Since 1999-00, the Washington Wizards have lost the most games by a team, with 1,180 losses.

Interpreted as:

most regular-season losses by an NBA team since 2000

TEAM	L	GP	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF
Washington Wizards	1,180	2,014	241.8	101.8	42.2	22.1	7.7	4.7	14.5	38.1	84.0	45.4	7.3	20.5	35.3	18.3	24.2	75.7	486,885	205,074	85,053	44,579	15,496	9,446	29,286	42,831
New York Knicks	1,140	2,008	242.0	100.3	42.6	20.8	7.1	4.2	14.3	37.3	83.1	44.8	8.2	23.0	35.7	17.6	22.9	76.7	485,945	201,459	85,484	41,773	14,251	8,453	28,734	43,301
Minnesota Timberwolves	1,121	2,006	241.7	102.4	42.7	23.3	7.6	4.9	14.4	38.6	84.4	45.7	7.1	20.1	35.2	18.3	23.6	77.4	484,840	205,478	85,683	46,704	15,226	9,787	28,837	41,874
Brooklyn Nets	1,105	2,014	241.8	100.4	42.1	22.6	7.3	4.6	14.4	37.0	82.6	44.8	8.1	23.0	35.4	18.2	23.9	76.2	486,935	202,184	84,794	45,464	14,644	9,233	29,074	42,597
Atlanta Hawks	1,103	2,009	241.8	101.5	42.4	22.5	7.6	4.8	14.9	37.8	83.3	45.4	8.0	22.3	35.6	17.9	23.3	76.7	485,860	203,905	85,109	45,284	15,320	9,670	29,835	41,215
Orlando Magic	1,097	2,015	241.5	100.8	42.8	21.5	7.3	4.8	14.6	37.5	83.0	45.2	8.1	23.0	35.4	17.6	23.7	74.2	486,550	203,046	86,163	43,302	14,801	9,612	29,383	41,736
Sacramento Kings	1,085	2,014	241.8	104.7	42.6	22.8	8.0	4.3	14.6	39.0	85.0	45.9	8.0	22.3	36.0	18.6	24.4	76.2	487,060	210,766	85,865	45,934	16,049	8,629	29,428	41,744
Detroit Pistons	1,084	2,008	241.8	99.2	42.5	21.7	7.3	4.9	13.9	37.0	82.9	44.7	7.5	21.3	35.0	17.7	23.8	74.2	485,470	199,280	85,297	43,516	14,591	9,745	27,908	41,307
Chicago Bulls	1,084	2,007	242.1	99.3	43.4	22.5	7.4	4.9	14.8	37.4	83.6	44.7	7.2	20.1	35.8	17.3	22.8	76.0	485,905	199,221	87,107	45,243	14,834	9,845	29,709	41,798
Memphis Grizzlies	1,073	2,015	241.8	100.1	42.2	22.0	8.1	5.2	14.6	37.6	83.0	45.3	7.0	20.1	34.9	17.9	23.7	75.3	487,250	201,622	85,068	44,343	16,406	10,504	29,418	42,145
Charlotte Hornets	1,072	1,843	242.0	99.8	42.3	22.5	7.5	5.1	13.9	36.9	83.3	44.4	7.7	21.9	35.1	18.3	24.4	75.1	446,045	183,988	77,921	41,472	13,753	9,357	25,594	36,660
Cleveland Cavaliers	1,039	2,007	241.7	100.7	43.0	22.2	7.3	4.6	14.5	37.5	82.8	45.3	7.8	21.8	35.9	17.9	23.9	74.9	485,155	202,142	86,201	44,548	14,554	9,195	29,179	40,907
Philadelphia 76ers	1,030	2,015	241.7	100.6	42.8	22.4	8.4	5.0	14.8	37.6	83.0	45.2	7.0	20.1	35.0	18.5	24.4	75.7	487,050	202,734	86,185	45,069	16,891	9,983	29,765	41,893
L.A. Clippers	1,011	2,014	241.4	102.3	42.7	22.3	7.3	5.2	14.6	37.8	82.3	46.0	7.7	21.3	36.3	18.9	25.0	75.4	486,185	205,986	85,995	44,887	14,762	10,491	29,328	42,254
Toronto Raptors	1,008	2,014	241.9	102.1	42.0	22.2	7.6	4.9	13.5	37.9	83.8	45.3	8.2	22.7	36.0	18.1	23.3	77.7	487,135	205,623	84,556	44,733	15,273	9,814	27,204	42,971
Milwaukee Bucks	994	2,015	241.8	103.3	43.0	23.0	7.6	4.7	14.2	38.7	84.2	45.9	8.3	22.8	36.3	17.7	23.2	76.1	487,200	208,217	86,553	46,357	15,229	9,554	28,599	42,276
Golden State Warriors	986	2,007	241.4	106.4	43.9	24.6	8.2	5.3	14.9	39.7	86.4	45.9	9.4	25.2	37.1	17.7	23.3	76.0	484,530	213,595	88,028	49,302	16,423	10,591	30,002	43,380
Portland Trail Blazers	983	2,016	241.8	101.3	42.5	21.6	7.1	4.8	14.1	37.7	83.1	45.4	8.3	22.9	36.1	17.6	22.7	77.4	487,390	204,248	85,726	43,591	14,298	9,739	28,391	41,104
Phoenix Suns	955	2,015	241.5	105.4	42.8	23.6	7.7	4.9	14.8	39.7	85.1	46.6	8.5	23.3	36.4	17.6	22.9	77.1	486,650	212,430	86,165	47,515	15,465	9,967	29,847	42,813
Indiana Pacers	951	2,014	241.6	102.1	42.9	22.6	7.6	5.3	14.5	37.9	83.4	45.4	8.1	22.4	36.0	18.3	23.6	77.5	486,635	205,646	86,410	45,459	15,379	10,641	29,229	43,093
Houston Rockets	942	2,014	241.8	103.3	43.3	21.6	7.7	4.8	15.0	37.4	83.1	45.0	9.7	27.6	35.3	18.7	24.8	75.6	487,085	207,997	87,183	43,473	15,410	9,664	30,118	41,413
Oklahoma City Thunder	940	2,014	241.8	104.0	43.4	21.7	7.9	5.1	14.6	38.6	84.3	45.8	8.1	22.8	35.4	18.7	24.2	77.3	486,960	209,365	87,508	43,673	15,864	10,262	29,434	42,379
New Orleans Pelicans	937	1,768	241.8	101.8	42.9	22.7	7.6	4.7	14.0	38.3	83.8	45.7	7.8	22.0	35.7	17.4	22.8	76.5	427,495	179,983	75,852	40,137	13,401	8,252	24,790	35,800
Denver Nuggets	923	2,015	241.5	104.9	43.7	24.2	7.9	5.3	14.8	39.1	84.6	46.2	7.9	22.2	35.4	18.9	25.1	75.2	486,700	211,291	87,968	48,798	16,011	10,723	29,849	42,910
Utah Jazz	917	2,014	241.5	101.9	42.9	23.4	7.6	5.3	15.1	37.6	81.1	46.3	7.4	20.5	35.8	19.3	25.5	75.8	486,410	205,170	86,343	47,129	15,229	10,655	30,493	44,397