Joel Embiid had the most games with 35+ points in 2021-22, with 22 games.

Interpreted as:

most 35+ point games by a player in 2021-22

NAME	GP	PTS	SEASON	TM	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	REB	AST	STL	BLK	TOV	PF	+/-
Joel Embiid	22	880	2021-22	PHI	36.0	40.0	13.6	4.2	1.0	1.8	3.4	13.0	22.8	57.0	1.7	3.8	44.6	12.3	14.9	82.6	792	300	93	22	40	75	61	+201
DeMar DeRozan	20	766	2021-22	CHI	38.0	38.3	5.7	5.1	0.9	0.1	2.7	14.1	23.1	61.0	0.9	1.8	48.6	9.4	10.5	89.0	759	114	101	17	2	53	49	+72
Trae Young	16	661	2021-22	ATL	36.2	41.3	3.8	9.9	0.9	0.1	4.2	13.3	23.6	56.5	5.2	10.4	49.7	9.5	10.4	91.0	579	60	159	14	1	67	28	+136
Giannis Antetokounmpo	15	616	2021-22	MIL	35.1	41.1	12.8	5.7	1.2	1.1	3.3	14.3	21.3	67.2	1.7	3.9	44.8	10.7	14.4	74.1	526	192	85	18	17	49	50	+119
Luka Doncic	13	523	2021-22	DAL	37.8	40.2	10.5	7.8	1.2	0.7	4.7	14.0	26.2	53.5	5.2	11.2	46.2	7.1	9.0	78.6	491	136	102	16	9	61	28	+55
LeBron James	13	524	2021-22	LAL	38.1	40.3	9.4	6.2	0.8	1.2	3.2	15.2	26.2	57.9	4.2	9.1	45.8	5.8	7.2	81.7	495	122	80	11	15	41	24	0
Nikola Jokic	13	501	2021-22	DEN	37.2	38.5	15.4	7.8	1.8	1.3	4.5	15.2	23.4	65.1	1.3	3.5	37.0	6.8	8.5	79.3	484	200	102	23	17	58	37	+151
Devin Booker	13	506	2021-22	PHX	37.0	38.9	5.1	4.2	1.0	0.5	2.2	14.2	24.6	57.5	3.8	8.5	45.5	6.8	8.1	83.8	482	66	55	13	6	28	33	+112
Jayson Tatum	13	527	2021-22	BOS	37.6	40.5	6.9	5.2	1.3	0.8	2.2	14.3	25.2	56.9	5.4	11.5	47.0	6.5	7.2	91.4	489	90	68	17	10	28	30	+214
Kevin Durant	13	537	2021-22	BKN	39.9	41.3	7.8	6.3	1.2	1.0	4.5	14.4	25.1	57.4	3.6	7.5	48.0	8.9	9.5	93.5	519	101	82	16	13	59	25	+53
Ja Morant	13	522	2021-22	MEM	37.0	40.2	6.1	6.3	1.1	0.5	4.2	14.7	27.3	53.8	2.5	5.5	45.1	8.3	10.6	78.3	481	79	82	14	6	55	26	+46
Donovan Mitchell	11	403	2021-22	UTA	35.9	36.6	4.2	5.6	1.5	0.1	3.5	12.8	24.4	52.6	5.3	12.2	43.3	5.7	6.5	87.5	395	46	62	16	1	38	30	+77
Stephen Curry	11	455	2021-22	GSW	36.9	41.4	5.5	6.5	1.5	0.5	3.2	13.5	24.9	54.0	7.6	15.7	48.6	6.8	6.9	98.7	406	61	72	17	5	35	23	+151
Kyrie Irving	6	268	2021-22	BKN	39.3	44.7	4.3	5.7	1.8	0.7	2.7	15.3	24.5	62.6	6.2	10.5	58.7	7.8	8.7	90.4	236	26	34	11	4	16	19	+73
Karl-Anthony Towns	6	249	2021-22	MIN	36.3	41.5	13.0	3.5	0.7	0.7	3.3	13.8	23.3	59.3	3.8	7.8	48.9	10.0	11.7	85.7	218	78	21	4	4	20	20	+72
James Harden	5	187	2021-22	BKN	39.0	37.4	8.6	11.2	1.4	1.4	4.4	11.2	23.4	47.9	4.0	9.6	41.7	11.0	12.8	85.9	195	43	56	7	7	22	19	+67
Anthony Edwards	5	212	2021-22	MIN	38.4	42.4	6.2	3.6	2.2	1.0	2.8	14.6	25.6	57.0	7.0	13.4	52.2	6.2	8.8	70.5	192	31	18	11	5	14	10	+60
Klay Thompson	4	152	2021-22	GSW	36.1	38.0	5.3	3.0	0.3	0.5	2.0	14.8	26.8	55.1	8.0	15.3	52.5	0.5	0.8	66.7	144	21	12	1	2	8	8	+43
Pascal Siakam	4	147	2021-22	TOR	39.7	36.8	9.5	6.5	1.8	0.5	1.8	14.8	24.8	59.6	2.5	6.3	40.0	4.8	5.8	82.6	159	38	26	7	2	7	17	+5
Shai Gilgeous-Alexander	3	112	2021-22	OKC	36.2	37.3	6.3	5.7	1.7	1.3	4.3	12.3	22.0	56.1	1.7	5.3	31.3	11.0	14.0	78.6	109	19	17	5	4	13	9	-37
Damian Lillard	3	121	2021-22	POR	38.1	40.3	2.0	7.3	0.7	1.0	2.7	11.7	21.3	54.7	5.7	11.7	48.6	11.3	12.0	94.4	114	6	22	2	3	8	2	+17
Zach LaVine	3	110	2021-22	CHI	38.2	36.7	4.3	3.3	0.7	0.3	3.7	12.3	23.0	53.6	5.0	10.7	46.9	7.0	7.7	91.3	114	13	10	2	1	11	4	+13
Jerami Grant	3	111	2021-22	DET	35.7	37.0	3.7	2.3	0.7	1.0	1.3	12.3	23.3	52.9	5.3	9.0	59.3	7.0	8.7	80.8	107	11	7	2	3	4	5	+8
Kelly Oubre Jr.	3	111	2021-22	CHA	36.4	37.0	5.0	2.3	2.7	0.3	1.3	12.7	19.7	64.4	7.7	12.3	62.2	4.0	4.7	85.7	109	15	7	8	1	4	4	+46
De'Aaron Fox	3	122	2021-22	SAC	38.8	40.7	2.3	7.7	1.3	1.3	2.3	15.7	29.0	54.0	3.3	6.7	50.0	6.0	6.7	90.0	117	7	23	4	4	7	11	-21