Since 2019-20, Damian Lillard has the most games with 50+ points, with 10 games.

Interpreted as:

most 50 or more point regular-season games by a player since 2020

NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	REB	AST	STL	BLK	TOV	PF	+/-
Damian Lillard	10	565	40.1	56.5	5.1	7.9	1.0	0.0	2.7	17.2	29.7	57.9	8.1	15.5	52.3	14.0	14.6	95.9	401	51	79	10	0	27	12	+106
Joel Embiid	8	435	35.3	54.4	13.5	4.9	1.0	2.5	2.9	19.1	28.6	66.8	0.9	2.5	35.0	15.3	17.0	89.7	283	108	39	8	20	23	22	+122
Luka Doncic	7	388	41.5	55.4	9.7	8.9	2.4	0.9	4.3	18.6	28.3	65.7	6.0	11.7	51.2	12.3	15.6	78.9	291	68	62	17	6	30	20	+60
Stephen Curry	7	382	37.2	54.6	5.3	5.6	1.0	0.4	3.1	17.7	29.7	59.6	9.0	17.1	52.5	10.1	10.7	94.7	260	37	39	7	3	22	10	+48
Giannis Antetokounmpo	7	377	36.0	53.9	13.7	4.1	1.1	0.1	3.7	19.1	29.0	66.0	1.4	4.3	33.3	14.1	18.6	76.2	252	96	29	8	1	26	19	+107
Devin Booker	5	275	37.6	55.0	4.4	5.8	0.4	0.6	2.4	20.0	31.0	64.5	6.4	11.6	55.2	8.6	10.2	84.3	188	22	29	2	3	12	11	+55
Jayson Tatum	5	269	40.1	53.8	8.4	4.8	0.0	0.4	2.4	17.0	28.6	59.4	7.0	11.6	60.3	12.8	14.0	91.4	201	42	24	0	2	12	13	+69
James Harden	5	278	38.8	55.6	4.6	7.6	2.4	1.2	4.6	16.8	31.6	53.2	7.6	16.2	46.9	14.4	15.2	94.7	194	23	38	12	6	23	18	+84
Bradley Beal	4	218	39.5	54.5	4.8	3.3	1.0	0.8	5.3	18.3	31.5	57.9	5.8	10.3	56.1	12.3	14.0	87.5	158	19	13	4	3	21	13	-9
Kyrie Irving	4	214	35.6	53.5	5.5	5.5	1.5	0.8	2.0	17.8	26.5	67.0	7.8	11.8	66.0	10.3	11.5	89.1	142	22	22	6	3	8	14	+88
Tyrese Maxey	3	153	44.8	51.0	4.7	4.3	0.7	1.3	1.0	18.7	33.3	56.0	5.3	10.0	53.3	8.3	8.7	96.2	134	14	13	2	4	3	8	+29
Kevin Durant	3	159	42.2	53.0	6.7	7.0	1.3	0.7	4.7	18.0	32.0	56.3	5.7	11.0	51.5	11.3	12.7	89.5	127	20	21	4	2	14	9	+37
Jalen Brunson	2	111	39.3	55.5	5.0	7.5	3.0	0.0	1.5	21.0	35.0	60.0	7.0	11.0	63.6	6.5	7.5	86.7	79	10	15	6	0	3	2	+27
Karl-Anthony Towns	2	122	37.0	61.0	12.5	2.5	0.5	0.0	6.5	20.0	33.0	60.6	8.5	13.0	65.4	12.5	15.0	83.3	74	25	5	1	0	13	7	+16
LeBron James	2	106	37.1	53.0	8.5	4.5	0.0	1.0	3.5	18.5	28.0	66.1	6.0	10.0	60.0	10.0	10.5	95.2	74	17	9	0	2	7	3	+35
Zach LaVine	2	101	38.1	50.5	6.5	2.5	0.5	0.0	3.5	18.5	32.0	57.8	7.0	12.5	56.0	6.5	8.0	81.3	76	13	5	1	0	7	3	-11
Trae Young	2	106	38.5	53.0	3.0	11.0	1.0	0.5	5.5	14.5	25.5	56.9	7.5	13.5	55.6	16.5	17.0	97.1	77	6	22	2	1	11	5	+20
Anthony Davis	2	105	38.4	52.5	12.0	3.5	2.0	2.0	1.5	21.0	29.5	71.2	1.0	2.5	40.0	9.5	9.5	100.0	77	24	7	4	4	3	2	+36
Anthony Edwards	1	51	37.6	51.0	6.0	7.0	0.0	0.0	2.0	17.0	29.0	58.6	6.0	13.0	46.2	11.0	11.0	100.0	38	6	7	0	0	2	0	+6
Malachi Flynn	1	50	34.1	50.0	6.0	5.0	3.0	0.0	4.0	18.0	25.0	72.0	5.0	9.0	55.6	9.0	12.0	75.0	34	6	5	3	0	4	2	+14
Jrue Holiday	1	51	32.5	51.0	8.0	8.0	1.0	1.0	6.0	20.0	30.0	66.7	3.0	6.0	50.0	8.0	10.0	80.0	32	8	8	1	1	6	3	+26
Julius Randle	1	57	36.9	57.0	4.0	1.0	0.0	0.0	4.0	19.0	29.0	65.5	8.0	14.0	57.1	11.0	13.0	84.6	37	4	1	0	0	4	4	-6
Klay Thompson	1	54	45.9	54.0	8.0	3.0	0.0	1.0	3.0	21.0	39.0	53.8	10.0	21.0	47.6	2.0	2.0	100.0	46	8	3	0	1	3	4	+13
Donovan Mitchell	1	71	49.8	71.0	8.0	11.0	0.0	1.0	4.0	22.0	34.0	64.7	7.0	15.0	46.7	20.0	25.0	80.0	50	8	11	0	1	4	3	+19
Pascal Siakam	1	52	41.2	52.0	9.0	7.0	1.0	0.0	1.0	17.0	25.0	68.0	2.0	6.0	33.3	16.0	18.0	88.9	41	9	7	1	0	1	2	+8