The Oklahoma City Thunder had their lowest point differential in a game versus the Grizzlies on December 2, 2021, with a -73 point differential.

Interpreted as:

okc thunder largest loss in a regular-season game in history

	TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Thunder	-73	12/2/2021	OKC	@	MEM	L 79-152	240	79	26	14	2	5	25	76	32.9	11	38	28.9	18	22	81.8	46.1	8	18	19	14
2	Thunder	-57	5/1/2021	OKC	vs	IND	L 95-152	240	95	48	23	8	4	38	111	34.2	8	38	21.1	11	23	47.8	39.2	21	27	14	15
3	SuperSonics	-52	3/16/2008	SEA	@	DEN	L 116-168	240	116	45	28	12	8	46	107	43.0	2	10	20.0	22	32	68.8	47.9	18	27	16	24
4	Thunder	-50	4/10/2022	OKC	@	LAC	L 88-138	240	88	40	17	6	2	37	98	37.8	9	34	26.5	5	9	55.6	43.2	12	28	8	16
5	Thunder	-48	4/3/2021	OKC	@	POR	L 85-133	240	85	46	17	4	6	30	85	35.3	8	34	23.5	17	24	70.8	44.5	12	34	22	21
6	Thunder	-47	2/28/2020	OKC	@	MIL	L 86-133	240	86	36	14	8	3	33	91	36.3	6	35	17.1	14	20	70.0	43.1	5	31	14	15
7	SuperSonics	-47	11/20/1968	SEA	vs	BOS	L 92-139	240	92	50	19			36	105	34.3				20	26	76.9	39.5				25
8	SuperSonics	-44	4/11/1985	SEA	vs	DAL	L 80-124	240	80	41	24	4	2	36	93	38.7	1	7	14.3	7	14	50.0	40.3	12	29	19	15
9	SuperSonics	-44	12/19/1972	SEA	@	MIL	L 77-121	240	77	51	18			34	100	34.0				9	14	64.3	36.3				23
10	Thunder	-42	1/7/2009	OKC	@	MIN	L 87-129	240	87	38	23	4	4	35	88	39.8	3	11	27.3	14	16	87.5	45.8	7	31	15	19
11	SuperSonics	-42	2/27/2008	SEA	vs	DEN	L 96-138	240	96	42	15	10	1	37	102	36.3	3	11	27.3	19	22	86.4	43.0	19	23	16	15
12	SuperSonics	-41	3/25/2007	SEA	vs	SAS	L 79-120	240	79	37	10	6	6	26	71	36.6	3	12	25.0	24	30	80.0	46.9	12	25	17	22
13	SuperSonics	-41	11/11/2005	SEA	@	WAS	L 96-137	240	96	38	20	6	1	31	78	39.7	7	23	30.4	27	37	73.0	50.9	15	23	17	33
14	SuperSonics	-40	2/5/2003	SEA	@	BOS	L 74-114	240	74	43	19	2	6	29	80	36.3	2	12	16.7	14	17	82.4	42.3	12	31	11	11
15	SuperSonics	-40	4/13/1997	SEA	@	HOU	L 73-113	240	73	45	16	8	2	29	92	31.5	4	20	20.0	11	17	64.7	36.7	18	27	16	20
16	Thunder	-39	5/8/2021	OKC	@	GSW	L 97-136	240	97	41	21	10	1	38	94	40.4	9	37	24.3	12	20	60.0	47.2	11	30	13	16
17	Thunder	-39	3/25/2015	OKC	@	SAS	L 91-130	240	91	37	16	7	1	36	90	40.0	6	18	33.3	13	14	92.9	47.3	10	27	10	15
18	SuperSonics	-39	12/11/1973	SEA	@	MIL	L 91-130	240	91	41	16		3	35	108	32.4				21	29	72.4	37.7				19
19	Thunder	-38	4/14/2021	OKC	vs	GSW	L 109-147	240	109	50	22	6	2	44	92	47.8	7	27	25.9	14	25	56.0	52.9	17	33	21	22
20	SuperSonics	-38	3/15/1972	SEA	@	ATL	L 96-134	240	96	38	11			40	97	41.2				16	23	69.6	44.8				18
21	SuperSonics	-38	2/2/1968	SEA	@	LAL	L 113-151	240	113	49	17			43	103	41.7				27	38	71.1	47.2				35
22	SuperSonics	-38	12/20/1967	SEA	vs	PHI	L 122-160	240	122	57	25			55	127	43.3				12	16	75.0	45.5				36
23	Thunder	-37	3/4/2022	OKC	vs	MIN	L 101-138	240	101	39	19	12	4	37	86	43.0	9	35	25.7	18	21	85.7	53.0	8	31	23	16
24	Thunder	-37	4/2/2021	OKC	@	PHX	L 103-140	240	103	38	19	6	3	35	89	39.3	15	38	39.5	18	23	78.3	52.0	11	27	16	17
25	Thunder	-36	4/6/2022	OKC	@	UTA	L 101-137	240	101	32	27	9	1	37	90	41.1	16	37	43.2	11	17	64.7	51.8	11	21	10	22