	19	32.6	6.3	2.5	1.7	0.7	1.4	7.4	15.2	48.6	1.7	4.5	38.4	4.9	5.7	85.3	620	406	120	48	32	13	26	35	+44
Trail Blazers	20.9	29	31.7	6.1	3.1	1.8	0.6	1.7	7.6	14.5	52.4	1.8	4.1	44.9	3.9	4.4	88.4	920	607	176	90	52	18	49	50	+189
Nets	20.9	20	32.1	6.4	2.9	1.6	0.5	1.4	7.6	16.0	47.3	1.9	4.2	44.0	4.0	4.4	89.8	642	418	128	57	32	9	28	28	+197
Kings	20.7	29	32.9	5.8	3.1	2.0	0.8	1.4	7.5	14.7	51.3	1.8	4.6	38.3	3.9	4.5	87.7	954	601	169	89	57	24	42	49	+242
Pacers	20.6	15	33.8	6.4	2.9	1.6	0.3	1.5	8.2	15.7	52.1	1.3	3.9	34.5	2.9	3.5	81.1	507	309	96	44	24	5	22	30	+70
76ers	20.6	20	31.3	6.9	3.0	1.8	0.5	1.6	7.3	14.7	49.3	1.5	4.1	35.8	4.7	5.5	85.3	626	412	137	60	36	10	32	29	+151
Timberwolves	20.4	32	30.4	5.9	2.5	1.7	0.6	1.7	7.3	14.3	51.3	1.6	3.6	45.6	4.1	4.7	88.0	973	654	189	81	53	18	53	63	+234
Warriors	20.0	31	31.6	6.5	2.9	1.6	0.5	1.8	7.3	13.6	53.2	1.5	3.5	44.0	4.0	4.7	83.7	981	621	203	90	51	17	55	53	+139
Rockets	19.8	30	32.9	6.0	2.6	2.0	0.7	2.0	7.2	14.9	48.7	1.5	3.9	39.3	3.8	4.5	84.4	986	594	180	77	59	22	61	53	+124
Hornets	19.6	17	30.8	5.3	2.9	1.4	0.6	1.2	7.5	13.8	54.0	1.6	4.8	34.6	3.0	3.5	86.4	523	333	90	50	24	10	21	29	+173
Nuggets	19.2	33	31.4	6.3	3.5	1.8	1.1	1.6	7.3	14.2	51.2	1.3	3.5	37.6	3.4	3.8	88.8	1,038	635	208	115	61	36	54	55	+161
Pistons	19.1	16	30.2	5.5	3.1	1.8	0.8	1.9	6.7	14.3	46.9	1.8	4.4	41.4	3.9	4.6	84.9	483	305	88	50	29	12	31	33	+151
Lakers	18.9	34	30.1	6.7	3.2	1.5	0.7	1.6	6.7	13.3	50.7	1.7	4.4	38.3	3.8	4.5	83.1	1,025	643	229	110	51	25	55	71	+247
Pelicans	18.7	33	29.7	5.8	2.8	1.5	0.7	1.2	6.6	14.0	47.2	1.4	3.9	35.7	4.1	4.7	86.5	981	617	193	92	49	24	39	47	+82
Mavericks	18.6	34	31.6	7.1	2.9	1.6	0.4	1.2	6.6	14.2	46.2	1.5	4.2	35.7	4.0	4.6	87.7	1,075	633	242	97	55	15	40	42	+190
Magic	18.6	20	30.4	6.2	3.0	1.6	0.7	1.7	6.8	13.6	49.8	1.7	3.8	44.0	3.4	3.7	91.9	608	371	123	59	32	14	34	30	+101
Suns	18.5	31	31.2	6.7	3.0	1.8	0.5	1.8	6.5	14.1	46.6	1.3	3.4	37.1	4.1	4.8	86.5	967	573	209	92	56	15	55	48	+190