Nate McMillan has the highest career +/- per minute played when playing 500+ minutes, with 0.26.

Interpreted as:

best +/-/min by a player with at least 500 minutes

	NAME	+/-/MIN	MIN	+/-	GP	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	PTS	REB	AST	STL	BLK	TOV	PF
1	Nate McMillan N. McMillan	0.26	1,077	+280	55	19.6	4.2	2.9	3.5	1.3	0.2	1.5	3.9	38.9	0.8	2.1	36.4	0.4	0.5	66.7	50.4	0.5	2.4	0.8	231	158	195	72	10	44	119
2	Jeff Hornacek J. Hornacek	0.22	8,620	+1905	287	30.0	13.5	3.0	3.8	1.2	0.2	4.8	10.0	48.4	0.8	1.9	42.1	3.0	3.4	90.3	58.9	0.7	2.3	1.6	3,870	853	1,104	351	71	461	607
3	Sam Hauser S. Hauser	0.22	4,730	+1037	256	18.5	7.4	2.9	0.9	0.4	0.2	2.6	5.8	45.1	2.0	4.9	42.0	0.2	0.2	85.1	63.2	0.5	2.4	0.3	1,894	733	227	111	61	87	292
4	Chet Holmgren C. Holmgren	0.22	3,290	+716	114	28.9	16.1	7.9	2.3	0.7	2.3	5.9	11.4	51.9	1.5	4.1	37.2	2.8	3.6	78.0	62.3	1.6	6.4	1.6	1,836	905	263	76	261	187	269
5	Ajay Mitchell A. Mitchell	0.21	597	+127	36	16.6	6.5	1.9	1.8	0.7	0.1	2.5	5.1	49.5	0.6	1.7	38.3	0.8	1.0	82.9	58.7	0.5	1.4	0.8	234	68	64	25	4	29	68
6	Isaiah Joe I. Joe	0.21	5,436	+1142	321	16.9	7.6	2.0	1.1	0.5	0.1	2.5	5.9	43.1	1.8	4.5	40.2	0.7	0.8	83.7	60.6	0.3	1.7	0.5	2,434	643	361	168	46	154	386
7	Manu Ginobili M. Ginobili	0.2	26,859	+5468	1,057	25.4	13.3	3.5	3.8	1.3	0.3	4.3	9.7	44.7	1.4	3.8	36.9	3.2	3.9	82.7	58.2	0.6	2.8	2.0	14,043	3,697	4,001	1,392	319	2,116	2,212
8	Kawhi Leonard K. Leonard	0.2	23,281	+4597	733	31.8	20.1	6.4	3.1	1.7	0.6	7.3	14.6	49.9	1.6	4.1	39.2	3.9	4.5	86.0	60.4	1.2	5.2	1.7	14,733	4,662	2,236	1,255	471	1,212	1,225
9	Gui Santos G. Santos	0.19	954	+181	79	12.1	3.9	2.8	1.2	0.4	0.2	1.4	3.0	47.0	0.6	1.6	33.8	0.6	0.7	76.3	59.4	1.1	1.7	0.6	309	221	94	29	12	49	114
10	Neemias Queta N. Queta	0.19	1,345	+253	110	12.2	4.7	3.6	0.7	0.3	0.7	2.0	3.2	62.7	0.0	0.0	0.0	0.7	1.0	71.3	64.9	1.5	2.2	0.5	521	400	72	32	73	60	181
11	Tim Duncan T. Duncan	0.19	47,368	+8910	1,392	34.0	19.0	10.8	3.0	0.7	2.2	7.4	14.6	50.6	0.0	0.1	17.9	4.2	6.1	69.6	55.1	2.8	8.1	2.4	26,496	15,091	4,225	1,025	3,020	3,381	3,304
12	David Robinson D. Robinson	0.19	13,065	+2454	430	30.4	15.2	9.1	1.7	1.1	2.2	5.4	10.7	50.2	0.0	0.0	12.5	4.4	6.2	71.3	56.5	2.7	6.4	1.8	6,530	3,934	723	454	948	791	1,134
