Wilt Chamberlain had the most games by a player 25 or older with 40+ points, with 204 games.

Interpreted as:

most 40 or more points regular-season game by a player after turning 25 years old

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	204	10,348		50.7	24.9				20.6	37.9	54.5				9.4	16.4	57.5	56.2					5,071					378
2	Michael Jordan M. Jordan	121	5,455	41.3	45.1	6.8	5.1	2.7	0.9	17.0	29.2	58.2	0.9	2.4	38.1	10.2	12.0	85.1	65.5	1.8	5.0	2.5	5,003	823	617	329	103	304	335	+232
3	James Harden J. Harden	102	4,639	39.5	45.5	7.4	8.3	2.1	0.8	13.3	26.5	50.4	5.7	13.0	43.5	13.2	15.0	87.7	68.8	1.2	6.2	4.9	4,028	755	844	213	77	497	304	+985
4	Kobe Bryant K. Bryant	95	4,292	42.6	45.2	6.2	4.2	1.7	0.5	15.2	29.7	51.2	3.0	6.9	43.2	11.7	13.7	85.2	63.1	1.2	5.0	3.2	4,047	593	398	165	48	301	267	+524
5	Elgin Baylor E. Baylor	86	3,899		45.3					17.1						11.2	13.8	80.9											301
6	Stephen Curry S. Curry	72	3,256	36.1	45.2	5.3	5.6	1.4	0.3	14.8	25.4	58.5	8.6	15.3	55.7	7.0	7.5	92.6	78.8	0.6	4.6	3.4	2,597	380	401	98	22	242	147	+868
7	George Gervin G. Gervin	66	2,899	40.0	43.9	5.0	2.9	1.4	0.9	17.3	29.3	59.0	0.3	0.9	35.8	9.1	10.7	84.8	64.6				2,639	331	191	90	57		175
8	Allen Iverson A. Iverson	63	2,808	45.1	44.6	4.2	6.4	2.6	0.2	15.5	30.5	50.9	1.8	4.6	40.1	11.7	13.8	85.0	61.0	0.8	3.3	3.7	2,842	263	406	162	12	231	130	+459
9	Damian Lillard D. Lillard	57	2,589	39.0	45.4	4.9	7.3	1.2	0.3	14.1	25.3	55.7	6.5	12.9	49.9	10.7	11.6	92.6	74.6	0.6	4.3	2.5	2,220	277	417	67	18	144	107	+396
10	Dominique Wilkins D. Wilkins	55	2,446	41.0	44.5	7.8	3.0	1.9	0.7	16.3	29.1	56.2	1.2	2.4	50.0	10.6	12.3	86.2	64.5	3.4	4.4	3.0	2,255	427	165	104	38	165	106
11	Oscar Robertson O. Robertson	55	2,355		42.8	8.2	10.7			14.7	26.3	56.0				13.3	14.9	89.5	65.1					451	590				184
12	Jerry West J. West	52	2,254		43.3					15.6						12.1	14.1	85.6
13	Russell Westbrook R. Westbrook	47	2,084	38.6	44.3	10.1	8.4	1.6	0.3	15.5	30.3	51.3	3.2	8.0	40.1	10.1	12.3	81.8	62.1	2.0	8.1	5.1	1,813	475	394	73	13	242	138	+48
14	Adrian Dantley A. Dantley	47	2,047	41.9	43.6	6.8	4.6		0.1	15.7	23.5	66.8	0.0			12.2	14.4	84.2	73.0				1,971	320	217		3		156
15	Kevin Durant K. Durant	45	1,984	40.3	44.1	7.4	5.5	1.1	1.1	15.1	26.5	57.0	4.2	8.6	48.7	9.7	11.0	88.5	70.4	0.6	6.8	4.0	1,815	334	248	50	50	181	103	+236
16	Larry Bird L. Bird	45	1,991	42.4	44.2	10.6	6.3	1.9		17.2	28.4	60.3	1.4	3.3	43.0	8.5	9.2	93.0	68.1				1,909	478	283	85			109
17	Giannis Antetokounmpo G. Antetokounmpo	44	1,988	36.5	45.2	13.3	5.4	1.1	1.1	17.0	25.6	66.3	1.2	3.3	36.8	10.1	14.2	71.1	71.0	3.0	10.3	3.3	1,604	586	239	49	50	145	121	+305
18	Joel Embiid J. Embiid	43	1,923	36.2	44.7	12.9	4.6	1.3	1.8	15.2	25.0	60.8	1.4	3.8	37.8	12.9	14.8	87.1	71.0	2.8	10.2	3.3	1,559	556	196	56	79	140	136	+487
19	LeBron James L. James	43	1,897	39.8	44.1	9.2	7.1	1.5	1.0	16.0	25.8	61.9	4.1	7.7	54.1	8.0	10.3	77.5	72.7	1.6	7.6	3.6	1,711	394	305	64	44	154	64	+383
20	Karl Malone K. Malone	41	1,771	41.0	43.2	11.5	3.1	1.6	1.1	15.5	23.8	65.1	0.1	0.3	23.1	12.2	15.2	80.4	71.0	2.7	8.8	3.6	1,683	472	128	64	47	147	138	+103
21	Bernard King B. King	38	1,704	41.2	44.8	7.3	3.7			17.0	28.3	60.2	0.1	0.3	23.1	10.7	13.7	78.4	65.4	2.6	4.7		1,565	278	141				128
22	Rick Barry R. Barry	35	1,565	41.7	44.7	6.2	6.6	2.9		18.6	33.2	56.1				7.5	8.1	92.6	60.8			3.2	1,458	216	232	100		19	106
23	Bob Pettit B. Pettit	34	1,512		44.5					16.4						11.6	14.2	82.0											117
24	Alex English A. English	33	1,425	40.9	43.2	6.2	5.0			17.5	27.8	63.0	0.0	0.1	33.3	8.1	9.1	88.4	67.8			3.1	1,351	203	166			101	112
25	Kareem Abdul-Jabbar K. Abdul-Jabbar	32	1,370	44.3	42.8	15.3	4.1		3.6	17.6	28.3	62.3	0.0	0.0		7.6	10.1	74.9	65.4				1,417	490	130		89		104