James Harden has the most games in double-doubles with 40+ points, with 46 games.

Interpreted as:

most regular-season games with 40+ points and dd2 by a player

	NAME	GP	PTS	DD2	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	James Harden J. Harden	46	2,059	46	40.5	44.8	9.6	10.4	2.2	0.8	13.1	26.5	49.3	5.3	13.0	40.7	13.3	15.4	86.7	67.3	1.5	8.2	5.2	1,864	442	479	102	38	237	133	+456
2	Giannis Antetokounmpo G. Antetokounmpo	44	2,005	44	36.5	45.6	14.0	5.5	1.2	1.2	16.6	25.3	65.7	1.3	3.5	38.8	11.0	15.2	72.5	71.3	3.0	11.1	3.3	1,607	617	243	51	51	143	125	+353
3	Joel Embiid J. Embiid	44	1,961	44	36.1	44.6	13.9	4.5	1.3	2.1	15.1	25.0	60.6	1.5	3.8	38.7	12.8	14.9	86.2	70.7	3.0	10.9	3.3	1,590	611	196	55	91	144	143	+515
4	Shaquille O'Neal S. O'Neal	43	1,846	43	40.8	42.9	14.4	2.4	0.9	2.2	17.0	25.9	65.4	0.0	0.0	0.0	9.0	15.1	59.7	65.9	5.4	9.0	2.7	1,754	621	104	37	96	115	133	+239
5	Michael Jordan M. Jordan	39	1,805	39	42.5	46.3	10.6	6.4	2.8	1.0	17.1	29.8	57.5	1.1	2.4	43.6	11.0	12.7	86.5	65.5	2.9	7.7	2.6	1,659	414	249	111	39	103	124	+50
6	Anthony Davis A. Davis	38	1,672	38	39.8	44.0	15.1	2.9	1.8	2.1	15.8	27.0	58.6	1.4	3.3	44.4	10.9	12.6	86.0	67.5	4.0	11.1	2.1	1,513	573	111	69	80	79	96	+359
7	Luka Dončić L. Dončić	35	1,552	35	39.4	44.3	10.5	9.9	1.6	0.4	14.9	26.9	55.4	4.9	10.9	45.0	9.7	11.9	80.9	69.0	1.1	9.4	4.1	1,378	366	345	56	15	145	95	+255
8	LeBron James L. James	35	1,555	35	42.7	44.4	10.9	8.4	1.7	1.2	15.6	27.1	57.6	3.3	7.1	46.4	10.0	12.6	79.3	68.2	2.1	8.9	3.8	1,494	383	294	58	42	134	65	+272
9	Russell Westbrook R. Westbrook	33	1,448	33	39.0	43.9	11.6	9.3	1.6	0.2	15.2	29.7	51.2	3.4	8.3	40.5	10.1	12.2	82.6	62.5	2.3	9.3	5.4	1,288	383	307	52	8	178	102	+21
10	Karl Malone K. Malone	29	1,263	29	41.4	43.6	13.8	2.9	1.4	1.1	15.6	23.8	65.3	0.0	0.2	16.7	12.4	15.7	79.3	70.9	3.5	10.3	3.9	1,201	400	85	42	33	112	100	+21
11	Hakeem Olajuwon H. Olajuwon	29	1,247	29	43.4	43.0	13.8	3.4	2.0	3.5	16.5	27.5	60.0	0.1	0.3	25.0	9.9	12.3	80.6	65.3	3.9	9.9	3.9	1,258	401	100	57	101	112	100	+18
12	Larry Bird L. Bird	29	1,282	29	43.0	44.2	12.1	6.6	1.7	1.0	16.9	28.3	59.6	1.5	3.6	41.9	8.9	9.6	93.1	67.9	2.2	9.9	3.2	1,248	351	190	49	28	93	69
13	Kevin Durant K. Durant	26	1,119	26	42.2	43.0	11.4	5.2	1.1	1.1	14.4	25.6	56.2	3.7	7.5	49.5	10.6	11.8	89.9	70.0	1.2	10.2	3.7	1,097	296	136	29	29	96	64	+154
14	Nikola Jokić N. Jokić	23	1,023	23	39.8	44.5	13.8	8.6	1.9	1.1	17.0	27.9	60.7	2.4	5.7	42.7	8.1	10.0	81.0	68.8	3.7	10.0	3.3	915	317	198	43	25	76	71	+243
15	Patrick Ewing P. Ewing	22	951	22	40.9	43.2	14.4	1.8	1.2	3.4	17.4	27.1	64.1	0.0	0.1	33.3	8.5	10.4	81.2	68.2	4.3	10.0	3.6	899	316	39	26	74	79	83
16	Damian Lillard D. Lillard	18	798	18	40.1	44.3	5.4	10.9	1.3	0.2	13.2	24.6	53.8	6.9	13.4	51.2	11.0	11.9	92.5	74.4	0.5	4.9	2.1	721	97	196	23	4	38	33	+120
17	Kobe Bryant K. Bryant	18	804	18	45.3	44.7	9.2	6.8	1.4	0.7	14.6	28.3	51.4	3.8	7.4	50.7	11.8	14.1	83.8	64.7	1.5	7.7	4.2	815	166	122	26	13	76	49	+67
18	Charles Barkley C. Barkley	17	723	17	43.0	42.5	15.1	3.2	2.4	0.8	14.8	22.8	64.9	1.2	3.2	37.0	11.7	14.8	79.0	72.5	6.0	9.1	4.3	731	256	55	40	14	73	57	+16
19	Karl-Anthony Towns K. Towns	15	666	15	38.4	44.4	14.4	3.7	1.3	0.6	16.0	26.4	60.6	3.7	6.7	55.0	8.7	10.6	82.4	71.5	3.5	10.9	3.4	577	216	55	20	9	51	54	+95
20	Tracy McGrady T. McGrady	15	674	15	43.8	44.9	10.7	5.7	1.9	1.1	15.5	29.3	53.0	3.5	6.9	50.5	10.4	14.1	73.9	63.2	2.3	8.4	3.5	657	160	85	29	17	52	28	+164
21	David Robinson D. Robinson	15	671	15	43.2	44.7	14.0	3.6	2.0	4.9	15.7	25.9	60.8	0.1	0.3	40.0	13.1	16.2	81.1	67.8	4.1	9.9	3.5	648	210	54	30	73	52	44
22	Dominique Wilkins D. Wilkins	14	615	14	41.4	43.9	12.1	3.0	1.9	0.4	15.9	28.1	56.5	1.3	2.6	48.6	10.9	12.7	86.0	65.2	5.9	6.2	2.5	579	170	42	26	6	35	21
23	Trae Young T. Young	13	580	13	40.3	44.6	5.3	12.6	1.0	0.3	13.9	26.0	53.6	5.0	10.8	46.4	11.8	13.6	86.4	69.7	1.2	4.2	5.1	524	69	164	13	4	66	24	+86
24	DeMarcus Cousins D. Cousins	13	574	13	39.5	44.2	15.8	4.0	1.5	1.5	14.8	26.3	56.4	2.5	5.5	45.1	12.0	15.0	80.0	67.1	3.9	11.8	4.5	514	205	52	20	20	58	57	+89
25	Allen Iverson A. Iverson	13	552	13	44.1	42.5	4.1	10.3	1.9	0.2	15.0	29.4	51.0	1.5	4.4	35.1	10.9	13.1	83.5	60.4	0.6	3.5	3.3	574	53	134	25	3	43	19	+188