The Syracuse Nationals had their highest point differential in a game versus the Knicks on December 25, 1960, with a 62 point differential.

Interpreted as:

sixers biggest point differentalwin in a regular-season game

	TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Nationals	62	12/25/1960	SYR	vs	NYK	W 162-100	240	162					65						32	37	86.5					28
2	76ers	54	11/2/1970	PHI	vs	CLE	W 141-87	240	141	54	35			52	92	56.5				37	53	69.8	61.1				23
3	76ers	53	12/16/2023	PHI	@	CHA	W 135-82	240	135	45	30	10	6	53	88	60.2	14	31	45.2	15	17	88.2	70.7	5	40	10	17
4	76ers	47	12/7/2019	PHI	vs	CLE	W 141-94	240	141	51	43	13	8	57	90	63.3	11	26	42.3	16	23	69.6	70.4	10	41	8	16
5	76ers	47	12/8/1982	PHI	vs	ATL	W 132-85	240	132	57	41	9	8	62	103	60.2	0	0		8	15	53.3	60.2	18	39	11	12
6	76ers	46	12/14/1968	PHI	vs	SFW	W 137-91	240	137	72	30			58	106	54.7				21	32	65.6	57.0				27
7	76ers	45	12/11/2023	PHI	vs	WAS	W 146-101	240	146	47	37	14	6	52	95	54.7	20	46	43.5	22	25	88.0	68.9	9	38	13	27
8	76ers	45	3/2/1980	PHI	vs	GSW	W 144-99	240	144	49	33	19	5	54	87	62.1	1	4	25.0	35	39	89.7	69.1	13	36	20	15
9	76ers	44	11/27/2023	PHI	vs	LAL	W 138-94	240	138	48	33	11	2	47	93	50.5	22	46	47.8	22	26	84.6	66.1	15	33	5	17
10	76ers	44	4/28/2021	PHI	vs	ATL	W 127-83	240	127	46	29	12	10	48	89	53.9	16	36	44.4	15	22	68.2	64.3	11	35	7	22
11	76ers	44	11/16/1968	PHI	vs	MIL	W 136-92	240	136	62	26			51	97	52.6				34	50	68.0	57.1				21
12	Nationals	44	1/31/1954	SYR	vs	NYK	W 114-70	240	114	58	38			44	90	48.9				26	37	70.3	53.6				21
13	76ers	43	1/30/2008	PHI	vs	MIL	W 112-69	240	112	45	29	9	3	44	81	54.3	2	11	18.2	22	36	61.1	57.8	12	33	8	19
14	76ers	42	1/15/2019	PHI	vs	MIN	W 149-107	240	149	54	40	6	11	55	92	59.8	21	43	48.8	18	21	85.7	73.6	8	46	15	29
15	76ers	42	3/17/2017	PHI	vs	DAL	W 116-74	240	116	55	32	8	6	42	80	52.5	12	29	41.4	20	23	87.0	64.4	9	46	16	21
16	76ers	42	10/29/1966	PHI	vs	BOS	W 138-96	240	138	74	35			50	112	44.6				38	53	71.7	51.0				26
17	76ers	41	11/11/1980	PHI	@	CHI	W 121-80	240	121	58	32	11	6	48	87	55.2	0	0		25	31	80.6	60.1	10	48	26	23
18	Nationals	41	2/21/1962	SYR	vs	PHI	W 150-109	240	150	73	25			56	112	50.0				38	42	90.5	57.5				30
19	Nationals	41	3/3/1960	SYR	vs	BOS	W 149-108	240	149					67						15	19	78.9					24
20	76ers	40	2/20/2008	PHI	vs	NYK	W 124-84	240	124	43	23	16	4	49	86	57.0	7	14	50.0	19	26	73.1	63.6	14	29	12	17
21	76ers	39	3/17/2023	PHI	@	CHA	W 121-82	240	121	62	24	9	9	46	92	50.0	10	32	31.3	19	25	76.0	58.7	14	48	13	19
22	76ers	39	3/25/1981	PHI	vs	DET	W 114-75	240	114	51	34	16	8	47	87	54.0	0	0		20	24	83.3	58.4	11	40	18	22
23	76ers	39	11/12/1976	PHI	vs	WAS	W 143-104	240	143	45	37			60	97	61.9				23	30	76.7	64.9				19
24	76ers	38	8/14/2020	PHI	@	HOU	W 134-96	240	134	51	31	8	4	49	87	56.3	18	38	47.4	18	22	81.8	69.3	8	43	16	19
25	76ers	38	11/25/1994	PHI	@	MIN	W 109-71	240	109	49	28	9	8	45	80	56.3	5	8	62.5	14	18	77.8	62.0	14	35	17	22