Stephen Curry has the highest plus-minus in a single NBA playoff run, at +245 in 2016-17.

Interpreted as:

highest plus minus by a player in a playoff

NAME	+/-	SEASON	TM	GP	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF
Stephen Curry	+245	2016-17	GSW	17	35.4	28.1	6.2	6.7	2.0	0.2	3.4	8.9	18.4	48.4	4.2	10.1	41.9	6.1	6.7	90.4	601	477	106	114	34	4	58	37
Draymond Green	+227	2016-17	GSW	17	34.9	13.1	9.1	6.5	1.8	1.6	2.1	4.2	9.5	44.7	1.9	4.6	41.0	2.7	3.9	68.7	593	222	155	110	31	28	36	60
Kobe Bryant	+213	2000-01	LAL	16	43.4	29.4	7.3	6.1	1.6	0.8	3.2	10.5	22.4	46.9	0.7	2.1	32.4	7.8	9.4	82.1	694	471	116	97	25	12	51	53
LeBron James	+209	2015-16	CLE	21	39.1	26.3	9.5	7.6	2.3	1.3	3.6	10.4	19.9	52.5	1.5	4.5	34.0	3.9	5.9	66.1	822	552	200	160	49	27	75	54
Kevin Durant	+207	2017-18	GSW	21	38.4	29.0	7.8	4.7	0.7	1.2	2.4	10.1	20.7	48.7	2.2	6.6	34.1	6.5	7.2	90.1	807	608	163	99	15	25	50	43
Ben Wallace	+202	2003-04	DET	23	40.2	10.3	14.3	1.9	1.9	2.4	1.6	4.0	8.9	45.4	0.0	0.1	0.0	2.2	5.1	42.7	924	236	328	44	44	56	37	58
LeBron James	+199	2011-12	MIA	23	42.7	30.3	9.7	5.6	1.9	0.7	3.5	10.9	21.8	50.0	1.0	3.7	25.9	7.5	10.2	73.9	983	697	224	129	43	16	81	47
LeBron James	+195	2016-17	CLE	18	41.3	32.8	9.1	7.8	1.9	1.3	4.0	12.1	21.3	56.5	2.4	5.9	41.1	6.3	9.0	69.8	744	591	164	141	35	23	72	43
David Robinson	+194	1998-99	SAS	17	35.3	15.6	9.9	2.5	1.6	2.4	2.4	5.1	10.6	48.3	0.0	0.0		5.4	7.4	72.2	600	265	168	43	28	40	40	61
Klay Thompson	+192	2016-17	GSW	17	35.1	15.0	3.9	2.1	0.8	0.3	1.4	5.5	13.9	39.7	2.4	6.2	38.7	1.5	1.9	78.8	596	255	66	35	14	5	24	44
Draymond Green	+192	2014-15	GSW	21	37.3	13.7	10.1	5.2	1.8	1.2	2.8	4.8	11.4	41.7	1.1	4.3	26.4	3.0	4.1	73.6	784	288	212	109	38	25	58	89
Manu Ginobili	+191	2002-03	SAS	24	27.5	9.4	3.8	2.9	1.7	0.4	1.5	3.0	7.7	38.6	1.2	3.0	38.4	2.3	3.1	75.7	660	226	92	70	41	9	36	62
Lamar Odom	+189	2008-09	LAL	23	32.0	12.3	9.1	1.8	0.7	1.3	1.7	4.7	9.0	52.4	0.8	1.5	51.4	2.1	3.5	61.3	735	283	210	42	16	31	39	75
Aaron Gordon	+187	2022-23	DEN	20	35.7	13.3	6.0	2.6	0.6	0.7	1.0	5.1	9.8	51.8	0.9	2.3	39.1	2.3	3.5	65.2	713	265	120	52	11	13	20	58
Kevin Garnett	+186	2007-08	BOS	26	38.0	20.4	10.5	3.3	1.3	1.1	2.1	8.3	16.8	49.5	0.1	0.3	25.0	3.6	4.5	81.0	987	530	274	87	35	29	55	74
Shaquille O'Neal	+186	2000-01	LAL	16	42.3	30.4	15.4	3.2	0.4	2.4	3.6	11.9	21.5	55.5	0.0	0.0		6.6	12.5	52.5	676	487	247	51	7	38	57	55
Anthony Davis	+184	2019-20	LAL	21	36.6	27.7	9.7	3.5	1.2	1.4	2.5	9.8	17.1	57.1	1.1	2.9	38.3	7.1	8.5	83.2	769	582	204	73	26	30	53	56
Draymond Green	+183	2017-18	GSW	21	39.0	10.8	10.6	8.1	2.0	1.5	3.0	4.0	9.1	43.2	1.0	3.8	26.6	1.9	2.3	79.6	818	226	222	171	41	31	63	75
Dwyane Wade	+183	2011-12	MIA	23	39.4	22.8	5.2	4.3	1.7	1.3	3.0	8.6	18.5	46.2	0.4	1.5	29.4	5.3	7.2	72.9	907	525	120	100	39	30	68	65
Manu Ginobili	+182	2013-14	SAS	23	25.5	14.3	3.3	4.1	1.6	0.1	2.3	4.5	10.3	43.9	1.8	4.6	39.0	3.5	4.1	86.2	586	330	75	95	36	2	52	60
Jamal Murray	+181	2022-23	DEN	20	40.0	26.1	5.7	7.1	1.5	0.3	2.5	9.7	20.5	47.3	3.0	7.5	39.6	3.8	4.1	92.6	799	522	113	142	30	5	50	41
Kobe Bryant	+181	2008-09	LAL	23	40.9	30.2	5.3	5.5	1.7	0.9	2.6	10.5	23.0	45.7	1.6	4.6	34.9	7.6	8.6	88.3	940	695	123	126	38	21	59	59
Tim Duncan	+181	2002-03	SAS	24	42.5	24.7	15.4	5.3	0.6	3.3	3.2	9.1	17.2	52.9	0.0	0.3	0.0	6.5	9.7	67.7	1,021	593	369	127	15	79	76	78
Richard Hamilton	+178	2003-04	DET	23	40.2	21.5	4.6	4.2	1.2	0.0	3.1	7.9	17.6	44.7	0.7	1.7	38.5	5.1	6.0	84.8	924	494	106	97	27	1	72	72
Kevin Durant	+177	2016-17	GSW	15	35.5	28.5	7.9	4.3	0.8	1.3	2.5	9.9	17.9	55.6	2.5	5.7	44.2	6.1	6.9	89.3	533	428	119	64	12	20	38	39