The San Francisco 49ers are 8-12 against the spread in their last 20 games against the Seahawks at home.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/30/2007 | 0-1 | +110 | vs | -130 | L 3-23 | +2 | -18 (N) | 40.5 | -14.5 (U) | 0 | 9 | 184 | 371 | 14.3 | 0.0 | ||
| 2 | | 49ers | 10/26/2008 | 0-1 | -245 | vs | +200 | L 13-34 | -5 | -26 (N) | 41 | +6 (O) | 1 | 21 | 388 | 261 | 46.7 | 0.0 | ||
| 3 | | 49ers | 9/20/2009 | 1-0 | -120 | vs | +100 | W 23-10 | -1 | +12 (Y) | 39.5 | -6.5 (U) | 2 | 16 | 379 | 283 | 33.3 | |||
| 4 | | 49ers | 12/12/2010 | 1-0 | -220 | vs | +180 | W 40-21 | -5 | +14 (Y) | 41.5 | +19.5 (O) | 4 | 10 | 336 | 361 | 41.2 | |||
| 5 | | 49ers | 9/11/2011 | 1-0 | -250 | vs | +210 | W 33-17 | -6 | +10 (Y) | 37.5 | +12.5 (O) | 3 | 12 | 209 | 219 | 8.3 | |||
| 6 | | 49ers | 10/18/2012 | 0-1 | -380 | vs | +310 | W 13-6 | -9 | -2 (N) | 37.5 | -18.5 (U) | 1 | 18 | 313 | 251 | 27.3 | |||
| 7 | | 49ers | 12/8/2013 | 0-1 | -135 | vs | +115 | W 19-17 | -2.5 | -0.5 (N) | 41 | -5 (U) | 1 | 19 | 318 | 264 | 38.5 | |||
| 8 | | 49ers | 11/27/2014 | 0-1 | -130 | vs | +110 | L 3-19 | -1 | -17 (N) | 40 | -18 (U) | 0 | 16 | 164 | 379 | 36.4 | |||
| 9 | | 49ers | 10/22/2015 | 0-1 | +225 | vs | -300 | L 3-20 | +6 | -11 (N) | 42 | -19 (U) | 0 | 8 | 142 | 388 | 9.1 | |||
| 10 | | 49ers | 1/1/2017 | 1-0 | +450 | vs | -600 | L 23-25 | +11.5 | +9.5 (Y) | 43.5 | +4.5 (O) | 3 | 14 | 253 | 376 | 18.2 | 66.7 | ||
| 11 | | 49ers | 11/26/2017 | 0-1 | +260 | vs | -290 | L 13-24 | +6.5 | -4.5 (N) | 44.5 | -7.5 (U) | 1 | 16 | 280 | 318 | 31.3 | 100.0 | ||
| 12 | | 49ers | 12/16/2018 | 1-0 | +185 | vs | -200 | W 26-23 | +4 | +7 (Y) | 44 | +5 (O) | 2 | 20 | 351 | 385 | 30.0 | |||
| 13 | | 49ers | 11/11/2019 | 0-1 | -272 | vs | +221 | L 24-27 | -6.5 | -9.5 (N) | 47 | +4 (O) | 2 | 21 | 302 | 336 | 40.0 | 0.0 | ||
| 14 | | 49ers | 1/3/2021 | 1-0 | +270 | vs | -338 | L 23-26 | +7 | +4 (Y) | 45.5 | +3.5 (O) | 2 | 17 | 328 | 280 | 40.0 | 100.0 | ||
| 15 | | 49ers | 10/3/2021 | 0-1 | -137 | vs | +115 | L 21-28 | -2.5 | -9.5 (N) | 52 | -3 (U) | 3 | 23 | 457 | 234 | 14.3 | 75.0 | ||
| 16 | | 49ers | 9/18/2022 | 1-0 | -394 | vs | +306 | W 27-7 | -8.5 | +11.5 (Y) | 39.5 | -5.5 (U) | 3 | 25 | 373 | 216 | 40.0 | 66.7 | ||
| 17 | | 49ers | 1/14/2023 | 1-0 | -480 | vs | +366 | W 41-23 | -9.5 | +8.5 (Y) | 42 | +22 (O) | 4 | 24 | 505 | 332 | 54.5 | |||
| 18 | | 49ers | 12/10/2023 | 0-1 | -1099 | vs | +683 | W 28-16 | -14.5 | -2.5 (N) | 44.5 | -0.5 (U) | 4 | 19 | 527 | 324 | 54.5 | |||
| 19 | | 49ers | 11/17/2024 | 0-1 | -262 | vs | +214 | L 17-20 | -6 | -9 (N) | 48.5 | -11.5 (U) | 2 | 21 | 277 | 289 | 63.6 | |||
| 20 | | 49ers | 1/3/2026 | 0-1 | +131 | vs | -156 | L 3-13 | +2.5 | -7.5 (N) | 48.5 | -32.5 (U) | 0 | 9 | 173 | 361 | 22.2 | 0.0 | ||
| Average | 2.0 | 1.9 | 16.9 | 313.0 | 311.4 | 33.5 | 0.1 | |||||||||||||
| Total | 8-12 | 38 | 338 | 6,259 | 6,228 | 33.5 | 50.0 |
StatMuse has team, game-level data for spread records going back to the 1979 season.
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More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |