Since 2009-10, James Harden has the most games with 50+ points in a season, with 9 games in 2018-19.

players with the most 50 point games in a single season since 2010

Interpreted as:

players with the most 50 or more point games in a single season since 2010

NAME	GP	PTS	SEASON	TM	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	REB	AST	STL	BLK	TOV	PF	+/-
James Harden	9	506	2018-19	HOU	40.7	56.2	9.3	7.2	2.4	0.6	4.9	16.3	33.2	49.2	6.7	16.9	39.5	16.9	18.3	92.1	366	84	65	22	5	44	28	+113
Damian Lillard	6	334	2019-20	POR	40.3	55.7	5.0	8.7	1.0	0.0	2.7	16.7	30.3	54.9	8.0	15.3	52.2	14.3	14.8	96.6	242	30	52	6	0	16	7	+67
James Harden	5	278	2019-20	HOU	38.8	55.6	4.6	7.6	2.4	1.2	4.6	16.8	31.6	53.2	7.6	16.2	46.9	14.4	15.2	94.7	194	23	38	12	6	23	18	+84
Luka Doncic	4	214	2022-23	DAL	40.7	53.5	10.8	8.5	2.8	0.5	3.8	18.3	28.5	64.0	4.8	9.8	48.7	12.3	16.8	73.1	163	43	34	11	2	15	13	+22
James Harden	4	218	2017-18	HOU	41.6	54.5	4.8	10.3	2.5	0.5	6.5	17.0	27.5	61.8	5.5	10.5	52.4	15.0	16.8	89.6	166	19	41	10	2	26	16	+27
Russell Westbrook	4	216	2016-17	OKC	40.0	54.0	11.3	10.0	2.3	0.3	4.5	19.0	38.8	49.0	4.0	11.5	34.8	12.0	14.5	82.8	160	45	40	9	1	18	11	+32
Devin Booker	3	166	2023-24	PHX	38.3	55.3	4.0	6.0	0.3	1.0	2.7	19.7	31.7	62.1	6.7	13.0	51.3	9.3	10.0	93.3	115	12	18	1	3	8	5	+21
Joel Embiid	3	171	2023-24	PHI	36.9	57.0	14.3	5.0	1.3	1.0	3.0	20.0	31.7	63.2	0.7	1.7	40.0	16.3	18.0	90.7	111	43	15	4	3	9	9	+23
Tyrese Maxey	3	153	2023-24	PHI	44.8	51.0	4.7	4.3	0.7	1.3	1.0	18.7	33.3	56.0	5.3	10.0	53.3	8.3	8.7	96.2	134	14	13	2	4	3	8	+29
Damian Lillard	3	181	2022-23	POR	39.6	60.3	5.0	5.7	1.3	0.0	2.3	19.7	31.7	62.1	9.0	16.7	54.0	12.0	13.0	92.3	119	15	17	4	0	7	2	+30
Giannis Antetokounmpo	3	159	2022-23	MIL	34.4	53.0	14.0	4.3	0.7	0.0	3.7	20.3	32.7	62.2	1.7	5.0	33.3	10.7	14.3	74.4	103	42	13	2	0	11	10	+51
Joel Embiid	3	164	2022-23	PHI	36.5	54.7	12.0	5.7	0.3	3.3	3.3	19.7	28.3	69.4	1.0	3.0	33.3	14.3	16.0	89.6	110	36	17	1	10	10	8	+53
Kevin Durant	3	159	2021-22	BKN	42.2	53.0	6.7	7.0	1.3	0.7	4.7	18.0	32.0	56.3	5.7	11.0	51.5	11.3	12.7	89.5	127	20	21	4	2	14	9	+37
Stephen Curry	3	172	2020-21	GSW	36.4	57.3	4.3	4.3	0.3	0.0	4.3	17.0	28.7	59.3	9.7	17.7	54.7	13.7	14.3	95.3	109	13	13	1	0	13	6	+43
Stephen Curry	3	155	2015-16	GSW	35.1	51.7	6.0	6.3	2.3	0.3	4.7	18.7	27.3	68.3	9.7	14.7	65.9	4.7	5.0	93.3	105	18	19	7	1	14	7	+47
Luka Doncic	2	123	2023-24	DAL	44.1	61.5	8.0	11.0	2.5	1.5	4.0	20.0	29.0	69.0	8.0	14.5	55.2	13.5	14.0	96.4	88	16	22	5	3	8	3	+29
Jalen Brunson	2	111	2023-24	NYK	39.3	55.5	5.0	7.5	3.0	0.0	1.5	21.0	35.0	60.0	7.0	11.0	63.6	6.5	7.5	86.7	79	10	15	6	0	3	2	+27
Giannis Antetokounmpo	2	118	2023-24	MIL	36.9	59.0	13.0	3.0	2.0	0.5	6.0	19.5	26.5	73.6	0.0	2.0	0.0	20.0	25.0	80.0	74	26	6	4	1	12	5	+35
Devin Booker	2	109	2022-23	PHX	36.6	54.5	5.0	5.5	0.5	0.0	2.0	20.5	30.0	68.3	6.0	9.5	63.2	7.5	10.5	71.4	73	10	11	1	0	4	6	+34
Stephen Curry	2	100	2022-23	GSW	37.4	50.0	5.5	6.0	1.0	0.5	2.5	18.5	28.0	66.1	7.5	12.5	60.0	5.5	6.5	84.6	75	11	12	2	1	5	3	-25
Kyrie Irving	2	110	2021-22	BKN	36.2	55.0	4.5	5.0	2.5	1.0	2.0	17.5	25.0	70.0	8.5	12.0	70.8	11.5	13.0	88.5	72	9	10	5	2	4	7	+50
LeBron James	2	106	2021-22	LAL	37.1	53.0	8.5	4.5	0.0	1.0	3.5	18.5	28.0	66.1	6.0	10.0	60.0	10.0	10.5	95.2	74	17	9	0	2	7	3	+35
Jayson Tatum	2	105	2021-22	BOS	37.1	52.5	7.5	5.0	0.0	0.0	1.5	17.0	29.0	58.6	8.5	14.5	58.6	10.0	11.5	87.0	74	15	10	0	0	3	5	+43
Jayson Tatum	2	113	2020-21	BOS	43.2	56.5	9.0	4.5	0.0	1.0	2.5	18.0	31.0	58.1	5.5	8.5	64.7	15.0	16.5	90.9	86	18	9	0	2	5	5	+11
Bradley Beal	2	110	2020-21	WAS	38.9	55.0	6.0	3.0	1.0	1.0	2.5	19.5	33.0	59.1	5.0	8.5	58.8	11.0	13.0	84.6	78	12	6	2	2	5	4	-1