Wilt Chamberlain has posted the most points by a center in a game, with 100 points against the Knicks on March 2, 1962.

Interpreted as:

most points ever by a center in a regular-season game

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	100	3/2/1962	PHI		NYK	48	25	2			36	63	57.1				28	32	87.5	64.9				2
2	Wilt Chamberlain W. Chamberlain	78	12/8/1961	PHI	vs	LAL	63	43	1			31	62	50.0				16	31	51.6	51.6				4
3	Wilt Chamberlain W. Chamberlain	73	11/16/1962	SFW	@	NYK	48	14	1			29	43	67.4				15	19	78.9	71.1				0
4	Wilt Chamberlain W. Chamberlain	73	1/13/1962	PHI	vs	CHI	48	36	0			29	48	60.4				15	25	60.0	61.9				2
5	Wilt Chamberlain W. Chamberlain	72	11/3/1962	SFW	@	LAL	48	18	1			29	48	60.4				14	18	77.8	64.4				0
6	David Robinson D. Robinson	71	4/24/1994	SAS	@	LAC	44	14	5	0	2	26	41	63.4	1	2	50.0	18	25	72.0	68.3	4	10	8	2
7	Joel Embiid J. Embiid	70	1/22/2024	PHI	vs	SAS	37	18	5	1	1	24	41	58.5	1	2	50.0	21	23	91.3	68.5	9	9	1	2	+11
8	Wilt Chamberlain W. Chamberlain	70	3/10/1963	SFW	@	SYR	48	18	3			27	38	71.1				16	22	72.7	73.4				2
9	Wilt Chamberlain W. Chamberlain	68	12/16/1967	PHI	@	CHI	48	34	2			30	40	75.0				8	22	36.4	68.4				1
10	Wilt Chamberlain W. Chamberlain	67	1/11/1963	SFW	vs	LAL	48	25	1			28	47	59.6				11	17	64.7	61.5				1
11	Wilt Chamberlain W. Chamberlain	67	2/25/1962	PHI	vs	NYK	48	21	1			25	38	65.8				17	22	77.3	70.3				1
12	Wilt Chamberlain W. Chamberlain	67	2/17/1962	PHI	@	STL	48	28	2			26	44	59.1				15	20	75.0	63.4				1
13	Wilt Chamberlain W. Chamberlain	67	3/9/1961	PHI	vs	NYK	48	31	1			27	37	73.0				13	17	76.5	75.3				1
14	Wilt Chamberlain W. Chamberlain	66	2/9/1969	LAL	vs	PHX	48	27	4			29	35	82.9				8	18	44.4	76.9				1
15	Wilt Chamberlain W. Chamberlain	65	2/7/1966	PHI	vs	LAL	47	29	2			28	43	65.1				9	20	45.0	62.7				3
16	Wilt Chamberlain W. Chamberlain	65	2/27/1962	PHI	@	STL	48	23	2			25	43	58.1				15	20	75.0	62.7				3
17	Wilt Chamberlain W. Chamberlain	65	2/13/1962	PHI	@	CIN	48	22	4			24	40	60.0				17	30	56.7	61.1				3
18	Wilt Chamberlain W. Chamberlain	63	11/26/1964	SFW	@	PHI	48	32	3			27	58	46.6				9	20	45.0	47.2				2
19	Wilt Chamberlain W. Chamberlain	63	12/14/1962	SFW	vs	LAL	48	30	1			24	41	58.5				15	20	75.0	63.3				4
20	Karl-Anthony Towns K. Towns	62	1/22/2024	MIN	vs	CHA	38	8	2	0	0	21	35	60.0	10	15	66.7	10	14	71.4	75.3	3	5	7	2	0
21	Wilt Chamberlain W. Chamberlain	62	3/3/1966	PHI	vs	SFW	48	37	3			26	39	66.7				10	19	52.6	65.5				2
22	Wilt Chamberlain W. Chamberlain	62	11/15/1964	SFW	@	CIN	48	22	1			26	44	59.1				10	21	47.6	58.2				1
23	Wilt Chamberlain W. Chamberlain	62	1/29/1963	SFW	@	NYK	48	12	0			27	44	61.4				8	17	47.1	60.2				1
24	Wilt Chamberlain W. Chamberlain	62	1/21/1962	PHI		SYR	53	23	3			25	42	59.5				12	17	70.6	62.7				1
25	Wilt Chamberlain W. Chamberlain	62	1/17/1962	PHI		STL	53	23	4			24	48	50.0				14	20	70.0	54.6				3

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DATE	MATCHUP			TIME (ET)
Wed 12/31	GSW	@	CHA	1:00 PM
Fri 1/2	OKC	@	GSW	10:00 PM
Sat 1/3	UTA	@	GSW	10:00 PM
Mon 1/5	GSW	@	LAC	10:00 PM
Wed 1/7	MIL	@	GSW	10:00 PM

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2	Knicks	23	9	.719	1.5
3	Celtics	20	12	.625	4.5
4	Raptors	20	14	.588	5.5
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DATE	MATCHUP			SCORE
Fri 11/28	NOP	@	GSW	96-104
Fri 11/28	DEN	@	PHX	130-112
Fri 11/28	DAL	@	LAC	114-110
Sat 11/29	HOU	@	UTA	129-101
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DATE	MATCHUP			TIME (ET)
Wed 12/31	GSW	@	CHA	1:00 PM
Wed 12/31	ORL	@	IND	3:00 PM
Wed 12/31	MIN	@	ATL	3:00 PM
Wed 12/31	PHX	@	CLE	3:30 PM
Wed 12/31	NYK	@	SAS	7:00 PM

Wilt Chamberlain has posted the most points by a center in a game, with 100 points against the Knicks on March 2, 1962.

Interpreted as:

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