Klay Thompson has his most career points per game against the Pacers, with 23.8 per game.

klay thompson highest career ppg by opponent
INDCHIMINATLPORSACLALMILDETDALBOSPHXCHANOPNYKMIATORHOUDENORLOKCPHI23.822.422.021.420.720.520.420.420.420.320.120.120.120.019.919.819.319.119.118.718.418.4
OPPGPPPGMPGRPGAPGSPGBPGTPGFGMFGAFG%3PM3PA3P%FTMFTAFT%MINPTSREBASTSTLBLKTOVPF+/-
PacersPacers
1723.832.13.62.00.60.41.58.618.646.24.19.344.32.52.889.654640561341162616+125
BullsBulls
1722.431.73.92.20.70.61.58.117.446.63.99.143.52.22.684.4539381673712102628+82
TimberwolvesTimberwolves
3122.033.73.42.21.00.52.18.317.946.63.58.343.01.82.282.11,0466811046930176562+251
HawksHawks
1521.432.74.12.90.80.51.87.917.345.83.58.043.32.12.391.249032162441272734+110
Trail BlazersTrail Blazers
3120.732.03.42.00.90.51.47.416.445.42.96.743.13.03.586.99916431056327144472+183
KingsKings
3520.533.83.92.81.00.51.97.316.444.93.58.341.72.32.785.31,1837161369835196578+340
LakersLakers
3520.432.83.52.40.70.51.57.516.744.73.17.740.32.32.882.81,1477141218424195181+254
BucksBucks
1720.433.83.02.61.10.61.47.416.744.42.87.537.82.73.285.2575346514418112441+65
PistonsPistons
1720.432.53.22.11.10.21.67.814.952.42.65.844.42.12.585.755334654361842725+101
MavericksMavericks
3220.333.53.82.60.90.42.17.616.745.73.37.842.71.82.183.81,0726511218429136669+107
CelticsCeltics
1520.134.84.02.30.70.71.37.918.343.42.37.829.11.92.287.9522301603510101942+61
SunsSuns
3320.131.33.82.30.80.61.97.515.847.53.07.142.12.12.488.51,0326621257627196283+171
HornetsHornets
1720.133.13.23.00.70.61.87.616.246.73.57.745.01.41.685.7562341555112113141+145
PelicansPelicans
2720.034.53.52.51.00.62.27.415.946.72.86.642.42.32.981.8931540956726175955+245
KnicksKnicks
1819.931.03.91.90.70.31.37.716.446.83.27.741.31.41.689.755835970341262336+212
HeatHeat
1619.833.33.82.11.20.61.97.617.044.93.38.638.41.21.482.6533316613319103031+86
RaptorsRaptors
1619.332.83.62.40.80.71.77.215.446.63.37.345.31.61.696.2525308583912112744+80
RocketsRockets
3019.135.13.82.51.10.81.97.417.143.32.77.237.51.62.175.01,0535731157633245672+74
NuggetsNuggets
3019.131.93.62.40.80.51.67.416.146.23.07.141.61.31.679.29565731097123154847+155
MagicMagic
1718.732.23.62.60.70.51.57.415.647.03.57.546.90.50.588.954831862441292636+120
ThunderThunder
2918.431.43.32.21.00.61.66.815.145.12.66.938.02.22.781.8911535966330184775-12
76ers76ers
1518.431.72.72.01.10.32.36.915.843.93.27.344.01.31.495.247627640301643427+82
GrizzliesGrizzlies
3118.332.03.12.50.70.51.46.914.647.52.76.443.11.71.892.9993567957621164351+227
CavaliersCavaliers
1618.132.14.01.70.60.91.86.414.843.53.07.341.42.22.683.3514289642710152836+124
WizardsWizards
1718.033.22.82.31.10.51.56.916.242.43.18.138.41.11.290.556430648391882633+76
ClippersClippers
3417.832.43.02.41.00.51.76.615.044.02.56.140.82.12.583.51,1036051018034175871+175
JazzJazz
2917.832.93.41.50.80.41.46.714.645.82.65.845.01.82.185.0953515984423134051+127
NetsNets
1617.632.84.12.51.20.61.36.916.242.92.46.338.61.31.583.352628166401992134+98
SpursSpurs
2817.434.43.12.60.90.41.96.915.444.92.45.940.21.21.486.8964487887224125464-15