LeBron James had his most points in a regular-season or postseason game versus the Celtics in Game 6 of the 2018 Eastern Conference Finals, with 46 points.
| NAME | PTS | DATE | TM | OPP | MIN | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. James | 46 | 5/25/2018 |  CLE | vs |  BOS | 46 | 11 | 9 | 3 | 1 | 17 | 33 | 51.5 | 5 | 7 | 71.4 | 7 | 11 | 63.6 | 60.8 | 3 | 8 | 3 | 2 | +15 |
| 2 |  | L. James | 45 | 6/7/2012 |  MIA | @ | BOS | 45 | 15 | 5 | 0 | 0 | 19 | 26 | 73.1 | 2 | 4 | 50.0 | 5 | 9 | 55.6 | 75.1 | 2 | 13 | 4 | 3 | +22 |
| 3 | | L. James | 45 | 5/18/2008 | CLE | @ | BOS | 47 | 5 | 6 | 2 | 0 | 14 | 29 | 48.3 | 3 | 11 | 27.3 | 14 | 19 | 73.7 | 60.2 | 1 | 4 | 2 | 4 | 0 |
| 4 | | L. James | 44 | 5/21/2018 | CLE | vs | BOS | 42 | 5 | 3 | 2 | 0 | 17 | 28 | 60.7 | 1 | 4 | 25.0 | 9 | 13 | 69.2 | 65.2 | 1 | 4 | 7 | 3 | +9 |
| 5 | | L. James | 43 | 2/15/2006 | CLE | @ | BOS | 54 | 12 | 11 | 2 | 4 | 16 | 32 | 50.0 | 0 | 5 | 0.0 | 11 | 15 | 73.3 | 55.7 | 1 | 11 | 2 | 5 | +5 |
| 6 | | L. James | 42 | 5/15/2018 | CLE | @ | BOS | 39 | 10 | 12 | 0 | 1 | 16 | 29 | 55.2 | 5 | 11 | 45.5 | 5 | 10 | 50.0 | 62.9 | 1 | 9 | 6 | 3 | -9 |
| 7 | | L. James | 42 | 4/4/2010 | CLE | @ | BOS | 45 | 7 | 9 | 1 | 1 | 14 | 31 | 45.2 | 0 | 9 | 0.0 | 14 | 22 | 63.6 | 51.6 | 1 | 6 | 3 | 0 | -1 |
| 8 |  | L. James | 41 | 1/28/2023 |  LAL | @ | BOS | 44 | 9 | 8 | 0 | 0 | 15 | 30 | 50.0 | 6 | 12 | 50.0 | 5 | 6 | 83.3 | 62.8 | 1 | 8 | 2 | 2 | +1 |
| 9 | | L. James | 41 | 11/14/2014 | CLE | @ | BOS | 41 | 4 | 7 | 0 | 1 | 16 | 27 | 59.3 | 3 | 8 | 37.5 | 6 | 9 | 66.7 | 66.2 | 0 | 4 | 3 | 4 | +10 |
| 10 | | L. James | 38 | 5/17/2017 | CLE | @ | BOS | 42 | 9 | 7 | 2 | 0 | 14 | 24 | 58.3 | 1 | 6 | 16.7 | 9 | 11 | 81.8 | 65.9 | 2 | 7 | 2 | 2 | +17 |
| 11 | | L. James | 38 | 5/7/2010 | CLE | @ | BOS | 39 | 8 | 7 | 1 | 2 | 14 | 22 | 63.6 | 2 | 3 | 66.7 | 8 | 9 | 88.9 | 73.2 | 2 | 6 | 1 | 1 | +30 |
| 12 | | L. James | 38 | 10/27/2009 | CLE | vs | BOS | 45 | 4 | 8 | 2 | 4 | 12 | 22 | 54.5 | 4 | 9 | 44.4 | 10 | 13 | 76.9 | 68.5 | 0 | 4 | 5 | 4 | 0 |
