The San Francisco 49ers had their most assists in a game versus the Cardinals on November 16, with 54 assists.

Interpreted as:

highest sf career assist in a regular-season game average

	TEAM	AST	DATE	TM		OPP	RESULT	TKL	COMB	SCK	SCKY	INT	INT YDS	INT TD	FF	FR	FR TD
1	49ers	54	11/16/2025	SF	@	ARI	W 41-22	41	95	0.0	0	2	64	0	1	1	0
2	49ers	45	10/26/2025	SF	@	HOU	L 15-26	46	91	0.0	0	1	26	0	0	0	0
3	49ers	44	9/25/2016	SF	@	SEA	L 18-37	33	77	2.0	17	1	4	0	1	1	0
4	49ers	44	12/23/2012	SF	@	SEA	L 13-42	26	70	1.0	1	1	2	0	0	0	0
5	49ers	44	10/5/2008	SF	vs	NE	L 21-30	48	92	5.0	26	2	13	0	0	0	0
6	49ers	43	9/21/2025	SF	vs	ARI	W 16-15	34	77	1.0	5	0	0	0	1	0	0
7	49ers	42	11/9/2025	SF	vs	LAR	L 26-42	33	75	1.0	5	0	0	0	0	0	0
8	49ers	42	11/7/2021	SF	vs	ARI	L 17-31	46	88	2.0	8	0	0	0	1	0	0
9	49ers	40	12/12/2024	SF	vs	LAR	L 6-12	38	78	0.0	0	0	0	0	0	0	0
10	49ers	40	11/22/2015	SF	@	SEA	L 13-29	45	85	2.0	7	0	0	0	0	0	0
11	49ers	40	10/7/2007	SF	vs	BAL	L 7-9	45	85	0.0	0	0	0	0	0	0	0
12	49ers	39	12/12/2021	SF	@	CIN	W 26-23	42	81	5.0	37	0	0	0	1	2	0
13	49ers	38	9/25/2022	SF	@	DEN	L 10-11	43	81	4.0	24	0	0	0	2	0	0
14	49ers	38	9/18/2016	SF	@	CAR	L 27-46	47	85	1.0	0	1	0	0	2	3	0
15	49ers	38	9/15/2013	SF	@	SEA	L 3-29	43	81	4.0	24	1	1	0	0	0	0
16	49ers	37	12/24/2022	SF	vs	WAS	W 37-20	52	89	2.0	19	1	0	0	1	1	0
17	49ers	36	12/22/2025	SF	@	IND	W 48-27	31	67	2.0	23	1	74	1	2	1	0
18	49ers	36	12/23/2007	SF	vs	TB	W 21-19	49	85	4.0	14	1	62	0	2	1	0
19	49ers	35	11/2/2025	SF	@	NYG	W 34-24	35	70	2.0	12	0	0	0	0	0	0
20	49ers	35	1/1/2023	SF	@	LV	W 37-34	35	70	0.0	0	2	56	0	0	0	0
21	49ers	35	1/2/2022	SF	vs	HOU	W 23-7	41	76	3.0	27	1	2	0	2	0	0
22	49ers	35	12/26/2004	SF	vs	BUF	L 7-41	49	84	1.0	1	0	0	0	1	1	0
23	49ers	34	12/14/2025	SF	vs	TEN	W 37-24	23	57	0.0	0	0	0	0	0	0	0
24	49ers	33	10/3/2021	SF	vs	SEA	L 21-28	29	62	3.0	20	0	0	0	2	0	0
25	49ers	33	11/11/2019	SF	vs	SEA	L 24-27	51	84	5.0	43	1	47	0	5	3	1

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StatMuse has team, game-level data for assists going back to the 2001 season.

More 49ers Stats

Team Leaders

PASS

2,167

Purdy

RUSH

1,202

McCaffrey

REC

924

McCaffrey

Team Rankings

PPG

25.7

10th

OPP PPG

21.8

13th

RUSH YDS/G

106.9

24th

PASS YDS/G

254.0

6th

2025 Division Standings

TEAM	W	L	PCT
Seahawks	14	3	.824
Rams	12	5	.706
49ers	12	5	.706
Cardinals	3	14	.176

Schedule

DATE	MATCHUP			TIME (ET)
Sun 1/11	SF	@	PHI	4:30 PM

Last Game

Seahawks

14 - 3

Final

49ers

12 - 5

Sat 3 Jan 2026

NFL 2025 Leaders

Playoffs Pass Yards Leaders

361

Williams

323

Love

304

Stafford

Playoffs Rush Yards Leaders

57

Williams

55

Jacobs

54

Swift

Playoffs Rec Yards Leaders

137

Loveland

134

Coker

124

Doubs

Playoffs Pass TD Leaders

4

Love

3

Stafford

2

Williams

Playoffs Rush TD Leaders

2

Hubbard

1

Nacua

1

Young

Playoffs Rec TD Leaders

1

Golden

1

Nacua

1

Reed

Playoffs QB Rating Leaders

103.8

Love

93.8

Stafford

71.6

Williams

Playoffs Sack Leaders

1.0

Booker

1.0

Fiske

1.0

Van Ness

NFL 2025 Rankings

Playoffs PPG Rankings

34.0

31.0

27.0

Playoffs Opp PPG Rankings

27.0

31.0

34.0

Playoffs Total Yards Rankings

445.0

421.0

411.0

333.0

Playoffs Rush Yards Rankings

116.0

99.0

93.0

83.0

Playoffs Pass Yards Rankings

361.0

323.0

304.0

264.0

Playoffs Sack Leaders

2.0

1.0

NFL Fantasy 2025

Playoffs Fantasy RB Rankings

17.9

Hubbard

15.2

Swift

13.5

Williams

Playoffs Fantasy WR Rankings

24.5

Nacua

19.4

Coker

18.4

Doubs

Playoffs Fantasy TE Rankings

15.7

Loveland

9.4

Parkinson

4.5

Higbee

Playoffs Fantasy K Rankings

13

Santos

12

Mevis

8

Fitzgerald

NFL 2025 Betting

Best Record ATS

12-5

12-6

11-6

11-6-1

Worst Record ATS

5-12

5-12-1

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176

NFL 2025 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Sat 10/4	DET	@	CIN	37-24
Sat 10/4	WAS	@	LAC	27-10
Sat 10/4	NE	@	BUF	23-20
Sun 10/5	KC	@	JAX	28-31
Wed 10/8	PHI	@	NYG	17-34

Schedule

DATE	MATCHUP			TIME (ET)
Sun 1/11	BUF	@	JAX	1:00 PM
Sun 1/11	SF	@	PHI	4:30 PM
Sun 1/11	LAC	@	NE	8:15 PM
Mon 1/12	HOU	@	PIT	8:15 PM

The San Francisco 49ers had their most assists in a game versus the Cardinals on November 16, with 54 assists.

Interpreted as:

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2,167

1,202

924

NFL 2025 Leaders

361

323

304

57

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137

134

124

4

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2

2

1

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1

1

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103.8

93.8

71.6

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NFL 2025 Rankings

NFL Fantasy 2025

17.9

15.2

13.5

24.5

19.4

18.4

15.7

9.4

4.5

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8

NFL 2025 Betting

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NFL 2025 Scores & Schedule

Scores

Schedule