The Baltimore Orioles have the highest run differential by a team in a game, with a differential of 22 runs against the Blue Jays on September 28, 2000.
Interpreted as:
largest point differential in a baseball regular-season game by the orioles franchise ever| TEAM | DIFF | DATE | TM | OPP | RESULT | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Orioles | 22 | 9/28/2000 | vs | W 23-1 | 47 | 23 | 23 | 2 | 0 | 3 | 20 | 5 | 1 | 5 | 0 | 0 | 54 | 34 | 5 | 0 | 1 | 0 | 1 | .489 | .537 | .723 | 1.260 | ||
| 2 | | Orioles | 21 | 6/13/1999 | @ | W 22-1 | 51 | 22 | 25 | 7 | 0 | 4 | 22 | 6 | 0 | 8 | 0 | 0 | 57 | 44 | 11 | 0 | 0 | 0 | 0 | .490 | .544 | .863 | 1.407 | ||
| 3 |  | Orioles | 18 | 7/26/2025 | vs | W 18-0 | 40 | 18 | 18 | 4 | 0 | 3 | 16 | 6 | 1 | 4 | 1 | 0 | 47 | 31 | 7 | 0 | 0 | 0 | 3 | .450 | .532 | .775 | 1.307 | ||
| 4 | | Orioles | 17 | 7/27/1969 | vs | W 17-0 | 42 | 17 | 20 | 3 | 2 | 4 | 17 | 5 | 0 | 6 | 0 | 1 | 48 | 39 | 9 | 1 | 0 | 0 | 0 | .476 | .532 | .929 | 1.460 | ||
| 5 | | Orioles | 16 | 5/13/2018 | vs | W 17-1 | 44 | 17 | 19 | 3 | 1 | 4 | 17 | 5 | 0 | 5 | 0 | 0 | 49 | 36 | 8 | 0 | 0 | 0 | 0 | .432 | .490 | .818 | 1.308 | ||
| 6 | | Orioles | 16 | 8/16/2015 | vs | W 18-2 | 48 | 18 | 26 | 7 | 0 | 4 | 18 | 3 | 0 | 8 | 0 | 0 | 51 | 45 | 11 | 0 | 0 | 0 | 1 | .542 | .569 | .938 | 1.506 | ||
| 7 | | Orioles | 16 | 6/16/2015 | vs | W 19-3 | 39 | 19 | 17 | 2 | 0 | 8 | 17 | 8 | 1 | 7 | 0 | 0 | 49 | 43 | 10 | 0 | 1 | 0 | 2 | .436 | .531 | 1.103 | 1.633 | ||
| 8 | | Orioles | 16 | 8/10/1999 | @ | W 17-1 | 47 | 17 | 20 | 6 | 1 | 0 | 15 | 8 | 2 | 5 | 0 | 0 | 58 | 28 | 7 | 0 | 1 | 0 | 2 | .426 | .517 | .596 | 1.113 | ||
| 9 | | Orioles | 16 | 4/29/1970 | @ | W 18-2 | 48 | 18 | 20 | 2 | 0 | 5 | 17 | 7 | 0 | 5 | 0 | 0 | 55 | 37 | 7 | 0 | 0 | 0 | 0 | .417 | .491 | .771 | 1.262 | ||
| 10 |  | Browns | 16 | 9/9/1922 | vs | W 16-0 | 43 | 16 | 20 | 3 | 5 | 1 | 15 | 4 | 2 | 3 | 0 | 0 | 49 | 36 | 9 | 0 | .465 | .531 | .837 | 1.368 | |||||
| 11 | | Orioles | 15 | 8/19/2006 | vs | W 15-0 | 36 | 15 | 12 | 5 | 0 | 3 | 14 | 4 | 1 | 8 | 0 | 0 | 41 | 26 | 8 | 0 | 0 | 1 | 1 | .333 | .415 | .722 | 1.137 | ||
| 12 | | Browns | 15 | 8/27/1944 | @ | W 17-2 | 45 | 17 | 17 | 2 | 0 | 1 | 15 | 6 | 0 | 3 | 1 | 0 | 52 | 22 | 3 | 1 | 0 | .378 | .451 | .489 | .940 | ||||
| 13 | | Browns | 15 | 8/7/1922 | vs | W 16-1 | 42 | 16 | 19 | 5 | 2 | 3 | 14 | 3 | 0 | 3 | 1 | 0 | 47 | 37 | 10 | 2 | .452 | .489 | .881 | 1.370 | |||||
| 14 | | Browns | 15 | 9/11/1920 | vs | W 17-2 | 44 | 17 | 21 | 7 | 1 | 2 | 17 | 4 | 1 | 4 | 2 | 0 | 50 | 36 | 10 | 1 | .477 | .531 | .818 | 1.349 | |||||
| 15 | | Browns | 15 | 10/8/1911 | vs | W 17-2 | 43 | 17 | 21 | 8 | 2 | 0 | 1 | 0 | 1 | 47 | 33 | 10 | 3 | .488 | .500 | .767 | 1.267 | ||||||||
| 16 |  | Brewers | 15 | 8/5/1901 | vs | W 19-4 | 45 | 19 | 17 | 3 | 1 | 2 | 12 | 1 | 1 | -9 | 6 | -10 | 50 | 28 | 6 | 3 | -10 | -10 | .378 | .404 | .622 | 1.026 | |||
| 17 | | Orioles | 14 | 6/27/2025 | vs | W 22-8 | 46 | 22 | 21 | 9 | 1 | 4 | 20 | 8 | 1 | 9 | 2 | 0 | 55 | 44 | 14 | 0 | 0 | 0 | 0 | .457 | .545 | .957 | 1.502 | ||
