Between the 2009-10 and 2012-13 seasons, Dwyane Wade put up his most points in a regular-season or postseason game in Game 4 of the 2010 First Round against the Celtics, with 46 points.
| NAME | PTS | DATE | TM | OPP | MIN | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Wade | 46 | 4/25/2010 | vs | 43 | 5 | 5 | 2 | 0 | 16 | 24 | 66.7 | 5 | 7 | 71.4 | 9 | 14 | 64.3 | 76.3 | 0 | 5 | 6 | 4 | +7 | ||
| 2 | | D. Wade | 45 | 12/29/2010 | @ | 38 | 7 | 1 | 2 | 0 | 17 | 24 | 70.8 | 1 | 3 | 33.3 | 10 | 10 | 100.0 | 79.2 | 0 | 7 | 6 | 3 | +2 | ||
| 3 | | D. Wade | 44 | 1/6/2010 | vs | 43 | 5 | 7 | 3 | 1 | 15 | 34 | 44.1 | 3 | 7 | 42.9 | 11 | 16 | 68.8 | 53.6 | 5 | 0 | 2 | 5 | -11 | ||
| 4 | | D. Wade | 43 | 4/2/2010 | @ | 44 | 9 | 6 | 3 | 3 | 14 | 22 | 63.6 | 2 | 3 | 66.7 | 13 | 17 | 76.5 | 72.9 | 2 | 7 | 5 | 1 | +20 | ||
| 5 | | D. Wade | 41 | 5/24/2012 | @ | 39 | 10 | 3 | 2 | 0 | 17 | 25 | 68.0 | 0 | 0 | 7 | 8 | 87.5 | 71.9 | 2 | 8 | 5 | 3 | +4 | |||
| 6 | | D. Wade | 41 | 2/25/2011 | vs | 40 | 5 | 2 | 2 | 0 | 18 | 27 | 66.7 | 2 | 3 | 66.7 | 3 | 9 | 33.3 | 66.2 | 0 | 5 | 2 | 1 | +10 | ||
| 7 | | D. Wade | 41 | 2/15/2011 | @ | 42 | 12 | 3 | 2 | 0 | 16 | 29 | 55.2 | 1 | 4 | 25.0 | 8 | 10 | 80.0 | 61.4 | 0 | 12 | 2 | 2 | +16 | ||
| 8 | | D. Wade | 41 | 11/10/2009 | vs | 38 | 5 | 5 | 3 | 1 | 14 | 29 | 48.3 | 1 | 3 | 33.3 | 12 | 13 | 92.3 | 59.0 | 2 | 3 | 2 | 2 | +16 | ||
| 9 | | D. Wade | 40 | 12/28/2010 | vs | 38 | 9 | 2 | 2 | 1 | 13 | 28 | 46.4 | 1 | 7 | 14.3 | 13 | 16 | 81.3 | 57.1 | 2 | 7 | 0 | 2 | +11 | ||
| 10 | | D. Wade | 40 | 11/4/2009 | @ | 43 | 4 | 5 | 1 | 2 | 14 | 26 | 53.8 | 2 | 5 | 40.0 | 10 | 13 | 76.9 | 63.1 | 0 | 4 | 4 | 3 | +12 | ||
| 11 | | D. Wade | 39 | 2/26/2013 | vs | 45 | 8 | 7 | 3 | 2 | 19 | 28 | 67.9 | 1 | 2 | 50.0 | 0 | 2 | 0.0 | 67.5 | 2 | 6 | 4 | 1 | +5 | ||
| 12 | | D. Wade | 39 | 3/25/2011 | vs | 41 | 11 | 8 | 3 | 5 | 15 | 26 | 57.7 | 1 | 3 | 33.3 | 8 | 11 | 72.7 | 63.2 | 4 | 7 | 2 | 3 | +24 | ||
| 13 | | D. Wade | 39 | 11/9/2010 | vs | 42 | 6 | 1 | 1 | 0 | 12 | 23 | 52.2 | 3 | 5 | 60.0 | 12 | 16 | 75.0 | 64.9 | 1 | 5 | 2 | 3 | -1 | ||
| 14 | | D. Wade | 39 | 4/3/2010 | @ | 40 | 8 | 6 | 0 | 0 | 15 | 27 | 55.6 | 1 | 2 | 50.0 | 8 | 10 | 80.0 | 62.1 | 1 | 7 | 5 | 3 | +20 | ||
| 15 | | D. Wade | 38 | 5/1/2011 | vs | 37 | 1 | 5 | 3 | 2 | 14 | 21 | 66.7 | 2 | 5 | 40.0 | 8 | 9 | 88.9 | 76.1 | 0 | 1 | 2 | 4 | +8 | ||
| 16 | | D. Wade | 38 | 3/8/2011 | vs | 43 | 6 | 5 | 1 | 2 | 12 | 21 | 57.1 | 2 | 8 | 25.0 | 12 | 13 | 92.3 | 71.1 | 1 | 5 | 3 | 4 | -12 | ||
| 17 | | D. Wade | 38 | 3/14/2010 | vs | 36 | 5 | 2 | 5 | 1 | 14 | 25 | 56.0 | 1 | 4 | 25.0 | 9 | 11 | 81.8 | 63.7 | 1 | 4 | 1 | 1 | +13 | ||
