Since 1999-00, Lionel Messi has tallied the most goals in Europe's top five leagues, with 496 goals in LaLiga and Ligue 1.

most goals by a player scored from 2000s

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Lionel Messi L. Messi	496	578	47,162	520	0.86	136	632	60
2	Cristiano Ronaldo C. Ronaldo	495	626	51,094	566	0.79	96	591	98
3	Robert Lewandowski R. Lewandowski	385	494	39,716	447	0.78	73	458	47
4	Zlatan Ibrahimovic Z. Ibrahimovic	302	467	36,675	417	0.65	70	372	58
5	Harry Kane H. Kane	287	391	32,861	370	0.73	67	354	51
6	Karim Benzema K. Benzema	281	551	39,192	456	0.51	88	369	28
7	Edinson Cavani E. Cavani	267	479	35,355	394	0.56	41	308	40
8	Sergio Agüero S. Agüero	258	454	33,350	386	0.57	47	305	28
9	Luis Suárez L. Suárez	247	368	29,863	336	0.67	96	343	14
10	Pierre-Emerick Aubameyang P. Aubameyang	239	467	35,473	395	0.51	64	303	24
11	Gonzalo Higuaín G. Higuaín	237	428	30,147	338	0.55	29	266	15
12	Kylian Mbappé K. Mbappé	233	290	22,015	246	0.80	72	305	29	1	1,084	560	27	13,552	2,450	268
13	Mohamed Salah M. Salah	224	391	31,601	357	0.57	108	332	35
14	Edin Džeko E. Džeko	223	517	35,657	382	0.43	72	295	5
15	Alexandre Lacazette A. Lacazette	215	455	32,576	373	0.47	53	268	41
16	Francesco Totti F. Totti	214	472	36,699	424	0.45	46	260	67
17	Thierry Henry T. Henry	210	338	26,999	301	0.62	74	284	23
18	Antonio Di Natale A. Di Natale	209	445	33,917	389	0.47	27	236	33
19	Samuel Eto'o S. Eto'o	209	399	31,958	363	0.52	14	223	25
20	Wayne Rooney W. Rooney	208	491	38,027	421	0.42	100	308	23
21	Ciro Immobile C. Immobile	206	386	28,240	323	0.53	50	256	52
22	Romelu Lukaku R. Lukaku	205	443	33,719	374	0.46	65	270	24
23	Antoine Griezmann A. Griezmann	199	540	40,858	475	0.37	75	274	12
24	Wissam Ben Yedder W. Ben Yedder	199	411	29,510	341	0.48	56	255	36
25	Claudio Pizarro C. Pizarro	199	511	31,375	325	0.39	34	233	10