Shawn Marion has the highest plus/minus in a game with 20+ rebounds, at +45 versus the Timberwolves on January 21, 2007.

Interpreted as:

highest +/- by a player in a regular-season game with 20 or more rebounds

	NAME	+/-	REB	DATE	TM		OPP	MIN	PTS	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Shawn Marion S. Marion	+45	20	1/21/2007	PHX	vs	MIN	31	17	3	1	2	8	12	66.7	1	2	50.0	0	0		70.8	4	16	0	1
2	DeAndre Jordan D. Jordan	+42	20	2/9/2014	LAC	vs	PHI	30	10	1	1	4	4	5	80.0	0	0		2	4	50.0	74.0	4	16	0	2
3	Jayson Williams J. Williams	+40	22	12/13/1997	NJN	vs	DEN	34	18	2	1	1	8	15	53.3	0	0		2	2	100.0	56.7	13	9	2	2
4	Andre Drummond A. Drummond	+39	20	2/8/2019	DET	vs	NYK	33	29	2	1	3	12	15	80.0	0	0		5	6	83.3	82.2	3	17	1	4
5	Dwight Howard D. Howard	+39	22	3/1/2008	ORL	vs	NYK	38	26	1	3	2	10	16	62.5	0	0		6	12	50.0	61.1	5	17	4	3
6	Ben Wallace B. Wallace	+39	20	4/3/2001	DET	@	CHI	36	4	4	2	5	2	5	40.0	0	0		0	0		40.0	3	17	1	3
7	Yao Ming Y. Ming	+36	22	3/11/2005	HOU	@	PHX	35	27	1	0	5	10	18	55.6	0	0		7	9	77.8	61.5	9	13	2	4
8	Mark Blount M. Blount	+36	21	3/1/2004	BOS	vs	ORL	38	28	2	2	3	13	21	61.9	0	0		2	3	66.7	62.7	7	14	2	3
9	Clint Capela C. Capela	+35	20	11/9/2019	HOU	@	CHI	42	16	1	0	4	7	10	70.0	0	0		2	2	100.0	73.5	5	15	0	3
10	Miles Plumlee M. Plumlee	+35	20	12/23/2013	PHX	vs	LAL	31	17	1	0	2	8	14	57.1	0	0		1	5	20.0	52.5	6	14	3	5
11	Ben Wallace B. Wallace	+35	20	4/17/2002	DET	vs	MIL	33	10	2	1	2	5	6	83.3	0	0		0	1	0.0	77.6	7	13	1	2
12	Dale Davis D. Davis	+35	20	12/10/1999	IND	vs	CLE	31	18	3	0	3	6	11	54.5	0	0		6	7	85.7	63.9	6	14	1	2
13	DeAndre Jordan D. Jordan	+34	20	3/7/2016	LAC	@	DAL	38	23	1	2	2	6	7	85.7	0	0		11	19	57.9	74.9	4	16	0	1
14	Nikola Jokić N. Jokić	+33	21	2/13/2017	DEN	vs	GSW	36	17	12	2	0	7	13	53.8	0	0		3	4	75.0	57.6	6	15	6	3
15	Dwight Howard D. Howard	+33	20	12/1/2004	ORL	vs	TOR	38	15	3	2	2	4	6	66.7	0	0		7	9	77.8	75.3	6	14	1	2
16	Isaiah Hartenstein I. Hartenstein	+32	20	1/3/2024	NYK	vs	CHI	37	10	1	0	5	4	6	66.7	0	0		2	3	66.7	68.3	7	13	2	2
17	Jared Sullinger J. Sullinger	+32	20	12/7/2015	BOS	@	NOP	34	11	3	1	0	4	13	30.8	1	2	50.0	2	2	100.0	39.6	4	16	5	4
18	Karl-Anthony Towns K. Towns	+31	20	12/19/2024	NYK	@	MIN	38	32	6	2	0	10	12	83.3	5	5	100.0	7	9	77.8	100.3	3	17	4	2
19	Rudy Gobert R. Gobert	+31	20	12/6/2023	MIN	vs	SAS	30	16	2	0	2	7	8	87.5	0	0		2	2	100.0	90.1	5	15	1	3
20	Rudy Gobert R. Gobert	+31	21	1/6/2023	MIN	vs	LAC	36	25	0	0	2	11	15	73.3	0	0		3	5	60.0	72.7	7	14	5	2
21	Deandre Ayton D. Ayton	+31	21	1/16/2020	PHX	@	NYK	35	26	2	0	2	11	15	73.3	0	0		4	4	100.0	77.6	6	15	2	2
22	Clint Capela C. Capela	+31	25	2/9/2018	HOU	vs	DEN	29	23	0	0	2	9	15	60.0	0	0		5	11	45.5	58.0	7	18	1	1
23	Shawn Bradley S. Bradley	+31	20	3/9/2001	DAL	vs	GSW	37	12	2	1	5	5	12	41.7	0	0		2	2	100.0	46.6	6	14	1	4
24	Clint Capela C. Capela	+30	20	11/18/2019	HOU	vs	POR	35	22	0	1	4	10	17	58.8	0	0		2	3	66.7	60.0	5	15	1	3
25	Karl-Anthony Towns K. Towns	+30	20	12/26/2018	MIN	@	CHI	35	20	4	0	0	8	13	61.5	2	2	100.0	2	3	66.7	69.8	4	16	3	3