The Buffalo Bills have a 16-12 record in the regular-season and playoffs at home versus the Broncos all-time.
| OPP | REC | W% | GP | W | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 16-12 | .571 | 28 | 16 | 12 | 0 | 73 | 636 | 22.7 | 531 | 19.0 | 518 | |||
| 2 | 7-11-1 | .395 | 19 | 7 | 11 | 1 | 35 | 332 | 17.5 | 388 | 20.4 | 327 | |||
| 3 | 39-26 | .600 | 65 | 39 | 26 | 0 | 176 | 1,518 | 23.4 | 1,240 | 19.1 | 1,263 | |||
| 4 | 16-7 | .696 | 23 | 16 | 7 | 0 | 80 | 623 | 27.1 | 472 | 20.5 | 460 | |||
| 5 | 13-14 | .481 | 27 | 13 | 14 | 0 | 63 | 569 | 21.1 | 537 | 19.9 | 476 | |||
| 6 | 16-10-1 | .611 | 27 | 16 | 10 | 1 | 80 | 651 | 24.1 | 546 | 20.2 | 516 | |||
| 7 | 27-39-1 | .410 | 67 | 27 | 39 | 1 | 152 | 1,260 | 18.8 | 1,478 | 22.1 | 1,186 | |||
| 8 | 37-26 | .587 | 63 | 37 | 26 | 0 | 175 | 1,458 | 23.1 | 1,222 | 19.4 | 1,191 | |||
| 9 | 11-6 | .647 | 17 | 11 | 6 | 0 | 47 | 403 | 23.7 | 344 | 20.2 | 317 | |||
| 10 | 5-3 | .625 | 8 | 5 | 3 | 0 | 22 | 190 | 23.8 | 151 | 18.9 | 146 | |||
| 11 | 24-14 | .632 | 38 | 24 | 14 | 0 | 95 | 808 | 21.3 | 688 | 18.1 | 713 | |||
| 12 | 4-3 | .571 | 7 | 4 | 3 | 0 | 18 | 145 | 20.7 | 130 | 18.6 | 129 | |||
| 13 | 5-1 | .833 | 6 | 5 | 1 | 0 | 24 | 190 | 31.7 | 112 | 18.7 | 99 | |||
| 14 | 4-2 | .667 | 6 | 4 | 2 | 0 | 17 | 146 | 24.3 | 100 | 16.7 | 121 | 25.0 | ||
| 15 | 10-7 | .588 | 17 | 10 | 7 | 0 | 49 | 409 | 24.1 | 347 | 20.4 | 360 | |||
| 16 | 4-1-1 | .750 | 6 | 4 | 1 | 1 | 14 | 109 | 18.2 | 93 | 15.5 | 102 | 40.0 | ||
| 17 | 4-5 | .444 | 9 | 4 | 5 | 0 | 22 | 183 | 20.3 | 187 | 20.8 | 163 | |||
| 18 | 4-3 | .571 | 7 | 4 | 3 | 0 | 16 | 132 | 18.9 | 126 | 18.0 | 129 | 55.6 | ||
| 19 | 4-4 | .500 | 8 | 4 | 4 | 0 | 18 | 140 | 17.5 | 141 | 17.6 | 149 | |||
| 20 | 4-5 | .444 | 9 | 4 | 5 | 0 | 18 | 163 | 18.1 | 210 | 23.3 | 196 | |||
| 21 | 4-3 | .571 | 7 | 4 | 3 | 0 | 18 | 157 | 22.4 | 134 | 19.1 | 146 | 80.0 | ||
| 22 | 6-5 | .545 | 11 | 6 | 5 | 0 | 24 | 235 | 21.4 | 168 | 15.3 | 210 | |||
| 23 | 7-3 | .700 | 10 | 7 | 3 | 0 | 28 | 228 | 22.8 | 148 | 14.8 | 218 | |||
| 24 | 7-0 | 1.000 | 7 | 7 | 0 | 0 | 18 | 175 | 25.0 | 90 | 12.9 | 129 | |||
| 25 | 2-4 | .333 | 6 | 2 | 4 | 0 | 12 | 100 | 16.7 | 160 | 26.7 | 93 | |||
Bears
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More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |