Drew Brees has the highest completion percentage by a quarterback in a game with 20+ completions, at 96.7 percent against the Colts on December 16, 2019.

highest completion percentage in a game by quarterback with at least 20 completions
Interpreted as:
highest completion percentage in a regular-season game by quarterback with at least 20 completions
12/16/2019Brees11/25/2018Rivers11/26/2018Mariota9/20/2009Warner12/26/1993Testaverde11/10/1974Anderson9/16/2018Carr10/8/2018Brees11/11/2002Gannon12/29/2013Manning12/18/2016Prescott9/24/2006Brunell9/13/2020Wilson10/23/2011Brees10/24/2019Cousins11/13/2011Romo12/27/2009Brady9/24/1995Chandler9/8/2019Minshew11/11/2018Brees11/8/2018Roethlisberger12/21/2015Stafford11/22/2009Favre96.796.695.792.391.390.990.689.789.589.388.988.988.688.688.588.588.588.588.088.088.088.088.0
NAMEDATETMOPPPCTCMPATTYDSAVGTDTD%INTINT%SCKSCKYRATE
Drew BreesDrew Brees12/16/2019NONOvs. IND
vs.
96.7293030710.2413.300.000148.9
Philip RiversPhilip Rivers11/25/2018LACLACvs. ARI
vs.
96.628292598.9310.300.0423138.4
Marcus MariotaMarcus Mariota11/26/2018TENTEN@ HOU
@
95.7222330313.228.700.0643147.7
Kurt WarnerKurt Warner9/20/2009ARIARI@ JAX
@
92.324262439.327.700.000131.3
Vinny TestaverdeVinny Testaverde12/26/1993CLECLE@ RAM
@
91.321232169.428.700.013134.8
Ken AndersonKen Anderson11/10/1974CINCINvs. PIT
vs.
90.9202222710.300.000.0109.7
Derek CarrDerek Carr9/16/2018OAKOAK@ DEN
@
90.629322889.013.100.017114.6
Drew BreesDrew Brees10/8/2018NONOvs. WAS
vs.
89.7262936312.5310.300.0214153.2
Rich GannonRich Gannon11/11/2002OAKOAK@ DEN
@
89.534383529.337.900.015131.6
Peyton ManningPeyton Manning12/29/2013DENDEN@ OAK
@
89.325282669.5414.300.019145.8
Dak PrescottDak Prescott12/18/2016DALDALvs. TB
vs.
88.932362797.800.000.031599.0
Mark BrunellMark Brunell9/24/2006WASWAS@ HOU
@
88.924272619.713.700.000119.3
Russell WilsonRussell Wilson9/13/2020SEASEA@ ATL
@
88.631353229.2411.400.0323143.1
Drew BreesDrew Brees10/23/2011NONOvs. IND
vs.
88.631353259.3514.300.024144.9
Kirk CousinsKirk Cousins10/24/2019MINMINvs. WAS
vs.
88.5232628511.000.000.0312112.3
Tony RomoTony Romo11/13/2011DALDALvs. BUF
vs.
88.5232627010.4311.500.000148.4
Tom BradyTom Brady12/27/2009NENEvs. JAX
vs.
88.5232626710.3415.400.000149.0
Chris ChandlerChris Chandler9/24/1995HOUHOU@ CIN
@
88.5232635213.5415.400.012158.3
Gardner MinshewGardner Minshew9/8/2019JAXJAXvs. KC
vs.
88.0222527511.028.014.013122.5
Drew BreesDrew Brees11/11/2018NONO@ CIN
@
88.0222526510.6312.000.000150.4
Ben RoethlisbergerBen Roethlisberger11/8/2018PITPITvs. CAR
vs.
88.0222532813.1520.000.016158.3
Matthew StaffordMatthew Stafford12/21/2015DETDET@ NO
@
88.0222525410.2312.000.038148.6
Brett FavreBrett Favre11/22/2009MINMINvs. SEA
vs.
88.022252138.5416.000.0219141.8
Drew BreesDrew Brees10/31/2004SDSDvs. OAK
vs.
88.0222528111.2520.000.018153.1
Vinny TestaverdeVinny Testaverde9/13/1992TBTBvs. GB
vs.
88.0222536314.528.000.0430145.4
Results may be incomplete. StatMuse has complete game-level data for completion percentage and completions going back to the 1950 season.

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