| 18 | | Orioles | 14 | 5/1/1992 | vs | W 15-1 | 35 | 15 | 11 | 2 | 0 | 5 | 15 | 13 | 0 | 9 | 0 | 0 | 48 | 28 | 7 | 0 | 0 | 0 | 0 | .314 | .500 | .800 | 1.300 | ||
| 19 |  | Orioles | 14 | 8/26/1985 | @ | W 17-3 | 43 | 17 | 17 | 1 | 0 | 7 | 16 | 6 | 1 | 9 | 0 | 0 | 51 | 39 | 8 | 0 | 1 | 0 | 1 | .395 | .471 | .907 | 1.378 | ||
| 20 | | Orioles | 14 | 9/20/1984 | vs | W 15-1 | 44 | 15 | 20 | 8 | 0 | 2 | 15 | 6 | 0 | 11 | 1 | 0 | 50 | 34 | 10 | 0 | 0 | 1 | 0 | .455 | .520 | .773 | 1.293 | ||
| 21 | | Orioles | 14 | 9/28/1973 | vs | W 18-4 | 34 | 18 | 14 | 3 | 0 | 1 | 17 | 15 | 0 | 5 | 3 | 1 | 50 | 20 | 4 | 0 | 1 | 1 | 2 | .412 | .580 | .588 | 1.168 | ||
| 22 | | Orioles | 14 | 5/12/1967 | @ | W 14-0 | 43 | 14 | 17 | 2 | 0 | 0 | 14 | 9 | 1 | 8 | 1 | 0 | 54 | 19 | 2 | 1 | 0 | 2 | 0 | .395 | .509 | .442 | .951 | ||
| 23 | | Orioles | 14 | 4/22/1965 | @ | W 18-4 | 47 | 18 | 20 | 1 | 1 | 3 | 17 | 4 | 1 | 4 | 2 | 1 | 52 | 32 | 5 | 0 | 0 | 0 | 0 | .426 | .481 | .681 | 1.162 | ||
| 24 | | Orioles | 14 | 9/27/1960 | @ | W 17-3 | 44 | 17 | 18 | 3 | 1 | 4 | 16 | 8 | 0 | 7 | 0 | 0 | 53 | 35 | 8 | 0 | 1 | 0 | 1 | .409 | .491 | .795 | 1.286 | ||
| 25 | | Browns | 14 | 6/8/1940 | @ | W 15-1 | 42 | 15 | 14 | 2 | 1 | 2 | 13 | 8 | 0 | 6 | 0 | 0 | 51 | 24 | 5 | 1 | 1 | .333 | .440 | .571 | 1.011 | ||||
BAL
TOR
ATL
BAL
COL
CWS
TBR
OAK
TBD
SLA
TOR
WSH
MIL
SEA
BAL
CAL
BOS
CLE
WSH
BOS
PHASome of the information used here was obtained free of charge from Retrosheet.
More Orioles Stats
Team Batting Leaders 
HR
17
Henderson
RBI
68
Henderson
AVG
.290
Laureano
Team Pitching Leaders
W
11
Kremer
K
142
Kremer
ERA
1.81
Rogers
Team Rankings
HR
191
11th
R
677
24th
SO
1,351
18th
ERA
4.60
26th
MIN
TEX
MLB 2025 Batting Leaders
MLB 2025 Pitching Leaders
MLB Fantasy 2025
MLB 2025 Betting
MLB 2025 Standings
| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Phillies - y | 96 | 66 | .593 | |
83 | 79 | .512 | 13.0 | |
79 | 83 | .488 | 17.0 | |
76 | 86 | .469 | 20.0 | |
66 | 96 | .407 | 30.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 97 | 65 | .599 | |
 Cubs - w | 92 | 70 | .568 | 5.0 |
 Reds - w | 83 | 79 | .512 | 14.0 |
78 | 84 | .481 | 19.0 | |
71 | 91 | .438 | 26.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 93 | 69 | .574 | |
 Padres - w | 90 | 72 | .556 | 3.0 |
81 | 81 | .500 | 12.0 | |
80 | 82 | .494 | 13.0 | |
43 | 119 | .265 | 50.0 |
Mets
Marlins
Nationals
Cardinals
Pirates
Giants
Diamondbacks| AL East | W | L | PCT | GB |
|---|---|---|---|---|
 Blue Jays - y | 94 | 68 | .580 | |
 Yankees - w | 94 | 68 | .580 | |
 Red Sox - w | 89 | 73 | .549 | 5.0 |
77 | 85 | .475 | 17.0 | |
75 | 87 | .463 | 19.0 | |
| AL Central | W | L | PCT | GB |
 Guardians - y | 88 | 74 | .543 | |
 Tigers - w | 87 | 75 | .537 | 1.0 |
82 | 80 | .506 | 6.0 | |
70 | 92 | .432 | 18.0 | |
60 | 102 | .370 | 28.0 | |
| AL West | W | L | PCT | GB |
 Mariners - y | 90 | 72 | .556 | |
87 | 75 | .537 | 3.0 | |
81 | 81 | .500 | 9.0 | |
76 | 86 | .469 | 14.0 | |
72 | 90 | .444 | 18.0 |
Royals
Astros
Angels
