Kerry Wood has fanned the most hitters in a game on May 6, with 20 strikeouts against the Astros on May 6, 1998.
| NAME | SO | DATE | TM | OPP | DEC | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | K. Wood | 20 | 5/6/1998 |  CHC | vs |  HOU | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 29 | 0 |
| 2 |  | P. Martinez | 17 | 5/6/2000 |  BOS | vs |  TBD | L | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 6 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 34 | 0 |
| 3 | | C. Lee | 16 | 5/6/2011 |  PHI | vs |  ATL | L | 1 | 3.86 | 0 | 0 | 0 | 7.0 | 9 | 3 | 3 | 0 | 1 | 0 | 0 | 0 | 31 | 0 |
| 4 |  | M. Scherzer | 15 | 5/6/2018 |  WSH | vs | PHI | 1 | 1.42 | 0 | 0 | 0 | 6.1 | 5 | 1 | 1 | 0 | 2 | 1 | 0 | 1 | 26 | 0 | |
| 5 |  | N. Ryan | 15 | 5/6/1977 |  CAL | @ |  BOS | W | 1 | 3.12 | 0 | 0 | 0 | 8.2 | 6 | 3 | 4 | 0 | 7 | 1 | 0 | 0 | 40 | 1 |
| 6 | | S. McDowell | 15 | 5/6/1970 |  CLE | @ |  CWS | L | 1 | 1.08 | 1 | 0 | 0 | 8.1 | 5 | 1 | 2 | 1 | 2 | 0 | 0 | 0 | 30 | 0 |
| 7 |  | S. Koufax | 15 | 5/6/1960 |  LAD | vs | PHI | L | 1 | 4.66 | 0 | 0 | 0 | 9.2 | 9 | 5 | 5 | 2 | 7 | 0 | 0 | 1 | 47 | 1 |
| 8 | | S. McDowell | 14 | 5/6/1968 | CLE | @ |  NYY | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 7 | 2 | 2 | 1 | 3 | 0 | 0 | 0 | 36 | 0 |
| 9 |  | B. Gibson | 14 | 5/6/1966 |  STL | vs |  SFG | L | 1 | 3.00 | 1 | 0 | 0 | 9.0 | 3 | 3 | 4 | 1 | 2 | 0 | 0 | 0 | 33 | 0 |
| 10 | | J. Bunning | 13 | 5/6/1960 |  DET | @ |  BOS | L | 1 | 1.04 | 1 | 0 | 0 | 8.2 | 11 | 1 | 3 | 0 | 2 | 0 | 0 | 1 | 39 | 0 |
| 11 | | B. Turley | 13 | 5/6/1955 | NYY | @ | BOS | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 2 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 36 | 0 |
| 12 |  | C. Sale | 12 | 5/6/2018 | BOS | @ |  TEX | W | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 4 | 1 | 1 | 1 | 1 | 2 | 0 | 0 | 28 | 0 |
| 13 | | J. Peavy | 12 | 5/6/2009 |  SDP | vs |  ARI | L | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 4 | 2 | 2 | 1 | 3 | 0 | 0 | 0 | 28 | 0 |
| 14 | | M. Soto | 12 | 5/6/1983 |  CIN | @ |  NYM | 1 | 3.00 | 0 | 0 | 0 | 9.0 | 4 | 3 | 3 | 2 | 1 | 0 | 0 | 0 | 32 | 0 | |
| 15 | | D. Boswell | 12 | 5/6/1966 |  MIN | vs |  BOS | 1 | 4.50 | 0 | 0 | 0 | 6.0 | 4 | 3 | 3 | 2 | 3 | 0 | 0 | 0 | 25 | 0 | |
| 16 |  | P. López | 11 | 5/6/2025 | MIN | vs |  BAL | W | 1 | 1.80 | 0 | 0 | 0 | 5.0 | 2 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 18 | 0 |
| 17 |  | Z. Wheeler | 11 | 5/6/2024 | PHI | vs | SFG | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 4 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 26 | 1 |
| 18 | | B. Woodruff | 11 | 5/6/2021 |  MIL | @ | PHI | L | 1 | 1.35 | 0 | 0 | 0 | 6.2 | 2 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 24 | 0 |
| 19 | | C. Paddack | 11 | 5/6/2019 |  SDP | vs | NYM | W | 1 | 0.00 | 0 | 0 | 0 | 7.2 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 28 | 0 |
| 20 | | J. Lackey | 11 | 5/6/2016 | CHC | vs | WSH | W | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 6 | 2 | 2 | 1 | 1 | 1 | 0 | 0 | 28 | 0 |
| 21 |  | Y. Darvish | 11 | 5/6/2012 | TEX | @ | CLE | L | 1 | 4.50 | 0 | 0 | 0 | 6.0 | 6 | 3 | 4 | 1 | 4 | 0 | 0 | 0 | 28 | 0 |
| 22 | | M. Latos | 11 | 5/6/2012 | CIN | @ |  PIT | W | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 2 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 25 | 0 |
| 23 | | R. Nolasco | 11 | 5/6/2011 |  FLA | vs | WSH | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 6 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 29 | 0 | |
| 24 | | S. Trachsel | 11 | 5/6/2000 | TBD | @ | BOS | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 34 | 0 |
| 25 | | D. McNally | 11 | 5/6/1970 | BAL | vs |  KCR | W | 1 | 1.08 | 0 | 0 | 0 | 8.1 | 6 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 32 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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