The Milwaukee Bucks have the lowest point differential by a team in a game 6, with a -54 point differential in Game 6 of the 2015 First Round against the Bulls.

	TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Bucks	-54	4/30/2015	MIL	vs	CHI	L 66-120	240	66	41	17	3	4	25	76	32.9	4	19	21.1	12	19	63.2	39.1	9	32	18	17
2	Nuggets	-45	5/16/2024	DEN	@	MIN	L 70-115	240	70	43	18	2	5	26	86	30.2	7	36	19.4	11	14	78.6	38.0	10	33	12	17
3	Grizzlies	-40	4/28/2023	MEM	@	LAL	L 85-125	240	85	45	19	10	2	29	96	30.2	12	38	31.6	15	20	75.0	40.6	14	31	14	17
4	Warriors	-40	4/5/1969	SFW	vs	LAL	L 78-118	240	78	61	15			31	111	27.9				16	20	80.0	32.6				18
5	Rockets	-39	5/11/2017	HOU	vs	SAS	L 75-114	240	75	37	14	5	3	22	77	28.6	13	40	32.5	18	25	72.0	42.6	10	27	13	16
6	Lakers	-39	6/17/2008	LAL	@	BOS	L 92-131	240	92	29	16	4	0	27	64	42.2	10	27	37.0	28	38	73.7	57.0	2	27	19	25
7	Celtics	-38	5/16/2025	BOS	@	NYK	L 81-119	240	81	36	19	4	3	31	86	36.0	12	40	30.0	7	10	70.0	44.8	9	27	15	22
8	Raptors	-35	4/28/2022	TOR	vs	PHI	L 97-132	240	97	37	15	6	1	35	89	39.3	7	35	20.0	20	25	80.0	48.5	15	22	9	22
9	SuperSonics	-35	5/30/1996	SEA	@	UTA	L 83-118	240	83	35	19	8	4	27	66	40.9	5	18	27.8	24	32	75.0	51.8	10	25	23	25
10	SuperSonics	-35	6/4/1978	SEA	@	WAS	L 82-117	240	82	49	18	8	9	33	98	33.7				16	27	59.3	37.3	18	31	22	27
11	Cavaliers	-34	4/27/2018	CLE	@	IND	L 87-121	240	87	33	16	4	2	33	79	41.8	12	38	31.6	9	16	56.3	50.6	7	26	14	17
12	Cavaliers	-31	5/15/1992	CLE	@	BOS	L 91-122	240	91	37	17	6	1	31	80	38.8	3	12	25.0	26	28	92.9	49.3	13	24	15	16
13	Rockets	-29	5/26/2018	HOU	@	GSW	L 86-115	240	86	38	13	8	2	31	77	40.3	15	39	38.5	9	17	52.9	50.9	7	31	21	16
14	Lakers	-28	5/15/2003	LAL	vs	SAS	L 82-110	240	82	32	24	8	4	36	80	45.0	4	18	22.2	6	13	46.2	47.8	10	22	13	24
15	Lakers	-28	5/19/1988	LAL	@	UTA	L 80-108	240	80	43	16	4	7	30	80	37.5	4	6	66.7	16	24	66.7	44.2	19	24	18	26
16	Nuggets	-28	4/30/1978	DEN	@	MIL	L 91-119	240	91	45	30	10	14	40	100	40.0				11	18	61.1	42.2	11	34	21	19
17	Warriors	-28	4/12/1964	SFW	@	STL	L 95-123	240	95	61	13			39	100	39.0				17	37	45.9	40.8				23
18	Suns	-27	5/12/2022	PHX	@	DAL	L 86-113	240	86	45	18	3	2	31	78	39.7	6	18	33.3	18	21	85.7	49.3	13	32	22	27
19	Clippers	-27	6/30/2021	LAC	vs	PHX	L 103-130	240	103	32	18	5	3	33	79	41.8	12	39	30.8	25	32	78.1	55.3	7	25	8	11
20	Nuggets	-27	5/29/2009	DEN	vs	LAL	L 92-119	240	92	27	14	7	3	32	73	43.8	8	19	42.1	20	25	80.0	54.8	7	20	13	22
21	Spurs	-27	5/16/1996	SAS	@	UTA	L 81-108	240	81	35	13	8	5	27	70	38.6	8	20	40.0	19	28	67.9	49.2	12	23	12	27
22	Magic	-27	6/2/1995	ORL	@	IND	L 96-123	240	96	32	22	5	4	37	80	46.3	12	27	44.4	10	18	55.6	54.6	8	24	11	22
23	Raptors	-26	5/27/2016	TOR	vs	CLE	L 87-113	240	87	33	10	6	2	33	79	41.8	8	25	32.0	13	17	76.5	50.3	7	26	12	19
24	Hawks	-26	5/1/2009	ATL	@	MIA	L 72-98	240	72	36	8	7	5	27	73	37.0	7	21	33.3	11	18	61.1	44.5	12	24	14	24
25	Suns	-25	5/11/2023	PHX	vs	DEN	L 100-125	240	100	29	20	3	5	38	79	48.1	11	28	39.3	13	20	65.0	56.9	2	27	14	22