Michael Jordan had the most games by a guard with 40+ points, with 165 games.

Interpreted as:

most regular-season games with 40 or more points as a guard

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	Michael Jordan M. Jordan	165	7,463	41.3	45.2	6.4	5.2	2.8	1.2	16.8	29.4	57.3	0.7	2.0	34.7	10.9	12.6	86.3	64.7	1.9	4.5	2.8	6,819	1,055	850	470	190	458	476	+128
2	Kobe Bryant K. Bryant	121	5,441	42.8	45.0	6.1	4.2	1.8	0.6	15.3	30.0	51.2	2.9	6.5	44.2	11.4	13.3	85.7	62.8	1.2	4.9	3.3	5,176	737	508	213	73	394	333	+752
3	James Harden J. Harden	107	4,854	39.5	45.4	7.4	8.1	2.1	0.7	13.3	26.2	50.8	5.6	12.8	44.2	13.1	14.9	87.9	69.2	1.2	6.2	4.8	4,226	788	869	228	79	516	318	+1074
4	Allen Iverson A. Iverson	79	3,507	44.9	44.4	4.3	6.3	2.3	0.2	15.5	30.5	51.0	2.0	5.0	40.6	11.3	13.6	83.4	60.9	1.0	3.3	3.7	3,546	339	494	185	14	294	177	+443
5	Oscar Robertson O. Robertson	77	3,288		42.7	9.3	10.9			15.0						12.7	14.4	88.2						718	836				268
6	Stephen Curry S. Curry	74	3,352	36.4	45.3	5.3	5.6	1.4	0.3	14.9	25.4	58.5	8.5	15.2	56.1	7.0	7.6	92.9	78.8	0.7	4.7	3.4	2,693	395	416	103	23	248	150	+870
7	George Gervin G. Gervin	66	2,899	40.0	43.9	5.0	2.9	1.4	0.9	17.3	29.3	59.0	0.3	0.9	35.8	9.1	10.7	84.8	64.6				2,639	331	191	90	57		175
8	Jerry West J. West	66	2,891		43.8					15.8						12.2	14.4	84.8
9	Damian Lillard D. Lillard	60	2,713	39.3	45.2	4.9	7.3	1.2	0.3	14.1	25.3	55.7	6.5	12.9	50.2	10.6	11.5	92.6	74.5	0.6	4.3	2.6	2,356	293	438	71	20	156	115	+423
10	Luka Dončić L. Dončić	51	2,270	38.8	44.5	9.7	9.1	1.5	0.5	15.0	26.4	57.0	4.9	10.8	45.7	9.5	12.0	79.3	70.3	0.9	8.8	3.8	1,977	495	465	79	23	195	139	+433
11	Russell Westbrook R. Westbrook	50	2,212	39.0	44.2	9.8	8.3	1.6	0.3	15.5	30.1	51.6	3.1	7.8	40.2	10.1	12.2	82.6	62.4	2.0	7.9	5.0	1,949	491	417	78	15	251	141	+74
12	Devin Booker D. Booker	37	1,711	38.0	46.2	5.3	5.9	1.2	0.5	16.4	27.5	59.8	3.9	8.5	46.3	9.4	10.7	88.4	71.9	0.8	4.5	3.5	1,405	197	219	45	18	130	107	+295
13	Kyrie Irving K. Irving	37	1,657	39.4	44.8	4.7	5.5	1.8	0.5	15.9	26.8	59.4	5.7	10.0	56.9	7.2	7.9	91.2	73.9	0.8	3.9	2.7	1,458	173	203	66	19	100	98	+292
14	Tracy McGrady T. McGrady	37	1,640	41.6	44.3	7.4	5.0	1.7	0.9	15.8	29.6	53.3	3.5	7.5	46.7	9.3	12.1	77.4	63.6	1.8	5.6	2.9	1,538	275	186	62	33	107	68	+146
15	Nate Archibald N. Archibald	37	1,634		44.2	3.2		3.2		16.3	28.8	56.4				11.6	13.4	86.9	63.6					120		16
16	Pete Maravich P. Maravich	35	1,554		44.4					16.7						11.0	12.7	86.7
17	Trae Young T. Young	34	1,487	38.1	43.7	4.2	9.1	1.1	0.1	13.7	25.6	53.6	5.2	11.0	47.1	11.1	12.6	88.1	70.2	0.8	3.4	4.8	1,294	142	310	39	5	164	57	+156
18	Dwyane Wade D. Wade	34	1,467	41.9	43.1	6.2	6.2	2.5	1.4	15.0	26.4	56.8	1.6	3.8	43.4	11.4	14.1	81.2	66.1	1.4	4.8	3.9	1,426	212	212	84	48	134	81	+212
19	Donovan Mitchell D. Mitchell	31	1,349	39.1	43.5	5.6	4.9	1.4	0.4	15.0	27.8	54.0	5.2	11.6	44.6	8.3	9.5	87.5	68.1	1.1	4.5	3.2	1,211	173	153	44	11	98	74	+280
20	Bradley Beal B. Beal	31	1,378	40.8	44.5	4.8	5.5	1.2	0.4	15.8	28.0	56.5	4.6	9.4	48.6	8.3	9.6	86.2	69.0	1.4	3.4	3.1	1,265	148	169	36	12	96	80	+29
21	Gilbert Arenas G. Arenas	29	1,277	42.7	44.0	4.0	5.7	1.9	0.2	13.7	25.5	53.7	4.7	9.6	48.6	12.0	14.4	83.1	69.1	1.0	3.0	3.9	1,238	117	165	56	7	114	97	+162
22	Shai Gilgeous-Alexander S. Gilgeous-Alexander	28	1,226	36.9	43.8	5.6	5.9	1.9	1.1	14.6	24.8	58.9	2.4	5.1	46.2	12.2	13.5	90.5	71.3	0.9	4.8	2.3	1,032	157	164	54	32	64	72	+377
23	DeMar DeRozan D. DeRozan	26	1,116	40.3	42.9	6.1	4.5	1.2	0.4	15.3	26.6	57.4	1.5	3.5	41.3	10.9	12.7	85.8	66.6	1.1	5.0	2.3	1,047	159	116	32	10	61	58	+211
24	Anthony Edwards A. Edwards	24	1,054	38.7	43.9	6.0	3.9	1.6	0.8	14.8	26.9	55.1	5.8	12.2	47.8	8.4	10.3	82.1	69.9	1.0	5.0	3.5	928	144	94	39	20	83	49	+227
25	Zach LaVine Z. LaVine	24	1,038	39.0	43.3	5.3	3.5	1.4	0.3	15.6	25.9	60.4	6.7	11.6	57.9	5.3	6.3	83.6	75.4	0.8	4.5	3.5	936	127	83	33	7	83	56	+140