D'Angelo Russell has averaged 19.3 points, 5.2 assists and 3.3 rebounds in 12 games against the Cavaliers between January 1, 2019 and October 9, 2025.
| NAME | DATE | TM | OPP | MIN | PTS | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Russell | 2/13/2019 |  BKN | @ |  CLE | 43 | 36 | 7 | 8 | 0 | 0 | 13 | 30 | 43.3 | 5 | 15 | 33.3 | 5 | 6 | 83.3 | 55.1 | 1 | 6 | 7 | 5 | +7 |
| 2 | | D. Russell | 3/6/2019 | BKN | vs | CLE | 32 | 25 | 4 | 5 | 3 | 0 | 9 | 20 | 45.0 | 4 | 8 | 50.0 | 3 | 6 | 50.0 | 55.2 | 0 | 4 | 5 | 4 | -4 |
| 3 |  | D. Russell | 2/1/2020 |  GSW | @ | CLE | 29 | 19 | 7 | 8 | 0 | 0 | 6 | 14 | 42.9 | 6 | 11 | 54.5 | 1 | 2 | 50.0 | 63.8 | 1 | 6 | 2 | 1 | +18 |
| 4 |  | D. Russell | 1/31/2021 |  MIN | vs | CLE | 31 | 19 | 1 | 5 | 0 | 0 | 7 | 18 | 38.9 | 5 | 10 | 50.0 | 0 | 0 | 52.8 | 1 | 0 | 2 | 2 | +1 | |
| 5 | | D. Russell | 2/1/2021 | MIN | @ | CLE | 29 | 18 | 2 | 4 | 1 | 0 | 7 | 19 | 36.8 | 3 | 9 | 33.3 | 1 | 2 | 50.0 | 45.3 | 0 | 2 | 0 | 1 | -4 |
| 6 | | D. Russell | 2/28/2022 | MIN | @ | CLE | 35 | 25 | 4 | 3 | 1 | 1 | 8 | 17 | 47.1 | 4 | 8 | 50.0 | 5 | 6 | 83.3 | 63.6 | 1 | 3 | 4 | 3 | +7 |
| 7 | | D. Russell | 11/13/2022 | MIN | @ | CLE | 35 | 30 | 2 | 11 | 1 | 0 | 11 | 13 | 84.6 | 4 | 5 | 80.0 | 4 | 6 | 66.7 | 95.9 | 0 | 2 | 2 | 2 | +19 |
| 8 | | D. Russell | 1/14/2023 | MIN | vs | CLE | 21 | 9 | 0 | 1 | 0 | 0 | 4 | 8 | 50.0 | 1 | 3 | 33.3 | 0 | 0 | 56.3 | 0 | 0 | 1 | 2 | -6 | |
| 9 |  | D. Russell | 11/25/2023 |  LAL | @ | CLE | 32 | 10 | 5 | 5 | 2 | 0 | 4 | 12 | 33.3 | 2 | 6 | 33.3 | 0 | 0 | 41.7 | 0 | 5 | 4 | 3 | +3 | |
| 10 | | D. Russell | 4/6/2024 | LAL | vs | CLE | 31 | 28 | 5 | 2 | 1 | 1 | 11 | 17 | 64.7 | 6 | 12 | 50.0 | 0 | 0 | 82.4 | 0 | 5 | 6 | 2 | +21 | |
| 11 | | D. Russell | 10/30/2024 | LAL | @ | CLE | 24 | 10 | 3 | 5 | 0 | 0 | 2 | 7 | 28.6 | 0 | 3 | 0.0 | 6 | 6 | 100.0 | 51.9 | 1 | 2 | 0 | 0 | -8 |
| 12 | | D. Russell | 2/20/2025 | BKN | vs | CLE | 18 | 3 | 0 | 5 | 0 | 0 | 1 | 7 | 14.3 | 1 | 6 | 16.7 | 0 | 0 | 21.4 | 0 | 0 | 1 | 2 | +9 | |
| Average | 29.9 | 19.3 | 3.3 | 5.2 | 0.8 | 0.2 | 6.9 | 15.2 | 45.6 | 3.4 | 8.0 | 42.7 | 2.1 | 2.8 | 73.5 | 58.9 | 0.4 | 2.9 | 2.8 | 2.3 | 5.3 | ||||||
| Total | 359 | 232 | 40 | 62 | 9 | 2 | 83 | 182 | 45.6 | 41 | 96 | 42.7 | 25 | 34 | 73.5 | 58.9 | 5 | 35 | 34 | 27 | +63 |
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