most wins by a starting pitcher vs one team

Grover Alexander has won the most career games by a starting pitcher against a team, with 67 wins against the Reds.

Interpreted as:

most regular-season wins by a starting pitcher vs one team

	NAME	W	OPP	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Grover Alexander G. Alexander	67	Reds	21	.761	96	96	2.01	288	74	20	0	806.2	698		227	10	139	12	0		3,164	5	3.21	1.55	2.07	0.11	9.1	4.4	1.04	.253	2.53	7.79
2	Warren Spahn W. Spahn	63	Cardinals	41	.606	115	115	2.98	367	66	11	0	900.0	828	298	339	62	243	8	0	9	3,711	20	3.67	2.43	1.51	0.62	9.9	6.5	1.19	.253	3.39	8.28
3	Warren Spahn W. Spahn	60	Reds	25	.706	95	95	2.85	355	59	9	0	745.0	686	236	265	63	193	8	0	11	3,056	10	4.29	2.33	1.84	0.76	11.6	6.3	1.18	.256	3.20	8.29
4	Christy Mathewson C. Mathewson	60	Reds	19	.759	83	83	0.87	345	69	12	0	692.1	611		225	13	118	12	0			11	4.48	1.53	2.92	0.17		4.3	1.05	.265	2.92	7.94
5	Walter Johnson W. Johnson	59	Tigers	37	.615	105	105	1.94	479	79	12	0	863.2	749		320	11	263	28	0			23	4.99	2.74	1.82	0.11		7.5	1.17	.273	3.33	7.81
6	Walter Johnson W. Johnson	57	Yankees	34	.626	94	94	1.57	489	78	21	0	795.2	644		242	20	200	29	0		3,179	28	5.53	2.26	2.44	0.23	15.4	6.3	1.06	.256	2.74	7.28
7	Warren Spahn W. Spahn	56	Giants	40	.583	108	108	3.20	404	67	6	0	839.2	768	299	321	96	233	8	0	5	3,441	11	4.33	2.50	1.73	1.03	11.7	6.8	1.19	.249	3.44	8.23
8	Walter Johnson W. Johnson	56	Athletics	34	.622	93	93	1.77	479	74	23	0	776.1	671		261	22	172	24	0		3,152	18	5.55	1.99	2.78	0.26	15.2	5.5	1.09	.264	3.03	7.78
9	Walter Johnson W. Johnson	55	White Sox	33	.625	99	99	1.40	499	81	14	0	834.2	613		231	10	183	25	0		3,257	23	5.38	1.97	2.73	0.11	15.3	5.6	0.95	.237	2.49	6.61
10	Eddie Plank E. Plank	55	Tigers	31	.640	92	92	1.48	355	75	11	0	743.1	720		272	7	168	22	0			13	4.30	2.03	2.11	0.08		5.7	1.19	.299	3.29	8.72
11	Lefty Grove L. Grove	53	Tigers	18	.746	79	79	3.02	347	59	7	0	643.0	591	216	248	34	177	7	0		2,665	7	4.86	2.48	1.96	0.48	13.0	6.6	1.19	.265	3.47	8.27
12	Grover Alexander G. Alexander	53	Braves	24	.688	83	83	2.06	293	66	11	0	712.1	652		224	20	103	8	0		2,861	5	3.70	1.30	2.84	0.25	10.2	3.6	1.06	.259	2.83	8.24
13	Christy Mathewson C. Mathewson	52	Braves	22	.703	78	78	1.17	397	63	14	0	660.1	578		200	9	127	7	0		2,638	16	5.41	1.73	3.13	0.12	15.0	4.8	1.07	.271	2.73	7.88
14	Grover Alexander G. Alexander	51	Robins	23	.689	81	81	1.96	294	63	16	0	698.0	631		221	13	116	6	0		2,806	8	3.79	1.50	2.53	0.17	10.5	4.1	1.07	.260	2.85	8.14
15	Walter Johnson W. Johnson	51	Indians	39	.567	93	93	1.91	433	71	12	0	763.0	686		261	9	143	29	0		3,077	22	5.11	1.69	3.03	0.11	14.1	4.6	1.09	.275	3.08	8.09
16	Walter Johnson W. Johnson	50	Browns	32	.610	91	91	1.63	431	73	13	0	743.2	612		236	12	165	28	0		2,962	19	5.22	2.00	2.61	0.15	14.6	5.6	1.04	.258	2.86	7.41
17	Christy Mathewson C. Mathewson	49	Phillies	23	.681	77	77	0.80	330	57	9	0	620.2	566		207	12	126	10	0			16	4.79	1.83	2.62	0.17		5.1	1.11	.281	3.00	8.21
18	Warren Spahn W. Spahn	48	Pirates	32	.600	95	95	3.34	378	49	9	0	707.0	671	262	296	50	215	4	0	15	2,945	9	4.81	2.74	1.76	0.64	12.8	7.3	1.25	.270	3.77	8.54
19	Early Wynn E. Wynn	48	Athletics	24	.667	86	86	3.19	294	44	5	0	630.0	576	223	246	40	222	9	0	2	2,632	3	4.20	3.17	1.32	0.57	11.2	8.4	1.27	.259	3.51	8.23
20	Red Faber R. Faber	48	Tigers	24	.667	83	83	3.09	213	51	8	0	608.1	614	209	268	14	194	14	0		2,592	7	3.15	2.87	1.10	0.21	8.2	7.5	1.33	.278	3.96	9.08
21	Walter Johnson W. Johnson	48	Red Sox	40	.545	91	91	1.61	463	75	15	0	775.0	635		215	6	169	28	0		3,077	11	5.38	1.96	2.74	0.07	15.0	5.5	1.04	.261	2.50	7.37
22	Christy Mathewson C. Mathewson	48	Cardinals	20	.706	72	72	1.14	282	53	9	0	582.1	528		190	11	110	5	0		2,319	15	4.36	1.70	2.56	0.17	12.2	4.7	1.10	.271	2.94	8.16
23	Warren Spahn W. Spahn	47	Phillies	27	.635	83	83	2.76	332	49	11	0	652.2	569	200	227	43	176	5	0	5	2,646	7	4.58	2.43	1.89	0.59	12.5	6.7	1.14	.252	3.13	7.85
24	Warren Spahn W. Spahn	47	Cubs	16	.746	74	74	2.81	333	44	10	0	566.1	515	177	200	49	117	1	0	2	2,281	5	5.29	1.86	2.85	0.78	14.6	5.1	1.12	.262	3.18	8.18
25	Carl Hubbell C. Hubbell	47	Pirates	21	.691	73	73	3.10	209	48	5	0	557.2	565	192	224	24	116	8	0		2,333	8	3.37	1.87	1.80	0.39	9.0	5.0	1.22	.274	3.62	9.12