Mark Schwarzer has made the most career appearances by a Middlesbrough player in the Premier League, with 332 appearances.

most premier league appearances by a player for middlesbrough

	NAME	M	MIN	START	G	G/M	A	G+A	PK
1	Mark Schwarzer M. Schwarzer	332	29,801	332	0	0.00	1	1	0
2	Stewart Downing S. Downing	211	16,638	181	18	0.09	36	54	2
3	Robbie Mustoe R. Mustoe	197	15,159	167	10	0.05	7	17	0
4	George Boateng G. Boateng	182	15,756	177	7	0.04	9	16	0
5	Gareth Southgate G. Southgate	160	14,314	160	4	0.03	6	10	0
6	Colin Cooper C. Cooper	158	12,460	139	5	0.03	2	7	0
7	Steve Vickers S. Vickers	156	13,222	149	2	0.01	1	3	0
8	Franck Queudrue F. Queudrue	150	12,545	145	11	0.07	15	26	0
9	Curtis Fleming C. Fleming	146	12,551	141	2	0.01	6	8	0
10	Ugo Ehiogu U. Ehiogu	126	10,574	122	7	0.06	1	8	0
11	Juninho Paulista J. Paulista	125	9,939	113	29	0.23	18	47	0
12	Szilárd Németh S. Németh	117	5,989	62	23	0.20	8	31	0
13	Emanuel Pogatetz E. Pogatetz	110	9,419	106	4	0.04	6	10	0
14	Hamilton Ricard H. Ricard	106	7,352	88	31	0.29	9	40	5
15	Gianluca Festa G. Festa	100	8,361	94	8	0.08	2	10	0
16	Jonathan Greening J. Greening	99	8,026	91	4	0.04	4	8	0
17	Chris Riggott C. Riggott	98	8,042	91	5	0.05	0	5	0
18	Paul Ince P. Ince	93	8,267	93	7	0.08	4	11	0
19	Phil Stamp P. Stamp	93	5,430	58	6	0.06	5	11	0
20	Andrew Taylor A. Taylor	92	7,299	79	0	0.00	1	1	0
21	Joseph Desiré Job J. Desiré Job	92	5,499	62	16	0.17	9	25	0
22	Stuart Parnaby S. Parnaby	91	6,427	73	2	0.02	2	4	0
23	Brian Deane B. Deane	87	6,696	72	18	0.21	7	25	1
24	Massimo Maccarone M. Maccarone	81	4,302	46	18	0.22	8	26	4
25	Derek Whyte D. Whyte	81	6,862	78	0	0.00	1	1	0