The Philadelphia Phillies have lost the most games by a team, with 11,339 losses.

Interpreted as:

MLB teams with the most regular-season losses all-time

	TEAM	L	W	L%	G	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Phillies	11,339	10,224	.526	21,678	.474	741,746	96,251	193,142	33,386	6,676	14,169	86,477	67,691	5,407	105,209	14,948	2,911	829,768	282,387	54,231	11,914	3,010	3,738	9,853	.260	.326	.381	.706
2	Braves	10,965	11,128	.496	22,247	.504	761,699	99,444	197,836	32,086	6,297	15,040	86,493	67,446	5,060	100,001	14,086	3,062	849,760	287,636	53,423	12,681	2,874	3,651	10,374	.260	.323	.378	.701
3	Pirates	10,838	10,851	.500	21,829	.500	747,747	97,122	196,836	32,335	8,932	12,242	86,632	64,262	5,523	99,457	15,668	3,265	833,326	283,761	53,509	12,557	3,114	3,696	10,041	.263	.325	.379	.704
4	Reds	10,781	10,950	.496	21,870	.504	745,191	98,144	194,169	32,352	7,556	14,305	87,291	66,649	5,501	102,112	18,148	3,401	833,203	284,548	54,213	12,661	3,033	3,645	9,708	.261	.325	.382	.707
5	Cubs	10,780	11,345	.487	22,286	.513	762,664	102,604	199,746	33,727	7,356	15,226	88,193	68,513	5,281	104,923	15,776	3,066	852,386	293,863	56,309	13,026	2,902	3,518	9,953	.262	.326	.385	.711
6	Orioles	10,102	9,132	.525	19,344	.475	657,066	83,536	169,553	29,298	4,909	14,416	77,233	63,243	4,470	98,198	10,540	2,778	738,407	251,917	48,623	10,530	3,098	2,574	10,828	.258	.326	.383	.709
7	Dodgers	10,078	11,453	.468	21,670	.532	738,354	97,811	192,906	31,026	7,003	14,105	88,036	68,840	5,144	100,206	17,332	3,547	828,240	280,253	52,134	12,772	3,054	3,729	9,930	.261	.327	.380	.707
8	Giants	10,031	11,560	.465	21,754	.535	742,458	100,593	195,298	31,325	7,035	15,569	90,068	68,249	5,669	99,445	16,512	3,141	831,047	287,400	53,929	11,662	3,009	4,016	10,168	.263	.329	.387	.716
9	Cardinals	9,987	10,519	.487	20,637	.513	705,927	92,330	187,599	31,801	7,049	12,845	84,397	64,139	5,189	98,028	15,008	3,611	790,360	272,033	51,695	11,971	3,134	3,775	10,125	.266	.330	.385	.715
10	Twins	9,973	9,272	.518	19,354	.482	660,229	85,098	173,151	29,733	6,331	11,996	78,342	62,317	5,152	94,337	12,006	3,075	741,049	251,534	48,060	10,189	3,162	2,661	10,960	.262	.329	.381	.710
11	Athletics	9,874	9,345	.514	19,306	.486	654,374	85,213	168,439	29,168	5,331	14,122	78,518	64,456	4,725	98,887	12,094	3,205	737,334	250,635	48,621	10,681	3,098	2,267	10,604	.257	.327	.383	.710
12	White Sox	9,635	9,601	.501	19,339	.499	654,831	84,012	170,042	28,179	5,550	12,273	77,222	62,044	5,245	91,923	13,609	3,482	737,704	246,140	46,002	12,366	3,218	2,461	10,509	.260	.327	.376	.703
13	Tigers	9,579	9,695	.497	19,367	.503	660,425	88,915	174,480	29,559	6,294	14,554	81,876	65,502	4,437	96,584	11,286	2,935	744,476	260,289	50,407	11,009	3,103	2,446	10,700	.264	.333	.394	.727
14	Guardians	9,382	9,869	.487	19,342	.513	659,261	87,447	174,545	31,123	5,496	13,900	80,816	62,563	4,828	94,463	11,897	3,383	741,464	258,360	50,519	11,460	3,352	2,542	10,517	.265	.331	.392	.723
15	Red Sox	9,278	9,972	.482	19,333	.518	661,671	90,296	176,565	33,093	5,596	14,583	83,733	66,771	4,797	95,418	9,621	2,545	747,168	264,599	53,272	10,592	3,337	2,995	11,540	.267	.337	.400	.737
16	Yankees	8,161	10,796	.431	19,045	.569	649,109	92,544	172,340	28,606	5,491	17,294	85,988	68,523	4,922	94,717	11,639	2,800	735,424	263,810	51,391	9,594	3,276	2,827	10,672	.266	.339	.406	.745
17	Rangers	5,317	4,834	.524	10,157	.476	346,757	45,713	89,460	15,951	1,890	10,177	43,192	32,839	2,692	65,043	5,928	2,843	388,077	139,722	28,018	2,963	2,826	2,250	7,789	.258	.325	.403	.727
18	Mets	5,158	4,837	.516	10,003	.484	338,444	41,274	84,568	15,108	1,814	8,560	38,862	32,345	2,849	64,816	5,870	2,733	380,237	128,984	25,482	3,986	2,613	3,137	7,441	.250	.318	.381	.699
19	Angels	5,132	5,033	.505	10,168	.495	344,997	43,990	88,280	15,260	1,808	9,190	41,393	32,266	2,816	62,560	6,039	3,097	386,381	134,726	26,258	3,535	2,767	2,482	7,866	.256	.322	.391	.713
20	Astros	4,979	5,025	.498	10,009	.502	339,672	42,683	86,580	15,877	2,170	8,406	40,168	32,303	2,892	62,800	7,145	3,129	381,605	132,015	26,453	4,027	2,711	3,144	7,393	.255	.323	.389	.711
21	Padres	4,728	4,146	.533	8,876	.467	300,045	35,964	74,823	13,240	1,757	7,244	33,822	28,565	2,120	59,347	5,994	2,602	336,680	113,309	22,241	3,708	2,242	2,685	6,491	.249	.317	.378	.695
22	Royals	4,638	4,224	.523	8,864	.477	303,178	38,770	79,612	14,882	2,284	6,986	36,588	25,959	2,454	52,014	7,073	2,893	336,620	120,020	24,152	2,364	2,665	1,865	6,770	.263	.323	.396	.719
23	Nationals	4,587	4,278	.517	8,869	.483	299,968	37,151	76,119	14,679	1,788	7,588	34,917	28,205	2,613	57,046	6,528	2,770	336,943	117,138	24,055	3,876	2,281	2,880	6,490	.254	.321	.391	.712
24	Brewers	4,545	4,324	.512	8,873	.488	301,219	39,464	77,153	14,380	1,755	8,692	37,387	28,989	2,706	58,772	5,962	2,726	338,488	121,119	24,827	3,160	2,414	2,157	6,602	.256	.325	.402	.727
25	Mariners	3,962	3,617	.523	7,581	.477	258,595	33,670	66,459	12,393	1,258	7,710	31,983	24,521	2,345	49,581	5,013	2,167	289,476	104,498	21,361	1,944	2,071	1,664	5,667	.257	.325	.404	.729