Damian Lillard has put up the most points by a guard in a game 5, with 55 points in Game 5 of the 2021 First Round against the Nuggets.

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Damian Lillard D. Lillard	55	6/1/2021	POR	@	DEN	52	6	10	1	3	17	24	70.8	12	17	70.6	9	10	90.0	96.8	1	5	1	0	+2
2	Allen Iverson A. Iverson	52	5/16/2001	PHI	vs	TOR	43	2	7	4	0	21	32	65.6	8	14	57.1	2	2	100.0	79.1	0	2	1	3	+30
3	Damian Lillard D. Lillard	50	4/23/2019	POR	vs	OKC	45	7	6	3	1	17	33	51.5	10	18	55.6	6	8	75.0	68.5	2	5	6	2	+9
4	Devin Booker D. Booker	47	4/25/2023	PHX	vs	LAC	42	8	10	2	0	19	27	70.4	4	7	57.1	5	6	83.3	79.3	2	6	3	4	+11
5	Russell Westbrook R. Westbrook	47	4/25/2017	OKC	@	HOU	42	11	9	0	0	15	34	44.1	5	18	27.8	12	17	70.6	56.7	5	6	7	5	+12
6	Tyrese Maxey T. Maxey	46	4/30/2024	PHI	@	NYK	52	5	9	0	0	17	30	56.7	7	12	58.3	5	8	62.5	68.6	0	5	3	5	+3
7	Paul Pierce P. Pierce	46	5/3/2002	BOS	vs	PHI	44	4	6	1	1	16	25	64.0	8	10	80.0	6	7	85.7	81.9	1	3	0	1	+27
8	Michael Jordan M. Jordan	46	6/12/1992	CHI	@	POR	42	5	4	0	1	14	23	60.9	2	4	50.0	16	19	84.2	73.3	0	5	4	5
9	Russell Westbrook R. Westbrook	45	4/25/2018	OKC	vs	UTA	44	15	7	0	0	17	39	43.6	5	9	55.6	6	6	100.0	54.0	3	12	5	3	+10
10	Jalen Brunson J. Brunson	44	5/14/2024	NYK	vs	IND	43	4	7	0	0	18	35	51.4	2	6	33.3	6	7	85.7	57.8	0	4	3	2	+31
11	Gilbert Arenas G. Arenas	44	5/3/2006	WAS	@	CLE	53	5	4	1	0	14	24	58.3	6	9	66.7	10	10	100.0	77.5	1	4	3	4	+1
12	Michael Jordan M. Jordan	44	5/7/1989	CHI	@	CLE	44	9	6	1	0	17	32	53.1	1	1	100.0	9	13	69.2	58.3	3	6	2	3
13	Gail Goodrich G. Goodrich	44	4/25/1973	LAL	vs	GSW	36	3	8			19	26	73.1				6	7	85.7	75.7				3
14	Jamal Murray J. Murray	43	4/29/2025	DEN	vs	LAC	40	5	7	3	1	17	26	65.4	8	14	57.1	1	1	100.0	81.3	0	5	1	2	+17
15	Kobe Bryant K. Bryant	43	5/8/2012	LAL	vs	DEN	43	6	5	2	0	14	32	43.8	5	11	45.5	10	11	90.9	58.4	1	5	3	2	-6
16	Dwyane Wade D. Wade	43	6/18/2006	MIA	vs	DAL	50	4	4	3	0	11	28	39.3	0	2	0.0	21	25	84.0	55.1	0	4	3	1	+1
17	Magic Johnson M. Johnson	43	5/15/1990	LAL	vs	PHX	44	8	7	0	0	15	26	57.7	0	2	0.0	13	16	81.3	65.1	2	6	6	4
18	Jerry West J. West	43	4/11/1965	LAL	vs	BAL		6	7			17	34	50.0				9	12	75.0	54.7				3
19	Luka Dončić L. Dončić	42	6/2/2021	DAL	@	LAC	43	8	14	1	0	17	37	45.9	6	12	50.0	2	3	66.7	54.8	1	7	4	2	+15
20	Jamal Murray J. Murray	42	8/25/2020	DEN	vs	UTA	41	8	8	1	0	17	26	65.4	4	8	50.0	4	4	100.0	75.6	3	5	0	3	+20
21	Kobe Bryant K. Bryant	42	5/21/2012	LAL	@	OKC	41	5	0	2	0	18	33	54.5	1	6	16.7	5	7	71.4	58.2	0	5	2	3	-14
22	Chris Paul C. Paul	41	5/8/2018	HOU	vs	UTA	38	7	10	1	0	13	22	59.1	8	10	80.0	7	8	87.5	80.3	0	7	0	1	+20
23	Kyrie Irving K. Irving	41	6/13/2016	CLE	@	GSW	40	3	6	2	1	17	24	70.8	5	7	71.4	2	2	100.0	82.4	0	3	4	4	+20
24	Reggie Miller R. Miller	41	5/4/2000	IND	vs	MIL	39	5	1	1	0	15	25	60.0	3	7	42.9	8	10	80.0	69.7	0	5	2	4	+8
25	Michael Jordan M. Jordan	41	6/18/1993	CHI	vs	PHX	44	7	7	0	2	16	29	55.2	2	7	28.6	7	10	70.0	61.4	1	6	2	5