largest point difference in an nba game 2022-202:

The Memphis Grizzlies had the highest point differential by a team in a game in 2021-22, with a 73 point differential against the Thunder on December 2, 2021.

Interpreted as:

largest point difference in an NBA regular-season game 2022-202:

	TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Grizzlies	73	12/2/2021	MEM	vs	OKC	W 152-79	240	152	53	41	16	9	60	96	62.5	19	36	52.8	13	18	72.2	73.1	14	39	10	15
2	Celtics	53	1/25/2022	BOS	vs	SAC	W 128-75	240	128	67	32	6	6	51	103	49.5	20	45	44.4	6	7	85.7	60.3	17	50	11	12
3	Clippers	50	4/10/2022	LAC	vs	OKC	W 138-88	240	138	57	34	4	8	54	97	55.7	18	35	51.4	12	14	85.7	66.9	12	45	9	11
4	Mavericks	50	4/8/2022	DAL	vs	POR	W 128-78	240	128	51	25	9	5	42	79	53.2	20	45	44.4	24	31	77.4	69.1	9	42	14	19
5	Celtics	48	2/15/2022	BOS	@	PHI	W 135-87	240	135	51	28	2	10	46	82	56.1	25	45	55.6	18	22	81.8	73.6	7	44	9	25
6	Bulls	46	1/11/2022	CHI	vs	DET	W 133-87	240	133	61	33	13	4	50	92	54.3	18	34	52.9	15	19	78.9	66.3	14	47	17	23
7	Cavaliers	45	12/26/2021	CLE	vs	TOR	W 144-99	240	144	52	39	12	5	56	106	52.8	22	52	42.3	10	12	83.3	64.7	13	39	12	17
8	Timberwolves	43	3/7/2022	MIN	vs	POR	W 124-81	240	124	67	21	10	9	38	92	41.3	13	43	30.2	35	44	79.5	55.7	19	48	20	25
9	Timberwolves	43	11/20/2021	MIN	vs	MEM	W 138-95	240	138	50	28	12	6	49	91	53.8	20	41	48.8	20	28	71.4	66.8	18	32	13	26
10	Celtics	42	4/3/2022	BOS	vs	WAS	W 144-102	240	144	39	39	6	5	56	91	61.5	23	44	52.3	9	13	69.2	74.4	7	32	7	20
11	Nets	42	3/15/2022	BKN	@	ORL	W 150-108	240	150	48	35	9	4	53	88	60.2	16	27	59.3	28	34	82.4	72.8	7	41	12	23
12	Warriors	42	1/14/2022	GSW	@	CHI	W 138-96	240	138	47	39	12	5	53	94	56.4	19	42	45.2	13	17	76.5	68.0	9	38	7	17
13	Heat	42	10/21/2021	MIA	vs	MIL	W 137-95	240	137	58	28	8	2	51	96	53.1	15	35	42.9	20	31	64.5	62.5	11	47	11	26
14	Warriors	41	11/5/2021	GSW	vs	NOP	W 126-85	240	126	49	36	10	4	47	91	51.6	20	50	40.0	12	14	85.7	64.8	9	40	11	16
15	Raptors	40	3/26/2022	TOR	vs	IND	W 131-91	240	131	42	34	9	3	51	84	60.7	15	32	46.9	14	19	73.7	70.9	9	33	6	16
16	Jazz	38	3/9/2022	UTA	vs	POR	W 123-85	240	123	50	31	3	5	42	81	51.9	17	46	37.0	22	27	81.5	66.2	6	44	9	23
17	Warriors	38	1/25/2022	GSW	vs	DAL	W 130-92	240	130	58	31	8	2	49	92	53.3	17	43	39.5	15	18	83.3	65.1	12	46	14	17
18	Spurs	37	3/23/2022	SAS	@	POR	W 133-96	240	133	53	34	8	11	46	94	48.9	19	44	43.2	22	24	91.7	63.6	14	39	13	13
19	Timberwolves	37	3/4/2022	MIN	@	OKC	W 138-101	240	138	41	35	17	7	49	91	53.8	22	47	46.8	18	23	78.3	68.2	7	34	17	17
20	Warriors	37	2/24/2022	GSW	@	POR	W 132-95	240	132	46	36	10	7	45	88	51.1	15	41	36.6	27	32	84.4	64.7	10	36	12	23
21	Nuggets	37	1/15/2022	DEN	vs	LAL	W 133-96	240	133	51	35	9	2	47	91	51.6	23	40	57.5	16	17	94.1	67.5	9	42	6	17
22	Jazz	36	4/6/2022	UTA	vs	OKC	W 137-101	240	137	55	29	7	10	49	84	58.3	15	36	41.7	24	32	75.0	69.8	16	39	11	13
23	Raptors	36	2/28/2022	TOR	@	BKN	W 133-97	240	133	47	35	17	5	51	99	51.5	18	38	47.4	13	22	59.1	61.2	16	31	12	20
24	Nuggets	36	1/30/2022	DEN	@	MIL	W 136-100	240	136	41	39	8	3	53	88	60.2	23	43	53.5	7	10	70.0	73.6	6	35	9	15
25	Celtics	35	2/8/2022	BOS	@	BKN	W 126-91	240	126	52	32	6	8	50	91	54.9	14	40	35.0	12	16	75.0	64.3	11	41	13	14