Wilt Chamberlain had the most games with more than 50 points, with 109 games.

Interpreted as:

most regular-season game by a player with more than 50 points

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	109	6,322		58.0	26.3				23.7	42.3	56.1				10.5	17.6	59.6	57.9					2,866					192
2	Michael Jordan M. Jordan	25	1,377	42.7	55.1	7.8	4.5	3.4	1.2	20.7	33.3	62.1	1.2	2.6	47.0	12.5	14.2	87.6	69.6	2.2	5.6	3.0	1,068	196	113	84	29	74	77	+31
3	Kobe Bryant K. Bryant	19	1,077	43.7	56.7	6.0	3.6	1.4	0.6	19.2	35.9	53.4	4.5	9.8	45.7	13.8	15.5	88.8	66.3	0.9	5.1	2.8	830	114	69	26	11	54	53	+235
4	James Harden J. Harden	18	1,007	40.2	55.9	7.4	8.5	2.4	0.8	17.1	30.7	55.6	7.1	14.2	50.0	14.7	16.2	90.8	74.0	1.4	5.9	5.5	723	133	153	43	14	99	60	+232
5	Elgin Baylor E. Baylor	14	780		55.7	19.2				21.1						13.6	17.4	78.2						269					51
6	Stephen Curry S. Curry	12	651	36.9	54.3	5.4	5.1	1.6	0.3	17.5	28.3	61.8	10.3	17.0	60.8	8.9	9.3	95.5	83.6	0.3	5.1	3.7	443	65	61	19	4	44	23	+136
7	LeBron James L. James	12	644	43.0	53.7	7.9	6.9	1.4	0.9	18.6	31.2	59.6	5.0	9.0	55.6	11.5	14.3	80.7	71.7	1.6	6.3	3.3	515	95	83	17	11	40	25	+102
8	Damian Lillard D. Lillard	10	576	40.2	57.6	4.8	7.4	1.6	0.3	18.0	31.6	57.0	8.3	15.3	54.2	13.3	14.0	95.0	76.3	0.4	4.4	2.4	402	48	74	16	3	24	14	+120
9	Rick Barry R. Barry	9	493	44.4	54.8	8.8	6.4	4.0		21.9	38.8	56.4				11.0	12.3	89.2	62.0	1.0	6.0	2.0	400	79	58	20		4	28
10	Kevin Durant K. Durant	8	418	45.1	52.3	8.0	5.5	1.6	0.5	17.3	30.8	56.1	5.4	9.5	56.6	12.4	14.1	87.6	70.7	1.0	7.0	4.3	361	64	44	13	4	34	20	+61
11	Allen Iverson A. Iverson	8	432	45.7	54.0	3.6	5.4	2.9	0.3	18.5	33.3	55.6	2.5	4.8	52.6	14.5	17.4	83.5	66.0	0.5	3.1	4.0	366	29	43	23	2	32	20	+48
12	Kareem Abdul-Jabbar K. Abdul-Jabbar	8	421		52.6	13.0	5.1	0.0	2.0	20.4	31.0	65.7				11.9	15.9	74.8	69.3					104	41	0	2
13	Devin Booker D. Booker	7	404	39.1	57.7	4.9	5.6	0.9	0.6	20.0	32.7	61.1	5.9	11.0	53.2	11.9	13.4	88.3	74.7	0.9	4.0	3.3	274	34	39	6	4	23	19	+36
14	Giannis Antetokounmpo G. Antetokounmpo	6	338	37.8	56.3	14.2	4.8	1.7	0.8	19.3	30.8	62.7	1.0	4.2	24.0	16.7	19.8	84.0	71.2	2.5	11.7	4.0	227	85	29	10	5	24	12	+89
15	Dominique Wilkins D. Wilkins	6	324	42.0	54.0	6.0	2.3	2.5	1.0	19.2	30.8	62.2	0.8	1.7	50.0	14.8	18.0	82.4	69.7	2.2	3.8	3.8	252	36	14	15	6	23	13
16	Joel Embiid J. Embiid	5	285	36.5	57.0	13.2	5.0	0.8	2.4	20.0	30.2	66.2	0.8	2.4	33.3	16.2	17.8	91.0	74.9	3.4	9.8	2.6	182	66	25	4	12	13	15	+68
17	Luka Dončić L. Dončić	5	288	41.0	57.6	10.8	7.4	2.0	0.6	19.6	28.6	68.5	5.6	10.8	51.9	12.8	17.0	75.3	79.8	1.2	9.6	3.8	205	54	37	10	3	19	15	+44
18	Jayson Tatum J. Tatum	5	269	40.1	53.8	8.4	4.8	0.0	0.4	17.0	28.6	59.4	7.0	11.6	60.3	12.8	14.0	91.4	77.4	1.6	6.8	2.4	201	42	24	0	2	12	13	+69
19	Bob Pettit B. Pettit	5	263		52.6					21.0	34.6	60.7				10.6	13.6	77.9	64.8										16
20	Bradley Beal B. Beal	4	219	40.4	54.8	4.3	3.5	0.8	0.3	18.8	33.0	56.8	6.3	11.5	54.3	11.0	12.5	88.0	71.1	2.0	2.3	5.5	162	17	14	3	1	22	14	-5
21	Russell Westbrook R. Westbrook	4	220	40.9	55.0	9.5	9.5	2.3	0.3	20.0	41.5	48.2	4.0	12.3	32.7	11.0	14.5	75.9	57.4	2.0	7.5	4.5	163	38	38	9	1	18	15	+18
22	Kyrie Irving K. Irving	4	226	38.0	56.5	4.5	4.8	2.8	0.3	19.0	30.5	62.3	8.3	11.8	70.2	10.3	10.8	95.3	80.2	1.3	3.3	2.5	152	18	19	11	1	10	9	+74
23	Klay Thompson K. Thompson	4	218	33.6	54.5	4.0	2.3	1.5	0.8	19.0	31.5	60.3	10.8	18.5	58.1	5.8	6.3	92.0	79.6	0.5	3.5	2.3	134	16	9	6	3	9	9	+116
24	Karl Malone K. Malone	4	220	40.8	55.0	14.5	2.5	1.8	1.0	20.0	27.8	72.1	0.3	0.3	100.0	14.8	18.5	79.7	76.6	5.0	9.5	2.3	163	58	10	7	4	9	12	+1
25	Bernard King B. King	4	219	40.0	54.8	8.3	5.0	0.5	0.0	19.3	32.3	59.7	0.0	0.3	0.0	16.3	20.0	81.3	66.7	3.5	4.8	4.3	160	33	20	2	0	17	13