13	John Stockton J. Stockton	0.19	15,834	+2941	524	30.2	12.3	2.8	8.6	1.7	0.2	4.4	8.5	51.2	0.6	1.4	39.5	3.0	3.6	83.7	60.7	0.6	2.1	2.5	6,426	1,446	4,496	900	114	1,291	1,218
14	Draymond Green D. Green	0.18	25,282	+4597	881	28.7	8.7	6.9	5.6	1.3	1.0	3.2	7.1	44.9	0.8	2.6	32.0	1.4	2.0	71.0	54.1	1.1	5.8	2.3	7,665	6,087	4,948	1,183	888	2,027	2,536
15	Jayson Tatum J. Tatum	0.18	20,185	+3645	585	34.5	23.6	7.3	3.8	1.1	0.7	8.2	17.8	45.9	2.6	7.1	37.0	4.5	5.4	84.0	58.3	0.9	6.5	2.4	13,784	4,293	2,243	640	384	1,389	1,232
16	Stephen Curry S. Curry	0.18	34,974	+6177	1,026	34.1	24.7	4.7	6.4	1.5	0.3	8.4	17.9	47.1	4.0	9.3	42.3	3.9	4.3	91.1	62.5	0.7	4.0	3.1	25,386	4,819	6,540	1,553	265	3,187	2,310
17	Joel Embiid J. Embiid	0.17	14,408	+2490	452	31.9	27.7	11.0	3.7	0.9	1.6	9.1	18.2	50.1	1.2	3.5	33.9	8.3	10.0	82.8	61.3	2.2	8.8	3.4	12,523	4,987	1,658	411	738	1,547	1,369
18	Nikola Jokić N. Jokić	0.17	23,639	+4071	745	31.7	21.8	10.9	7.2	1.3	0.7	8.4	15.0	56.0	1.1	3.0	36.0	3.9	4.8	82.4	63.8	2.7	8.3	2.9	16,210	8,141	5,383	949	536	2,177	1,996
19	Tiago Splitter T. Splitter	0.17	6,812	+1148	355	19.2	7.9	5.0	1.2	0.6	0.6	3.0	5.4	55.5	0.0	0.0	14.3	1.9	2.7	69.7	59.8	1.6	3.4	1.1	2,816	1,779	423	198	209	384	685
20	Isaiah Hartenstein I. Hartenstein	0.17	7,376	+1222	379	19.5	6.8	6.4	2.0	0.7	0.9	2.8	4.8	59.2	0.1	0.3	25.5	1.1	1.6	68.6	62.2	2.2	4.2	1.1	2,584	2,423	757	272	351	412	962
21	Danny Green D. Green	0.17	20,897	+3449	832	25.1	8.7	3.4	1.5	1.0	0.8	3.1	7.3	42.1	1.9	4.7	40.0	0.6	0.8	80.5	56.8	0.6	2.8	1.0	7,204	2,827	1,277	853	634	825	1,454
22	Arvydas Sabonis A. Sabonis	0.16	9,640	+1559	397	24.3	11.5	7.2	2.1	0.8	1.0	4.3	8.7	49.1	0.2	0.8	31.2	2.8	3.5	79.3	56.5	1.5	5.7	1.7	4,571	2,848	834	306	416	683	1,079
23	Shaquille O'Neal S. O'Neal	0.16	30,754	+4887	912	33.7	22.6	10.3	2.5	0.5	2.1	8.9	15.3	58.3	0.0	0.0	0.0	4.8	9.1	52.1	58.5	3.3	7.1	2.7	20,577	9,408	2,310	496	1,908	2,422	3,093
24	Michael Porter Jr. M. Porter Jr.	0.16	10,036	+1592	345	29.1	16.2	6.4	1.4	0.6	0.6	6.2	12.3	50.0	2.4	6.0	40.6	1.5	1.9	79.5	61.8	1.4	5.0	1.2	5,597	2,209	485	206	201	402	666
25	Lucas Nogueira L. Nogueira	0.16	1,754	+278	141	12.4	3.2	2.8	0.5	0.6	1.0	1.3	2.0	63.2	0.1	0.2	26.5	0.5	0.8	64.0	65.9	0.9	1.9	0.5	446	388	72	89	144	75	221