Joel Embiid had the most games with 40+ points in 2021-22, with 13 games.

Interpreted as:

most 40 or more point games by a player in 2021-22 season

NAME	GP	PTS	SEASON	TM	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	REB	AST	STL	BLK	TOV	PF	+/-
Joel Embiid	13	553	2021-22	PHI	36.5	42.5	13.8	4.3	1.1	1.9	3.8	14.1	23.7	59.4	1.9	3.7	52.1	12.5	15.2	82.2	475	180	56	14	25	49	43	+155
Trae Young	10	443	2021-22	ATL	35.6	44.3	3.5	9.1	1.0	0.1	4.2	14.7	24.5	60.0	5.4	10.6	50.9	9.5	10.3	92.2	356	35	91	10	1	42	16	+110
Giannis Antetokounmpo	10	432	2021-22	MIL	36.8	43.2	13.4	5.6	1.0	1.3	3.6	15.3	21.8	70.2	1.8	4.0	45.0	10.8	14.4	75.0	368	134	56	10	13	36	31	+53
Stephen Curry	7	308	2021-22	GSW	36.1	44.0	5.7	5.9	1.7	0.6	3.3	14.6	24.9	58.6	8.1	15.3	53.3	6.7	6.9	97.9	253	40	41	12	4	23	9	+118
Luka Doncic	6	267	2021-22	DAL	40.5	44.5	11.5	8.0	1.2	0.3	5.3	15.5	29.5	52.5	5.5	12.3	44.6	8.0	10.7	75.0	243	69	48	7	2	32	15	+36
Ja Morant	6	264	2021-22	MEM	36.5	44.0	5.7	6.0	1.3	0.5	4.0	14.8	25.7	57.8	3.7	5.5	66.7	10.7	13.3	80.0	219	34	36	8	3	24	13	+57
DeMar DeRozan	5	216	2021-22	CHI	38.8	43.2	5.0	5.8	1.0	0.0	3.0	16.4	25.4	64.6	0.4	1.2	33.3	10.0	11.0	90.9	194	25	29	5	0	15	16	+17
Jayson Tatum	5	232	2021-22	BOS	38.2	46.4	6.4	5.0	1.2	0.4	2.0	16.0	27.0	59.3	7.2	12.6	57.1	7.2	8.2	87.8	191	32	25	6	2	10	12	+104
Kyrie Irving	4	195	2021-22	BKN	39.1	48.8	3.5	6.0	2.0	1.0	2.8	15.8	25.3	62.4	7.8	12.8	60.8	9.5	10.3	92.7	157	14	24	8	4	11	14	+66
Devin Booker	4	181	2021-22	PHX	37.7	45.3	6.3	6.0	1.8	0.3	2.0	16.8	28.5	58.8	3.0	7.5	40.0	8.8	10.3	85.4	151	25	24	7	1	8	12	+32
Kevin Durant	4	200	2021-22	BKN	41.5	50.0	7.8	6.5	1.3	1.3	4.0	17.0	29.8	57.1	5.3	9.8	53.8	10.8	11.8	91.5	166	31	26	5	5	16	11	+55
Nikola Jokic	3	136	2021-22	DEN	41.4	45.3	14.3	8.3	2.7	1.7	4.0	16.7	27.3	61.0	2.3	5.0	46.7	9.7	11.3	85.3	124	43	25	8	5	12	10	+26
LeBron James	3	149	2021-22	LAL	34.5	49.7	10.3	4.3	0.7	1.3	2.3	17.7	27.3	64.6	5.7	10.0	56.7	8.7	10.0	86.7	104	31	13	2	4	7	4	+53
Anthony Edwards	3	137	2021-22	MIN	39.9	45.7	7.0	4.3	2.0	1.0	3.0	15.3	27.3	56.1	6.0	13.3	45.0	9.0	12.3	73.0	120	21	13	6	3	9	7	+29
De'Aaron Fox	2	85	2021-22	SAC	40.9	42.5	2.5	8.5	1.5	0.5	1.5	16.5	31.5	52.4	4.0	7.5	53.3	5.5	6.0	91.7	82	5	17	3	1	3	8	-3
Gary Trent Jr.	2	84	2021-22	TOR	38.7	42.0	4.5	2.5	2.0	0.0	2.0	14.0	23.5	59.6	7.0	12.0	58.3	7.0	7.5	93.3	77	9	5	4	0	4	4	+29
Karl-Anthony Towns	2	100	2021-22	MIN	34.6	50.0	13.0	5.0	1.0	0.0	4.0	17.0	28.0	60.7	5.5	8.5	64.7	10.5	12.0	87.5	69	26	10	2	0	8	7	+43
Paul George	2	83	2021-22	LAC	34.2	41.5	9.0	3.0	1.5	0.5	3.5	15.0	24.5	61.2	5.5	10.5	52.4	6.0	7.5	80.0	68	18	6	3	1	7	4	-24
Jaylen Brown	2	96	2021-22	BOS	46.1	48.0	10.0	5.0	2.0	1.5	5.5	17.5	29.5	59.3	6.5	12.0	54.2	6.5	8.0	81.3	92	20	10	4	3	11	9	+26
Victor Oladipo	1	40	2021-22	MIA	35.5	40.0	10.0	7.0	2.0	0.0	4.0	13.0	22.0	59.1	5.0	11.0	45.5	9.0	11.0	81.8	36	10	7	2	0	4	2	-4
Klay Thompson	1	41	2021-22	GSW	30.9	41.0	3.0	2.0	0.0	0.0	3.0	16.0	29.0	55.2	7.0	14.0	50.0	2.0	3.0	66.7	31	3	2	0	0	3	2	+25
Malik Monk	1	41	2021-22	LAL	35.2	41.0	4.0	1.0	0.0	0.0	3.0	14.0	25.0	56.0	7.0	14.0	50.0	6.0	6.0	100.0	35	4	1	0	0	3	2	-5
Obi Toppin	1	42	2021-22	NYK	40.1	42.0	10.0	3.0	0.0	1.0	2.0	16.0	28.0	57.1	6.0	14.0	42.9	4.0	4.0	100.0	40	10	3	0	1	2	1	+8
Jalen Green	1	41	2021-22	HOU	39.5	41.0	1.0	3.0	1.0	0.0	0.0	14.0	26.0	53.8	4.0	11.0	36.4	9.0	11.0	81.8	40	1	3	1	0	0	1	0
Talen Horton-Tucker	1	40	2021-22	LAL	37.0	40.0	3.0	3.0	4.0	0.0	2.0	15.0	28.0	53.6	2.0	6.0	33.3	8.0	9.0	88.9	37	3	3	4	0	2	2	-5