| 18 | | D. Wade | 38 | 3/6/2010 | vs | 42 | 4 | 10 | 2 | 0 | 10 | 25 | 40.0 | 4 | 9 | 44.4 | 14 | 18 | 77.8 | 57.7 | 1 | 3 | 1 | 3 | +13 | ||
| 19 | | D. Wade | 37 | 1/15/2010 | @ | 42 | 3 | 8 | 3 | 1 | 15 | 24 | 62.5 | 0 | 1 | 0.0 | 7 | 7 | 100.0 | 68.3 | 2 | 1 | 2 | 2 | +12 | ||
| 20 | | D. Wade | 36 | 3/14/2012 | @ | 39 | 7 | 1 | 1 | 2 | 16 | 26 | 61.5 | 1 | 3 | 33.3 | 3 | 4 | 75.0 | 64.8 | 1 | 6 | 3 | 1 | -13 | ||
| 21 | | D. Wade | 36 | 6/2/2011 | vs | 42 | 5 | 6 | 3 | 1 | 13 | 20 | 65.0 | 2 | 7 | 28.6 | 8 | 12 | 66.7 | 71.2 | 2 | 3 | 1 | 2 | +5 | ||
| 22 | | D. Wade | 36 | 12/11/2010 | @ | 36 | 6 | 6 | 1 | 1 | 15 | 23 | 65.2 | 1 | 2 | 50.0 | 5 | 9 | 55.6 | 66.8 | 3 | 3 | 3 | 2 | +31 | ||
| 23 | | D. Wade | 36 | 3/18/2010 | vs | 45 | 10 | 7 | 1 | 1 | 12 | 26 | 46.2 | 3 | 7 | 42.9 | 9 | 10 | 90.0 | 59.2 | 3 | 7 | 1 | 4 | -10 | ||
| 24 | | D. Wade | 36 | 11/12/2009 | vs | 38 | 4 | 5 | 0 | 2 | 9 | 21 | 42.9 | 3 | 6 | 50.0 | 15 | 21 | 71.4 | 59.5 | 0 | 4 | 4 | 1 | -4 | ||
| 25 | | D. Wade | 35 | 1/23/2013 | vs | 40 | 5 | 7 | 0 | 1 | 13 | 19 | 68.4 | 0 | 1 | 0.0 | 9 | 15 | 60.0 | 68.4 | 2 | 3 | 3 | 4 | +10 | ||
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| Eastern | W | L | PCT | GB | |
|---|---|---|---|---|---|
| 1 |  Pistons - z | 60 | 22 | .732 | |
| 2 |  Celtics - x | 56 | 26 | .683 | 4.0 |
| 3 |  Knicks - x | 53 | 29 | .646 | 7.0 |
| 4 |  Cavaliers - x | 52 | 30 | .634 | 8.0 |
| 5 |  Raptors - x | 46 | 36 | .561 | 14.0 |
| 6 |  Hawks - x | 46 | 36 | .561 | 14.0 |
| 7 |  76ers - x | 45 | 37 | .549 | 15.0 |
| 8 |  Magic - x | 45 | 37 | .549 | 15.0 |
| 9 | 44 | 38 | .537 | 16.0 | |
| 10 | 43 | 39 | .524 | 17.0 | |
| 11 |  Bucks - e | 32 | 50 | .390 | 28.0 |
| 12 |  Bulls - e | 31 | 51 | .378 | 29.0 |
| 13 |  Nets - e | 20 | 62 | .244 | 40.0 |
| 14 |  Pacers - e | 19 | 63 | .232 | 41.0 |
| 15 |  Wizards - e | 17 | 65 | .207 | 43.0 |
| Western | W | L | PCT | GB | |
|---|---|---|---|---|---|
| 1 |  Thunder - z | 64 | 18 | .780 | |
| 2 |  Spurs - x | 62 | 20 | .756 | 2.0 |
| 3 |  Nuggets - x | 54 | 28 | .659 | 10.0 |
| 4 |  Lakers - x | 53 | 29 | .646 | 11.0 |
| 5 |  Rockets - x | 52 | 30 | .634 | 12.0 |
| 6 |  Timberwolves - x | 49 | 33 | .598 | 15.0 |
| 7 |  Suns - x | 45 | 37 | .549 | 19.0 |
| 8 |  Trail Blazers - x | 42 | 40 | .512 | 22.0 |
| 9 | 42 | 40 | .512 | 22.0 | |
| 10 | 37 | 45 | .451 | 27.0 | |
| 11 |  Pelicans - e | 26 | 56 | .317 | 38.0 |
| 12 |  Mavericks - e | 26 | 56 | .317 | 38.0 |
| 13 |  Grizzlies - e | 25 | 57 | .305 | 39.0 |
| 14 |  Kings - e | 22 | 60 | .268 | 42.0 |
| 15 |  Jazz - e | 22 | 60 | .268 | 42.0 |
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