| 13 | | L. James | 38 | 1/9/2009 | CLE | vs | BOS | 36 | 7 | 6 | 4 | 3 | 13 | 25 | 52.0 | 3 | 7 | 42.9 | 9 | 9 | 100.0 | 65.6 | 1 | 6 | 3 | 2 | +20 |
| 14 | | L. James | 38 | 11/27/2007 | CLE | vs | BOS | 46 | 4 | 13 | 2 | 2 | 11 | 25 | 44.0 | 2 | 8 | 25.0 | 14 | 15 | 93.3 | 60.1 | 0 | 4 | 3 | 2 | +14 |
| 15 | | L. James | 38 | 11/11/2006 | CLE | vs | BOS | 44 | 8 | 5 | 3 | 0 | 9 | 17 | 52.9 | 1 | 4 | 25.0 | 19 | 23 | 82.6 | 70.1 | 1 | 7 | 2 | 4 | +6 |
| 16 | | L. James | 37 | 3/18/2013 | MIA | @ | BOS | 42 | 7 | 12 | 2 | 2 | 16 | 29 | 55.2 | 1 | 4 | 25.0 | 4 | 6 | 66.7 | 58.5 | 1 | 6 | 5 | 3 | +13 |
| 17 | | L. James | 37 | 12/13/2003 | CLE | vs | BOS | 45 | 3 | 4 | 0 | 0 | 10 | 20 | 50.0 | 1 | 5 | 20.0 | 16 | 18 | 88.9 | 66.3 | 1 | 2 | 2 | 2 | -2 |
| 18 | | L. James | 36 | 4/5/2017 | CLE | @ | BOS | 39 | 10 | 6 | 1 | 2 | 14 | 22 | 63.6 | 1 | 4 | 25.0 | 7 | 7 | 100.0 | 71.8 | 2 | 8 | 3 | 3 | +32 |
| 19 | | L. James | 36 | 4/10/2012 | MIA | vs | BOS | 41 | 7 | 7 | 1 | 1 | 11 | 23 | 47.8 | 1 | 3 | 33.3 | 13 | 14 | 92.9 | 61.7 | 5 | 2 | 2 | 3 | -6 |
| 20 | | L. James | 36 | 2/25/2010 | CLE | @ | BOS | 36 | 7 | 9 | 0 | 0 | 11 | 23 | 47.8 | 3 | 6 | 50.0 | 11 | 15 | 73.3 | 60.8 | 1 | 6 | 2 | 2 | +9 |
| 21 | | L. James | 36 | 3/24/2006 | CLE | vs | BOS | 45 | 7 | 8 | 2 | 3 | 13 | 26 | 50.0 | 4 | 8 | 50.0 | 6 | 8 | 75.0 | 61.0 | 3 | 4 | 0 | 2 | +8 |
| 22 | | L. James | 36 | 11/22/2005 | CLE | vs | BOS | 41 | 5 | 4 | 2 | 2 | 13 | 20 | 65.0 | 1 | 3 | 33.3 | 9 | 11 | 81.8 | 72.5 | 0 | 5 | 1 | 4 | +14 |
| 23 | | L. James | 35 | 5/27/2018 | CLE | @ | BOS | 48 | 15 | 9 | 0 | 2 | 12 | 24 | 50.0 | 3 | 8 | 37.5 | 8 | 11 | 72.7 | 60.7 | 0 | 15 | 8 | 4 | +8 |
| 24 | | L. James | 35 | 5/25/2017 | CLE | @ | BOS | 35 | 8 | 8 | 3 | 1 | 13 | 18 | 72.2 | 4 | 7 | 57.1 | 5 | 8 | 62.5 | 81.3 | 1 | 7 | 2 | 4 | +36 |
| 25 | | L. James | 35 | 5/9/2011 | MIA | @ | BOS | 50 | 14 | 3 | 3 | 0 | 12 | 28 | 42.9 | 2 | 6 | 33.3 | 9 | 9 | 100.0 | 54.8 | 3 | 11 | 5 | 3 | +7 |
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