Between the 1999-00 and 2008-09 seasons, Thierry Henry had the most goals in Europe's top five leagues in a decade, with 205 goals in the Premier League and LaLiga in the 2000s.

	NAME	G	DECADE	M	MIN	START	G/M	A	G+A	PK
1	Thierry Henry T. Henry	205	2000s	313	25,678	286	0.65	74	279	23
2	Samuel Eto'o S. Eto'o	162	2000s	279	23,173	264	0.58			18
3	Rudolphus Antonius Makaay R. Antonius Makaay	157	2000s	262	20,781	239	0.60			12
4	Pauleta	149	2000s	296	23,062	258	0.50	0	149	24
5	Francesco Totti F. Totti	142	2000s	272	23,265	268	0.52			40
6	Ruud van Nistelrooij R. van Nistelrooij	140	2000s	217	17,748	201	0.65	14	154	25
7	Raúl	139	2000s	338	27,952	319	0.41			5
8	David Trezeguet D. Trezeguet	138	2000s	225	16,863	195	0.61			6
9	Andriy Shevchenko A. Shevchenko	136	2000s	273	19,727	225	0.50	7	143	25
10	Luca Toni L. Toni	129	2000s	233	19,697	227	0.55	6	135	6
11	Michael Owen M. Owen	120	2000s	255	18,240	206	0.47	16	136	11
12	Claudio Pizarro C. Pizarro	119	2000s	277	19,156	204	0.43	3	122	3
13	Raúl Tamudo R. Tamudo	119	2000s	301	23,796	277	0.40			30
14	Hernán Crespo H. Crespo	118	2000s	245	16,699	194	0.48	1	119	9
15	Alessandro Del Piero A. Del Piero	118	2000s	268	19,526	228	0.44			35
16	David Villa D. Villa	117	2000s	207	17,093	199	0.57			28
17	Djibril Cissé D. Cissé	117	2000s	269	19,427	215	0.43	5	122	7
18	Jimmy Floyd Hasselbaink J. Floyd Hasselbaink	117	2000s	253	18,868	212	0.46	39	156	17
19	Christian Vieri C. Vieri	117	2000s	200	13,434	140	0.59			15
20	Miroslav Klose M. Klose	117	2000s	262	20,682	239	0.45	7	124	6
21	Robbie Keane R. Keane	115	2000s	313	22,411	250	0.37	35	150	16
22	Fernando Torres F. Torres	113	2000s	231	19,319	222	0.49	7	120	18
23	Alberto Gilardino A. Gilardino	113	2000s	281	18,973	207	0.40			9
24	Diego Forlán D. Forlán	112	2000s	238	17,026	188	0.47	6	118	11
25	Alan Shearer A. Shearer	107	2000s	225	19,550	220	0.48	25	132	28