The Buffalo Bills put up their most points in a game against the Dolphins on September 18, 1966, with 58 points.
Interpreted as:
buffalo bills most points in a regular-season game| TEAM | PTS | DATE | TM | OPP | RESULT | PASS TD | RUSH TD | RET TD | TD | FGM | XPM | XP2 | SFTY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 58 | 9/18/1966 | vs | W 58-24 | 2 | 4 | 2 | 8 | 1 | 7 | 0 | 0 | ||
| 2 | | Bills | 56 | 1/3/2021 | vs | W 56-26 | 4 | 2 | 2 | 8 | 0 | 8 | 0 | 0 | ||
| 3 | | Bills | 54 | 11/23/2008 | @ | W 54-31 | 2 | 3 | 1 | 6 | 4 | 6 | 0 | 0 | ||
| 4 | | Bills | 52 | 9/8/1991 | vs | W 52-34 | 6 | 0 | 1 | 7 | 1 | 7 | 0 | |||
| 5 | | Bills | 51 | 9/9/1979 | vs | W 51-24 | 0 | 5 | 2 | 7 | 1 | 6 | 0 | |||
| 6 | | Bills | 50 | 10/3/1976 | vs | W 50-17 | 3 | 3 | 1 | 7 | 1 | 5 | 0 | |||
| 7 | | Bills | 49 | 11/21/2010 | @ | W 49-31 | 4 | 2 | 1 | 7 | 0 | 7 | 0 | 0 | ||
| 8 | | Bills | 48 | 12/15/2024 | @ | W 48-42 | 2 | 4 | 0 | 6 | 2 | 6 | 0 | 0 | ||
| 9 | | Bills | 48 | 10/1/2023 | vs | W 48-20 | 4 | 2 | 0 | 6 | 2 | 6 | 0 | 0 | ||
| 10 | | Bills | 48 | 12/19/2020 | @ | W 48-19 | 2 | 3 | 1 | 6 | 2 | 6 | 0 | 0 | ||
| 11 | | Bills | 48 | 10/11/1964 | @ | W 48-17 | 3 | 3 | 0 | 6 | 2 | 6 | 0 | 0 | ||
| 12 | | Bills | 47 | 9/23/2024 | vs | W 47-10 | 4 | 2 | 0 | 6 | 2 | 5 | 0 | 0 | ||
| 13 | | Bills | 47 | 12/19/1993 | @ | W 47-34 | 1 | 3 | 2 | 6 | 2 | 5 | 0 | |||
| 14 | | Bills | 47 | 9/24/1989 | @ | W 47-41 | 5 | 0 | 1 | 6 | 2 | 5 | 0 | |||
| 15 | | Bills | 46 | 9/23/1979 | vs | W 46-31 | 5 | 0 | 1 | 6 | 2 | 4 | 0 | |||
| 16 | | Bills | 45 | 11/14/2021 | @ | W 45-17 | 2 | 4 | 0 | 6 | 1 | 6 | 0 | 0 | ||
| 17 | | Bills | 45 | 10/16/2016 | vs | W 45-16 | 2 | 4 | 0 | 6 | 1 | 6 | 0 | 0 | ||
| 18 | | Bills | 45 | 9/15/2002 | @ | W 45-39 | 3 | 0 | 2 | 5 | 4 | 3 | 0 | 0 | ||
| 19 | | Bills | 45 | 12/27/1998 | @ | W 45-33 | 3 | 3 | 0 | 6 | 1 | 6 | 0 | 0 | ||
| 20 | | Bills | 45 | 12/10/1995 | @ | W 45-27 | 4 | 2 | 0 | 6 | 1 | 6 | 0 | 0 | ||
| 21 | | Bills | 45 | 11/11/1990 | vs | W 45-14 | 4 | 2 | 0 | 6 | 1 | 6 | 0 | |||
| 22 | | Bills | 45 | 11/23/1975 | vs | W 45-31 | 4 | 2 | 0 | 6 | 1 | 6 | 0 | |||
| 23 | | Bills | 45 | 11/1/1970 | @ | W 45-10 | 2 | 2 | 2 | 6 | 1 | 6 | 0 | |||
| 24 | | Bills | 45 | 12/8/1963 | vs | W 45-14 | 1 | 5 | 0 | 6 | 1 | 6 | 0 | 0 | ||
| 25 | | Bills | 45 | 10/28/1962 | @ | W 45-38 | 2 | 3 | 1 | 6 | 1 | 4 | 1 | 0 | ||
PIT
HOU
NYJ
STL
PHXMore Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,606
Cook
REC
719
Shakir
Team Rankings
PPG
27.9
6th
OPP PPG
22.3
13th
RUSH YDS/G
156.4
2nd
PASS YDS/G
232.6
17th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 13 | 3 | 0 | .813 |
 Bills - x | 11 | 5 | 0 | .688 |
 Dolphins - e | 7 | 9 | 0 | .438 |
 Jets - e | 3 | 13 | 0 | .188 |
| AFC North | W | L | T | PCT |
9 | 7 | 0 | .563 | |
8 | 8 | 0 | .500 | |
 Bengals - e | 6 | 10 | 0 | .375 |
 Browns - e | 4 | 12 | 0 | .250 |
| AFC South | W | L | T | PCT |
 Jaguars - x | 12 | 4 | 0 | .750 |
 Texans - x | 11 | 5 | 0 | .688 |
 Colts - e | 8 | 8 | 0 | .500 |
 Titans - e | 3 | 13 | 0 | .188 |
| AFC West | W | L | T | PCT |
 Broncos - y | 13 | 3 | 0 | .813 |
 Chargers - w | 11 | 5 | 0 | .688 |
 Chiefs - e | 6 | 10 | 0 | .375 |
 Raiders - e | 2 | 14 | 0 | .125 |
Ravens| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 5 | 0 | .688 |
 Cowboys - e | 7 | 8 | 1 | .469 |
 Commanders - e | 4 | 12 | 0 | .250 |
 Giants - e | 3 | 13 | 0 | .188 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 4 | 0 | .733 |
 Packers - w | 9 | 6 | 1 | .594 |
 Vikings - e | 8 | 8 | 0 | .500 |
 Lions - e | 8 | 8 | 0 | .500 |
| NFC South | W | L | T | PCT |
8 | 8 | 0 | .500 | |
7 | 9 | 0 | .438 | |
 Falcons - e | 6 | 9 | 0 | .400 |
 Saints - e | 6 | 10 | 0 | .375 |
| NFC West | W | L | T | PCT |
 Seahawks - x | 13 | 3 | 0 | .813 |
 49ers - x | 11 | 4 | 0 | .733 |
 Rams - x | 11 | 4 | 0 | .733 |
 Cardinals - e | 3 | 13 | 0 | .188 |
Panthers
Buccaneers
