LeBron James has the most games with 21+ points, with 1,235 games.

Interpreted as:

most regular-season game with 21 or more points by a player

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	LeBron James L. James	1,235	36,719	38.6	29.7	7.7	7.4	1.6	0.8	10.9	20.7	52.6	1.9	5.0	37.2	6.1	8.2	74.3	61.1	1.2	6.5	3.5	47,657	9,503	9,145	1,923	952	4,342	2,244	+6836
2	Karl Malone K. Malone	1,064	30,600	38.8	28.8	10.9	3.6	1.5	0.8	10.5	19.6	53.7	0.1	0.3	29.2	7.6	10.1	75.7	59.8	2.7	8.2	3.1	41,328	11,557	3,816	1,558	883	3,302	3,374	+2659
3	Kareem Abdul-Jabbar K. Abdul-Jabbar	1,049	30,724		29.3	12.8				12.1			0.0	0.0	0.0	5.1	7.1	72.2						13,434
4	Kevin Durant K. Durant	917	27,216	37.7	29.7	7.3	4.5	1.1	1.2	10.2	19.8	51.8	2.2	5.4	40.7	7.1	8.0	88.6	63.8	0.7	6.6	3.2	34,588	6,673	4,117	984	1,079	2,965	1,829	+4592
5	Michael Jordan M. Jordan	900	29,614	39.2	32.9	6.4	5.3	2.5	0.9	12.4	24.2	51.2	0.6	1.8	34.3	7.5	9.0	84.0	58.5	1.6	4.8	2.8	35,322	5,742	4,812	2,258	791	2,525	2,424	+1379
6	Kobe Bryant K. Bryant	884	27,248	39.3	30.8	5.8	4.9	1.6	0.5	10.7	22.8	47.2	1.7	4.7	35.8	7.7	9.1	84.0	57.5	1.3	4.5	3.1	34,738	5,131	4,372	1,420	454	2,773	2,315	+4179
7	Dirk Nowitzki D. Nowitzki	780	21,424	38.0	27.5	8.8	2.8	0.9	1.0	9.6	18.8	51.2	1.7	3.7	44.1	6.5	7.4	88.8	62.2	1.2	7.6	1.9	29,646	6,838	2,152	725	747	1,497	1,965	+5359
8	Shaquille O'Neal S. O'Neal	775	22,426	38.1	28.9	12.2	2.8	0.7	2.6	11.5	19.3	59.6	0.0	0.0	5.0	6.0	11.1	53.9	59.9	4.0	8.1	2.9	29,493	9,424	2,186	517	1,981	2,219	2,639	+3822
9	Carmelo Anthony C. Anthony	743	21,131	37.3	28.4	6.7	3.1	1.1	0.6	10.2	20.9	48.7	1.6	4.0	39.8	6.5	7.9	82.4	58.4	1.8	4.9	2.7	27,749	4,964	2,272	837	413	2,023	2,212	+2839
10	Wilt Chamberlain W. Chamberlain	743	27,468		37.0	24.3				15.0						7.1	13.3	53.2						18,044
11	Oscar Robertson O. Robertson	726	22,321		30.7				0.0	10.8						9.0	10.7	84.5		1.0	0.5						0
12	Dominique Wilkins D. Wilkins	722	21,768	38.3	30.1	7.5	2.8		0.6	11.2	22.9	48.9	0.8			6.9	8.4	82.6	56.6				27,660	5,382	2,031		469		1,444	-8
13	Jerry West J. West	715	21,874		30.6					11.0						8.6	10.5	82.1
14	Moses Malone M. Malone	695	19,397	38.8	27.9	14.4	1.6			9.7	18.2	53.1	0.0			8.6	10.9	78.5	60.6				26,981	10,035	1,105				1,775
15	James Harden J. Harden	693	21,498	37.4	31.0	6.3	8.2	1.7	0.6	9.1	19.6	46.6	3.6	9.2	39.1	9.1	10.5	86.9	64.0	0.9	5.4	4.3	25,943	4,356	5,670	1,191	448	2,947	1,821	+4277
16	Hakeem Olajuwon H. Olajuwon	687	19,301	39.2	28.1	12.5	2.9	1.9	3.5	11.2	20.4	54.7	0.0	0.1	20.5	5.7	7.8	73.5	58.9	3.8	8.7	3.3	26,915	8,567	1,964	1,328	2,402	2,253	2,570	+339
17	Stephen Curry S. Curry	676	20,419	35.5	30.2	5.1	6.5	1.5	0.3	10.2	20.1	50.6	5.0	10.8	46.1	4.9	5.3	91.7	67.3	0.7	4.4	3.2	23,991	3,419	4,364	1,043	175	2,175	1,475	+5546
18	Allen Iverson A. Iverson	673	20,808	42.8	30.9	3.9	6.3	2.4	0.2	10.7	23.8	44.8	1.4	4.1	34.0	8.2	10.3	79.3	54.5	0.8	3.0	3.7	28,788	2,608	4,266	1,584	118	2,475	1,329	+1819
19	Alex English A. English	671	19,424	37.2	28.9	6.0	4.5			12.0	22.4	53.6	0.0			5.0	5.9	84.0	58.0				24,990	4,047	3,017				1,925
20	Elvin Hayes E. Hayes	671	19,049		28.4					11.4			0.0			5.5	8.0	68.8
21	Elgin Baylor E. Baylor	642	20,123		31.3					11.8						7.8	9.8	79.2
22	John Havlicek J. Havlicek	641	17,372		27.1					10.8						5.6	6.8	82.7
23	DeMar DeRozan D. DeRozan	634	17,664	37.2	27.9	4.8	4.5	1.1	0.3	9.9	19.5	50.7	0.8	2.2	35.2	7.4	8.6	85.8	60.0	0.7	4.1	2.1	23,573	3,049	2,860	690	207	1,303	1,440	+1243
24	Patrick Ewing P. Ewing	620	17,345	38.5	28.0	11.2	2.2	1.1	2.9	11.0	20.2	54.1	0.0	0.1	20.0	6.0	7.9	76.0	58.9	2.7	8.5	3.3	23,861	6,956	1,346	681	1,803	2,021	2,245	+472
25	Russell Westbrook R. Westbrook	617	17,657	36.3	28.6	7.8	8.7	1.7	0.3	10.2	21.4	47.7	1.6	4.4	35.3	6.7	8.3	79.8	57.2	1.7	6.1	4.3	22,372	4,822	5,370	1,074	198	2,646	1,628	+2384